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	<title type="text">Jessica Craig | Vox</title>
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	<updated>2025-12-01T14:58:09+00:00</updated>

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			<title type="html"><![CDATA[Want to help save the most lives possible? Here’s where to give money.]]></title>
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							<summary type="html"><![CDATA[If you want to help human beings alive right now, there are few better places to give than global health. Diseases that have been largely eradicated in the US still claim hundreds of thousands of lives abroad. In 2022, the most recent year for which there’s data, ten Americans died of malaria; all acquired it [&#8230;]]]></summary>
			
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<img alt="People reinforcing the shape of a caduceus from within its wings. They are surrounded by various bacteria and health threats." data-caption="Saving lives with donations is possible. | Lorena Spurio for Vox" data-portal-copyright="Lorena Spurio for Vox" data-has-syndication-rights="1" src="https://platform.vox.com/wp-content/uploads/sites/2/2024/12/LorenaSpurio_Colours_1.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
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	Saving lives with donations is possible. | Lorena Spurio for Vox	</figcaption>
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<p class="has-text-align-none">If you want to help human beings alive right now, there are few better places to give than global health.</p>

<p class="has-text-align-none">Diseases that have been largely eradicated in the US still claim hundreds of thousands of lives abroad. In 2022, the most recent year for which there’s data, <a href="https://www.cdc.gov/malaria/php/surveillance-report/2022.html" data-type="link" data-id="https://www.cdc.gov/malaria/php/surveillance-report/2022.html">ten Americans died of malaria</a>; all acquired it abroad. But the World Health Organization estimates that worldwide, <a href="https://iris.who.int/bitstream/handle/10665/330011/9789241565721-eng.pdf?page=52" data-type="link" data-id="https://iris.who.int/bitstream/handle/10665/330011/9789241565721-eng.pdf?page=52">600,000 people died</a> of it that year, most of them children in Africa.</p>

<div class="wp-block-vox-media-highlight vox-media-highlight">
<h2 class="wp-block-heading" id="if-you-don-t-want-to-think-about-individual-charities-at-all-the-simplest-move-is-to-give-to-givewell-top-charities-fund">If you don’t want to think about individual charities at all, the simplest move is to give to <strong>GiveWell Top Charities Fund</strong>.&nbsp;</h2>



<p class="has-text-align-none">You can stop reading here and feel very good about it. </p>



<p class="has-text-align-none">If you want to see how the sausage is made — and what other high-impact options exist — keep going. Check out the following causes: </p>



<ul class="wp-block-list">
<li><a href="#fighting-malaria">Fighting malaria</a></li>



<li><a href="#giving-kids-vitamin-a">Giving kids vitamin A</a></li>



<li><a href="#backing-vaccinations">Backing vaccinations</a></li>



<li><a href="#supporting-local-ngos">Supporting local NGOs</a></li>



<li><a href="#aid-to-sudan">Aid to Sudan</a></li>



<li><a href="#surveillance-to-find-the-next-pandemic">Surveillance to find the next pandemic</a></li>



<li><a href="#ending-lead-poisoning">Ending lead poisoning</a></li>



<li><a href="#combatting-superbugs">Combatting superbugs</a></li>
</ul>
</div>

<p class="has-text-align-none">For a long time, the world was slowly pushing those numbers down. That progress is now at real risk.</p>

<p class="has-text-align-none">In 2025, the Trump administration effectively dismantled USAID, canceling or gutting thousands of health programs and shifting a skeleton of its staff into the State Department. Other governments around the world have pulled back their funding, too. A <a href="https://www.impactcounter.com/dashboard?view=table&amp;sort=interval_minutes&amp;order=asc">conservative real-time tracker</a> attributes roughly 600,000 deaths so far to the collapse of USAID, with <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01186-9/fulltext">modelling suggesting</a> that if cuts on this scale continues, they could lead to more than 14 million additional deaths by 2030 from diseases like malaria, tuberculosis, diarrhea, and respiratory infections.</p>

<p class="has-text-align-none">The weird, hopeful part is that global health interventions are fairly cheap. that&#8217;s how the US and other rich countries succeeded in stamping out these diseases. That is an opportunity for people seeking to give and make others’ lives better: It means that saving a life in a relatively poor country is possible at relatively low cost.</p>

<p class="has-text-align-none"><a href="https://givewell.org/">GiveWell</a>, our favorite evaluator of global health charities, estimates that the groups it recommends can <a href="https://www.givewell.org/how-much-does-it-cost-to-save-a-life">save a life for $3,500 to $5,500</a>. Put another way, giving $300 a month for a year could be enough to save someone’s life. There are gym memberships that cost more than that. And there’s never been a better time to make a difference as an individual donor to the health and well-being of people around the world.</p>

<p class="has-text-align-none">So if you want to donate to improve<strong> </strong>global health, where should you start? There are too many good causes to list here, but hopefully, the ones below give you some ideas.</p>

<h2 class="wp-block-heading" id="fighting-malaria">Fighting malaria</h2>

<p class="has-text-align-none">GiveWell, the charity evaluator, currently lists four groups on its <a href="https://www.givewell.org/charities/top-charities">“top charities” list</a>. Two of them focus on malaria: <a href="https://www.givewell.org/charities/amf">Against Malaria Foundation</a> and the <a href="https://www.givewell.org/charities/malaria-consortium">Malaria Consortium</a>.</p>

<p class="has-text-align-none">The two groups take two different approaches to preventing malaria transmission, both of which are extremely cost-effective. Against Malaria focuses on funding and distributing insecticide-treated nets, which people in malarial regions (largely sub-Saharan Africa but also parts of South Asia) can sleep under and protect themselves from bites by malaria-carrying mosquitos.</p>

<div class="wp-block-vox-media-highlight vox-media-highlight">
<h2 class="wp-block-heading">The Vox guide to giving</h2>



<p class="has-text-align-none">The holiday season is giving season. This year, Vox is exploring every element of charitable giving —&nbsp;from making the case for donating 10 percent of your income, to recommending specific charities for specific causes, to explaining what you can do to make a difference beyond donations. <a href="https://www.vox.com/charitable-giving">You can find all of our giving guide stories here</a>.</p>
</div>

<p class="has-text-align-none"></p>

<p class="has-text-align-none">The nets themselves are incredibly cheap. GiveWell estimates that <a href="https://www.givewell.org/impact-estimates" data-type="link" data-id="https://www.givewell.org/impact-estimates">Against Malaria</a> can provide a net for 6 each. You may have heard in the news that bednets are sometimes used for other purposes, like <a href="https://www.vox.com/future-perfect/2024/1/25/24047975/malaria-mosquito-bednets-prevention-fishing-marc-andreessen">fishing</a>. That’s true. GiveWell estimates, based on past studies and their own research, that about <a href="https://www.givewell.org/research/grants/AMF-LLIN-DRC-June-2024" data-type="link" data-id="https://www.givewell.org/research/grants/AMF-LLIN-DRC-June-2024">75 percent</a> of nets distributed will be used as intended. And<strong> </strong>the intervention is still incredibly cost-effective. A meta-analysis looking at five randomized studies of bednets found that <a href="https://www.givewell.org/international/technical/programs/insecticide-treated-nets#How_do_net_distributions_affect_malaria_cases">mortality from any cause fell by 17 percent</a> among children targeted for bednet distribution (whether they used the nets or not); they were 45 percent less likely to get malaria. The effect on children actually using the nets is, of course, much greater.</p>

<p class="has-text-align-none">The other program GiveWell recommends donating to is the <a href="https://www.givewell.org/charities/malaria-consortium">Malaria Consortium’s Seasonal Malaria Chemoprevention initiative</a>, which uses another approach to prevent malaria infections. “Chemoprevention” means giving antimalarial medications to at-risk people before they’re bitten by a mosquito, in hopes of preventing a malaria infection. The campaigns are seasonal because in many malarial regions, malaria-carrying mosquitos only thrive and transmit the disease in certain seasons, often during a summer rainy season where there’s more water for mosquitos to breed in.</p>

<p class="has-text-align-none">Seasonal chemoprevention is a newer approach than bednets, but there’s <a href="https://www.givewell.org/international/technical/programs/seasonal-malaria-chemoprevention#Reduced_mortality_for_young_children">very strong evidence</a> that it’s effective at stopping malaria transmission. GiveWell cites a <a href="https://www.mmv.org/sites/default/files/uploads/docs/access/SMC_Tool_Kit/publications/Meremikww-ipt-review.pdf">Cochrane Collaboration review</a> of six randomized studies that found that malaria cases among young children fall by 73 percent due to seasonal chemoprevention campaigns. GiveWell itself <a href="https://www.givewell.org/international/technical/programs/seasonal-malaria-chemoprevention#Reduced_mortality_for_young_children" data-type="link" data-id="https://www.givewell.org/international/technical/programs/seasonal-malaria-chemoprevention#Reduced_mortality_for_young_children">extended that review</a> to add two newer studies, and drop an older one that they thought less relevant, and got a similar number: 79<strong> </strong>percent less malaria among young children.&nbsp;</p>

<p class="has-text-align-none">A year of chemoprevention costs very little per person, about <a href="https://www.givewell.org/international/technical/programs/seasonal-malaria-chemoprevention#Summary-01">$7 on average</a>. Combining that low cost with that degree of effectiveness makes it a very inexpensive way to save someone’s life.</p>

<h2 class="wp-block-heading" id="giving-kids-vitamin-a">Giving kids vitamin A</h2>

<p class="has-text-align-none">It’s pretty easy to get enough vitamin A if you’re in a rich country and can easily access leafy greens like spinach or lettuce, or other vegetables like carrots. But in many poor countries, <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10416138/">vitamin A deficiency is a serious problem</a>, which in children can lead to stunting, blindness, or even death.&nbsp;</p>

<p class="has-text-align-none">Thankfully, there’s a simple way to fight vitamin A deficiency: Give people vitamin A. <a href="https://www.givewell.org/charities/helen-keller-international">Helen Keller International</a>, a charity founded in 1915 by Keller, the noted deaf-blind writer and activist, is one of the world’s leading groups supporting vitamin A supplementation campaigns, and one of GiveWell’s top recommended charities. It subsidizes governments in affected countries and provides technical support for mass campaigns to distribute vitamin A capsules (about $1 each to deliver) to households with children.</p>

<p class="has-text-align-none">GiveWell recommends Helen Keller because vitamin A supplementation, in their view, significantly reduces child mortality, by about 4 to 12 percent. They <a href="https://www.givewell.org/international/technical/programs/vitamin-A#Reduced_mortality_for_young_children">base this</a>, as with their malaria judgments, on a <a href="https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD008524.pub3/epdf/full">Cochrane meta-analysis</a>, which, depending on assumptions used, concluded that vitamin A supplementation reduces mortality by between 12 and 24 percent. That said, the largest study included there <a href="https://files.givewell.org/files/DWDA%202009/Interventions/Vitamin%20A/Awasthi_etal_2013a_VitaminASupplementation.pdf">produced a much smaller estimate</a> (4 percent). GiveWell leans conservative, <a href="https://www.givewell.org/international/technical/programs/vitamin-A">assuming that</a>, over time, with better global nutrition, the impact is likely on the lower end of that spectrum.</p>

<p class="has-text-align-none">But even a 4 percent drop in mortality for $1 is a stunningly good deal. What&#8217;s more, vitamin A supplementation has other benefits. </p>

<p class="has-text-align-none">It can prevent blindness and stunting, helping children grow up with healthy vision and to healthy heights and weights, which could <a href="https://www.givewell.org/international/technical/programs/vitamin-A#Long-term_income_increases">translate into higher incomes</a> and other benefits as an adult. Though the evidence here is less voluminous than on mortality, it&#8217;s important to remember that there&#8217;s more to global health than just preventing deaths. Vitamin A can prevent deaths, but it also makes the lives it saves easier and more fulfilling.</p>

<h2 class="wp-block-heading" id="backing-vaccinations">Backing vaccinations</h2>

<p class="has-text-align-none">A landmark 2024<strong> </strong>study from the WHO suggested that in the past fifty years, <a href="https://www.vox.com/future-perfect/24138291/do-vaccines-work-explained-study-efficacy-evidence">vaccines have saved 154 million lives</a>, the vast majority of children under 5. Yet vaccine-preventable illnesses like <a href="https://www.vox.com/future-perfect/369095/hepatitis-vaccine-deaths-symptoms-infections">hepatitis A and B</a> or <a href="https://www.thelancet.com/action/showPdf?pii=S1473-3099(24)00176-2&amp;page=18">streptococcus pneumoniae</a> still kill millions every year. Expanding access to the vaccines we already have can be as important as developing new ones.</p>

<p class="has-text-align-none">But reaching the so-called last mile of hard-to-reach populations not currently being vaccinated can be difficult. <a href="https://www.givewell.org/international/technical/programs/new-incentives" data-type="link" data-id="https://www.givewell.org/international/technical/programs/new-incentives">New Incentives</a>, the fourth and final charity recommended by GiveWell, tries a simple method to reach them: offering money. It gives cash incentives of around $5-8 to parents and other adults in northern Nigeria as an incentive to get <a href="https://www.givewell.org/charities/new-incentives#Vaccines_incentivized">vaccinated against</a> against measles, pneumococcal disease, tuberculosis, and the five diseases the pentavalent vaccine protects against (diphtheria, tetanus, pertussis, hepatitis B, and Hib).</p>

<p class="has-text-align-none">A <a href="https://files.givewell.org/files/DWDA%202009/NewIncentives/IDinsight_Impact_Evaluation_of_New_Incentives_Final_Report.pdf">randomized trial</a> of New Incentives&#8217;s programs released in 2020 found that overall, children targeted by the program were <a href="https://www.givewell.org/international/technical/programs/new-incentives#How_much_does_the_program_increase_vaccination_rates">22 percentage points more likely to be vaccinated</a>: 36 percent of children in the control group were immunized, compared to 58 percent in the group receiving incentives. And the program has rapidly scaled. By 2023, New Incentives had <a href="https://www.givewell.org/research/lookbacks/New-Incentives-2025#How_did_implementation">enrolled over</a> 1.5 million infants.</p>

<p class="has-text-align-none">Even if you suspect the actual impact isn’t quite that significant, the program is extremely cost-effective; roughly 9 to 18 percentage points according to GiveWell’s estimates. And that cost-effectiveness has actually improved. Due to the devaluation of the Nigerian currency Naira in 2024 and 2025, a US dollar now funds significantly more incentives than before.</p>

<h2 class="wp-block-heading" id="supporting-local-ngos">Supporting local NGOs</h2>

<p class="has-text-align-none">Empowering and funding local, community-based organizations — as opposed to large, global agencies such as the World Health Organization or the Red Cross — helps create a more nimble, sustainable, and culturally relevant aid environment. Local organizations not only have a better understanding of local needs, but they can respond faster to emergencies.&nbsp;</p>

<p class="has-text-align-none">But in late 2025, this has become more complicated. For years, agencies like USAID pledged to shift 25 percent of their funding to local partners. With the dissolution of USAID and the retreat of major Western donors this year, those pledges have evaporated. The agencies are gone, leaving local groups as the primary — and often only — safety net for their communities.</p>

<p class="has-text-align-none">Here are some local NGOs working to address challenges from health care and gender-based violence to unemployment and social development:&nbsp;</p>

<ul class="wp-block-list">
<li><a href="https://taimaka.org/">Taimaka</a> is a Nigerian nonprofit in the Gombe State that treats children with severe malnutrition through community health workers, shifting care from crowded hospitals. They use a simple app to diagnose and track kids in their villages, treating a child for roughly $94 — less than half what standard programs cost — and early estimates suggest that it saves lives at around the same cost as the best-known malaria charities. My colleague Sigal Samuel wrote more about their work <a href="https://www.vox.com/future-perfect/468551/child-hunger-malnutrition-taimaka-future-perfect-25">here</a>.</li>



<li>For 19<strong> </strong>years, <a href="https://www.rwamrec.org/">Rwanda Men’s Resource Centre</a> has worked to teach healthy masculinity, promote gender equality, and reduce gender-based violence. For the past five years, gender-based violence has been steadily <a href="https://www.ecoi.net/en/document/2101192.html">rising</a> in the east African country. According to 2020 survey data, almost 40 percent of girls and women aged 15–49 years have experienced physical, sexual, or psychological violence. The NGO has a variety of training programs and community engagement events that teach couples and young people how to resolve conflict and cohabitate peacefully, improve communication and joint decision-making, and to leverage new tools to improve financial instability. </li>



<li><a href="https://afyaresearch.org/about-us/">Afya Research Africa</a> is a Kenyan NGO working toward universal health coverage by providing affordable primary care in rural communities. The organization funds door-to-door health services and supports brick-and-mortar health clinics and pharmacies. Afya also provides rare funding for its clinicians to conduct locally relevant research.</li>
</ul>

<h2 class="wp-block-heading" id="aid-to-sudan">Aid to Sudan</h2>

<p class="has-text-align-none">Sudan <a href="https://www.vox.com/future-perfect/467671/sudan-civil-war-space-rsf-famine-explained" data-type="link" data-id="https://www.vox.com/future-perfect/467671/sudan-civil-war-space-rsf-famine-explained">continues to face</a> the most devastating humanitarian crisis in the world. For more than a year, the country has been embroiled in a <a href="https://www.vox.com/world-politics/23712710/sudan-war-khartoum-burhan-hemedt-rsf">civil war</a> that has displaced nearly 12 million<s>s</s> people, pushed entire communities<strong> </strong>into famine, and crippled the national banking, health care, and telecommunications systems. </p>

<p class="has-text-align-none">And yet, the conflict remains one of the most neglected in the world. As of November, the United Nations has received <a href="https://fts.unocha.org/plans/1220/summary">only about a third</a> of the humanitarian funding it requested earlier this year — leaving a gap of nearly $2.8 billion.</p>

<p class="has-text-align-none">Meanwhile, staff from international aid and human rights groups have repeatedly faced challenges <a href="https://www.rescue.org/article/crisis-sudan-what-happening-and-how-help">accessing</a> the most fragile parts of the country while other organizations have been forced to <a href="https://www.thenewhumanitarian.org/news/2023/08/01/exclusive-sudanese-aid-workers-face-hundreds-job-losses">lay off</a> local aid workers due to insecurity and budgetary constraints. These local and international NGOs are still working to fill critical gaps across Sudan and in neighboring countries hosting refugees from Sudan:</p>

<ul class="wp-block-list">
<li>Doctors Without Borders (MSF) provides health services to thousands of people across Sudan despite recurrent attacks against health care workers and health clinics. MSF doctors and nurses have treated tens of thousands of people facing malnutrition to avert famine-related deaths. The NGO is also working to quell a <a href="https://www.msf.org/war-fuels-cholera-outbreak-across-sudan" data-type="link" data-id="https://www.msf.org/war-fuels-cholera-outbreak-across-sudan">cholera outbreak</a> and to ramp up care for malnutritioned children and expecting <a href="https://www.msf.org/sudan-pregnant-women-and-children-dying-shocking-numbers-south-darfur">mothers</a> who are dying from preventable infectious diseases. In many places, MSF clinics are the only functioning health care facilities still caring for people. </li>



<li>The <a href="https://sapa-usa.org/">Sudanese American Physicians Association</a> (SAPA) is a lifeline for the country’s collapsing health system. This diaspora-led group uses its network to fund and supply hospitals that have been abandoned by the state. They provide salaries for local doctors who haven&#8217;t been paid in years and source critical supplies for surgeries and maternity care.</li>



<li><a href="https://www.wearealight.org/sudan">Alight</a> is a local group providing health care across five Sudanese states. Currently, the organization runs 42 primary health clinics, a field hospital, and four mobile health facilities. The NGO recently launched a program to feed mothers who give birth in severely resource-limited refugee camps.&nbsp;</li>
</ul>

<h2 class="wp-block-heading" id="surveillance-to-find-the-next-pandemic">Surveillance to find the next pandemic</h2>

<p class="has-text-align-none">Most years, the <a href="https://www.npr.org/sections/goats-and-soda/2024/11/07/g-s1-30783/tb-tuberculosis-deadliest-infectious-disease-covid">deadliest infectious disease in the world is tuberculosis</a>, a brutal bacterium that’s also frustratingly expensive to eradicate (which is why none of GiveWell’s top charities <a href="https://www.givewell.org/international/technical/programs/mass-screen-and-treatment-programs-tuberculosis">target it</a>). But in 2020, 2021, and 2022, there was a new deadliest-disease, and you can probably guess its name: Covid-19.</p>

<p class="has-text-align-none">All told, the Sars-Cov-2 virus has <a href="https://data.who.int/dashboards/covid19/deaths?n=o">killed over 7 million people</a>, with estimates of “excess deaths” (including deaths due to disruptions to the economy and health care access, and ones due to Covid but not reported as such) <a href="https://www.economist.com/graphic-detail/coronavirus-excess-deaths-estimates">reaching into 20 to 30 million</a>. The world spent untold trillions to fight the pandemic. It would have been much more humane, and cheaper, to have prevented it in the first place.</p>

<p class="has-text-align-none">Ultimately, pandemic monitoring and prevention is the job of governments rather than charities, but there are nonetheless some valuable groups working to prevent a repeat of the Covid experience. One is the <a href="https://naobservatory.org/">Nucleic Acid Observatory</a>, a project developing ways to surveil wastewater and other sources and notice when novel pathogens start showing up. The technologies they&#8217;re helping to build could help us catch things like Covid weeks or months earlier, and give us time to squash them before they become full-fledged pandemics.</p>

<h2 class="wp-block-heading" id="ending-lead-poisoning">Ending lead poisoning</h2>

<p class="has-text-align-none"><a href="https://www.vox.com/future-perfect/22834666/lead-exposure-poisoning-developing-countries">Lead poisoning</a> has, historically, been a major blind spot in the global health world. The extent of the problem is enormous: A <a href="https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(20)30278-3/fulltext">landmark study</a> found that about half of children in poor countries are exposed to very high levels of lead. At least <a href="https://www.who.int/news-room/fact-sheets/detail/lead-poisoning-and-health">1.5 million people die</a> annually from cardiovascular diseases (like heart disease) caused by lead poisoning, imposing a global economic cost of about <a href="https://www.thelancet.com/journals/lanplh/article/PIIS2542-5196(23)00166-3/fulltext">$6 trillion a year</a>.</p>

<p class="has-text-align-none">But the resources devoted to preventing lead poisoning were minimal. One <a href="https://rethinkpriorities.org/publications/global-lead-exposure-report">estimate in 2021</a> found that charities and nongovernmental organizations were spending between&nbsp; $6 and 10 million a year on the problem. That’s less than two cents per child poisoned by lead.</p>

<p class="has-text-align-none">While there are several worthwhile charities working on this issue, I (Dylan) recommend in particular <a href="https://www.pureearth.org/">Pure Earth</a>, which has been a leader on lead and metal contamination for decades; the <a href="https://leadelimination.org/">Lead Exposure Elimination Project</a>, which has been influential in fighting lead paint specifically in developing countries; and the <a href="https://www.cgdev.org/publication/call-action-end-childhood-lead-poisoning-worldwide-neglected-top-tier-development">Center for Global Development</a>, which has become the center of lead policy in the global health world and helped make the issue a bigger priority in recent years.</p>

<h2 class="wp-block-heading" id="combatting-superbugs">Combatting superbugs</h2>

<p class="has-text-align-none">Researchers estimated that more than <a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(21)02724-0/fulltext?mkt_tok=NDkwLUVIWi05OTkAAAGCOwuIZk6PC62ka11T3aZOVQ4bGfdDtfrsMK0TZRNysKlXpBt2Ki44YMDQkmCs6r9ZTVnfOJb4dOfOJHV7uPHuCC4uZKs87QwUCxNFKMtQhwFe">1 million</a> people died globally from antibiotic-resistant infections in 2019. Despite the emerging crisis, antibiotic research and development has long stalled. No large US or European pharmaceutical company is working to develop new antibiotics.&nbsp;</p>

<p class="has-text-align-none">Fortunately, a small but growing group of researchers and clinicians has been working to revive a decades-old treatment for drug-resistant infections: <a href="https://www.vox.com/the-highlight/373174/phage-therapy-antiobiotic-resistance-africa-innovation">bacteriophages</a>, viruses that target and kill bacteria. Phage therapy is starting to make inroads in the US and Europe, though clinicians still have to request emergency use authorization from the Food and Drug Administration, or equivalent agencies, before the treatment can be used. Today, there are some <a href="https://clinicaltrials.gov/search?intr=Bacteriophage">80 clinical trials</a> for phage therapy in the US alone.&nbsp;</p>

<p class="has-text-align-none">But while phage therapy is gaining ground in developed countries, many developing countries in Africa and Asia are falling behind, even though the burden of drug-resistant infections is highest in these countries. A lack of regulatory agencies to review and approve the treatment is one major barrier. Another is an absence of local manufacturing infrastructure, which has hindered local drug development in developing countries for years.&nbsp;</p>

<p class="has-text-align-none">Researchers consistently demonstrate that phage therapy is safe and effective for treating drug-resistant infections, even those caused by bacteria that no known antibiotics can treat. What is needed now is for the phage therapy technology and expertise to be transferred to developing countries.&nbsp;</p>

<p class="has-text-align-none">That is the mission of <a href="https://www.phagesforglobalhealth.org/">Phages for Global Health</a>, an NGO run by Tobi Nagel and an international team of physician researchers. The organization trains laboratory technologists in Africa and Asia to study phages in their labs and partners with institutes to conduct research and develop new phage products that can be used, for instance, to prevent and quell cholera outbreaks and decontaminate poultry products to prevent foodborne illness.</p>
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									</content>
			
					</entry>
			<entry>
			
			<author>
				<name>Jessica Craig</name>
			</author>
			
			<title type="html"><![CDATA[The devastating impact of Trump’s slashing foreign aid, in 3 charts]]></title>
			<link rel="alternate" type="text/html" href="https://www.vox.com/future-perfect/404040/foreign-aid-cuts-trump-charts-usaid-pepfar-who-hiv" />
			<id>https://www.vox.com/?p=404040</id>
			<updated>2025-03-17T12:45:25-04:00</updated>
			<published>2025-03-16T06:00:00-04:00</published>
			<category scheme="https://www.vox.com" term="Donald Trump" /><category scheme="https://www.vox.com" term="Future Perfect" /><category scheme="https://www.vox.com" term="Health" /><category scheme="https://www.vox.com" term="Policy" /><category scheme="https://www.vox.com" term="Politics" /><category scheme="https://www.vox.com" term="Public Health" />
							<summary type="html"><![CDATA[In about three short months, the Trump administration took a wrecking ball to foreign aid, threatening millions of lives and livelihoods around the world. After initially pausing all US foreign aid spending for 90 days, President Donald Trump handed over the reins to Elon Musk’s Department of Government Efficiency (DOGE). The damage as DOGE went [&#8230;]]]></summary>
			
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<img alt="" data-caption="A child gets a malaria vaccination at a hospital in Yala, Kenya, on October 7, 2021." data-portal-copyright="" data-has-syndication-rights="1" src="https://platform.vox.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/24714863/1235749028.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
	<figcaption>
	A child gets a malaria vaccination at a hospital in Yala, Kenya, on October 7, 2021.	</figcaption>
</figure>
<p class="has-text-align-none">In about three short months, the Trump administration took a wrecking ball to foreign aid, <a href="https://www.vox.com/future-perfect/402944/pepfar-hiv-donald-trump-elon-musk-global-health">threatening millions of lives</a> and livelihoods around the world. After <a href="https://www.whitehouse.gov/presidential-actions/2025/01/reevaluating-and-realigning-united-states-foreign-aid/">initially pausing all US foreign aid spending</a> for 90 days, President Donald Trump handed over the reins to Elon Musk’s <a href="https://doge.gov/">Department of Government Efficiency</a> (DOGE).</p>

<p class="has-text-align-none">The damage as DOGE went about clear-cutting the US Agency for International Development (USAID) was swift and extensive. Health clinics from <a href="https://tolonews.com/health-193039">Afghanistan</a> to <a href="https://time.com/7258248/us-foreign-aid-burundi-patients-essay/">Burundi</a> shuttered. Oxygen tanks, HIV and malaria medications, and other medical supplies amounting to at least <a href="https://www.reuters.com/world/us/usaid-disruptions-leave-oxygen-tanks-tb-drugs-stuck-ships-warehouses-2025-02-13/">$240 million</a> remain <a href="https://www.nbcnews.com/news/politics-news/trump-usaid-upheaval-paralyzing-global-delivery-food-medicine-rcna190565">stuck at ports or storage facilities</a> around the world. Ebola prevention and response funding, which <a href="https://www.youtube.com/watch?v=P4To-CU5SIM">Musk claimed</a> at the end of February was restored with “no interruption” during the 90-day freeze, is <a href="https://www.npr.org/sections/goats-and-soda/2025/02/27/g-s1-50929/elon-musk-ebola-usaid">reportedly still not operational</a>, according to several public health experts. Whether it’s aid for malnutrition, clean water, or outbreak response, even a handful of days can undo years of progress in the making.</p>

<p class="has-text-align-none">The Trump administration slashed at least <a href="https://apnews.com/article/trump-usaid-foreign-aid-cuts-6292f48f8d4025bed0bf5c3e9d623c16">$54 billion in foreign aid contracts</a>. Around the world, <a href="https://www.usaidstopwork.com/">around 60,000 aid workers lost their jobs</a>, including some <a href="https://www.bbc.com/news/articles/cr42r2gw5wzo">2,000</a> <a href="https://www.usaid.gov/">USAID employees</a>. Much of the world has lost its primary health support, and they won’t get it back anytime soon. Secretary of State Marco Rubio, who <a href="https://www.cnn.com/2025/02/03/politics/usaid-washington-workers/index.html">took over as USAID’s interim leader</a> in early February, announced Monday that <a href="https://apnews.com/article/trump-musk-rubio-usaid-foreign-aid-bf442d62af67918a6fc5eee839074601">83 percent of the agency’s programs</a> had been canceled, while other restored projects have been shrunk considerably.</p>

<p class="has-text-align-none">The administration has not yet published a full list of all affected programs and projects. But former USAID workers and contractors are counting up canceled projects based on termination notices received by project staff. So far, <a href="https://apnews.com/article/usaid-cuts-hunger-sickness-288b1d3f80d85ad749a6d758a778a5b2">many foundational global health efforts</a> to treat malnutrition, prevent newborn and maternal mortality, or eliminate infectious diseases such as HIV, malaria, tuberculosis, malnutrition, and polio have been impacted. Projects that aimed to improve infectious disease surveillance in foreign countries and to help prevent and contain future pandemics — which could directly impact American health and security — were also cut. </p>

<p class="has-text-align-none">These cuts and the US’s recent <a href="https://www.vox.com/future-perfect/399581/trump-who-world-health-organization-public-health">withdrawal from the World Health Organization</a> come on top of <a href="https://www.thinkglobalhealth.org/article/defining-moment-global-health-funding">years of declines in global funding for health</a>. The timing couldn’t be possibly worse: Five years after the Covid pandemic began, the world now faces a surge of infectious disease outbreaks from <a href="https://www.weforum.org/stories/2024/11/dengue-fever-outbreak-climate-change/">dengue</a> and <a href="https://www.who.int/news-room/fact-sheets/detail/malaria#:~:text=According%20to%20the%20latest%20World,to%20600%20000%20in%202022.">malaria</a> to <a href="https://www.cidrap.umn.edu/ebola/who-shares-more-details-about-uganda-s-second-ebola-sudan-cluster">Ebola</a> and even a mysterious but <a href="https://www.wired.com/story/race-to-identify-drcs-mystery-illness-slowed-by-us-aid-cuts-democratic-republic-congo-usaid/?utm_brand=wired&amp;utm_social-type=owned&amp;utm_source=twitter&amp;utm_medium=social&amp;utm_campaign=aud-dev">deadly disease in Congo</a>.</p>

<p class="has-text-align-none">The consequences that have been documented so far are <a href="https://www.theguardian.com/global-development/ng-interactive/2025/feb/21/the-impact-has-been-devastating-how-usaid-freeze-sent-shockwaves-through-ethiopia">severe</a> and <a href="https://geographical.co.uk/news/usaid-what-projects-have-already-been-affected-by-aid-cuts">widesweeping</a>, and yet they represent an incomplete tally of how billions of lives and livelihoods will be affected now or in the future. Here is everything we know about the US foreign aid’s global health effects around the world in three charts.</p>

<h2 class="wp-block-heading has-text-align-none">Millions of patients stranded</h2>

<p class="has-text-align-none">Until very recently, USAID worked in 160 countries to spread democracy, reduce poverty, improve health, prevent and contain infectious disease outbreaks and provide food, clean water, and education to rural, underserved, refugee, and conflict-affected communities. In the decades since <a href="https://history.state.gov/milestones/1961-1968/pl-480">President John F. Kennedy established the agency</a> in 1961, USAID became a household name in many countries. US foreign aid in those decades was a critical and <a href="https://www.state.gov/literature-review-about-the-relationship-between-foreign-aid-and-economic-growth/">oft-studied tool of global diplomacy</a>, and one that — until recently — has had <a href="https://www.reuters.com/world/what-is-usaid-why-has-it-become-target-trump-musk-2025-02-03/">consistent bipartisan support</a>.</p>

<p class="has-text-align-none">When it comes to aid, the US is irreplaceable. US donations to the United Nations in 2024 comprised <a href="https://news.un.org/en/story/2025/01/1159486">40 percent</a> of all funds for humanitarian aid. The <a href="https://www.wfp.org/funding/2024">US donated almost half</a> of all global food aid and made huge <a href="https://open.who.int/2022-23/contributors/by-fund-types/cfe?name=United%20States%20of%20America">contributions to the World Health Organization</a> for disease outbreaks and health emergencies.</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2025/03/8cTVq-sub-saharan-africa-was-the-largest-recipient-of-us-health-aid-in-2024-1-1.png?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="" title="" data-has-syndication-rights="1" data-caption="" data-portal-copyright="" />
<p class="has-text-align-none">In all, the US spent more than $10 billion on health aid around the world in 2024. Countries in sub-Saharan Africa received the lion’s share of that aid, but developing countries everywhere have been affected by US funding cuts. Here are some key impacts that the US foreign funding freeze has had so far:</p>

<ul class="wp-block-list">
<li>An estimated <a href="https://geographical.co.uk/news/usaid-what-projects-have-already-been-affected-by-aid-cuts">3.8 million</a> women lost access to contraception globally.</li>



<li>9 million people in Afghanistan — nearly a quarter of the population — will no longer receive US-funded healthcare services .</li>



<li>Nearly 700,000 people in Burkina Faso and Mali have lost access to water, food, or health services.</li>



<li>The World Food Programme, for which the US is <a href="https://www.wfp.org/funding/2025">the largest single donor</a>, has <a href="https://www.jurist.org/news/2025/03/un-world-food-program-closes-southern-africa-office-amid-us-aid-cuts/#:~:text=UN%20World%20Food%20Program%20closes,US%20aid%20cuts%20%2D%20JURIST%20%2D%20News&amp;text=The%20UN%20World%20Food%20Program,administration's%20recent%20foreign%20aid%20cuts.">shut down</a> its operations in South Africa, where 27 million people are at risk of hunger as the country faces its worst drought in decades.</li>



<li>In Nigeria, <a href="https://x.com/DropSiteNews/status/1896792251839238249">25,000</a> extremely malnourished children will no longer be receiving food assistance by April.</li>
</ul>

<p class="has-text-align-none">Perhaps the most important program <a href="https://www.vox.com/future-perfect/402944/pepfar-hiv-donald-trump-elon-musk-global-health">targeted</a> is the President&#8217;s Emergency Plan for AIDS Relief (<a href="https://www.state.gov/pepfar/">PEPFAR</a>). PEPFAR, which provides testing services and treatment to prevent and treat HIV, is credited with saving some <a href="https://www.hiv.gov/federal-response/pepfar-global-aids/pepfar">25 million lives</a>. Although the program was not entirely cancelled, several major contracts were cut or shrunk down considerably. As a result, <a href="https://www.hiv.gov/federal-response/pepfar-global-aids/pepfar#:~:text=Providing%20Life%2DSaving%20Antiretroviral%20Treatment,intervention%20to%20prevent%20HIV%20transmission.">20.6 million people</a>, including almost 600,000 children, are no longer receiving HIV treatment that was previously funded by the US. Experts estimate that <a href="https://www.gastroenterologyadvisor.com/news/hiv-infections-could-skyrocket-without-us-funding/#:~:text=UNAIDS%20Executive%20Director%20Winnie%20Byanyima,of%20his%20America%20First%20agenda.">HIV burden could increase sixfold</a> in the next four years.</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2025/03/oRQgz-before-aid-cuts-the-us-funded-70-percent-of-the-global-hiv-aids-response-2.png?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="Before aid cuts, the US funded 70 percent of the global HIV/AIDS reponse." title="Before aid cuts, the US funded 70 percent of the global HIV/AIDS reponse." data-has-syndication-rights="1" data-caption="" data-portal-copyright="" />
<p class="has-text-align-none">The Trump administration’s dismantling of USAID and other government agencies has been messy. There have been a flurry of <a href="https://www.nytimes.com/interactive/2025/03/05/us/politics/usaid-trump-timeline.html">lawsuits</a> still awaiting court decisions that allege the Trump administration’s actions against USAID and its contractors are unlawful; however, on Monday, a <a href="https://www.reuters.com/world/us/judge-will-not-order-trump-administration-restore-canceled-foreign-aid-contracts-2025-03-11/">federal judge declined to order the administration</a> to restore canceled contracts. </p>

<p class="has-text-align-none">China is already moving into the void. Local media outlets from <a href="https://theannapurnaexpress.com/story/52229/">Nepal</a> to <a href="https://www.lasillavacia.com/silla-nacional/si-se-retira-usaid-de-colombia-los-efectos-politicos-se-sentiran/">Colombia</a> have reported that representatives of the Chinese government have already come forward with offers to expand its assistance in areas from agriculture and disaster relief to health care and poverty alleviation. After <a href="https://www.globaltimes.cn/page/202502/1328827.shtml">floods devastated parts of Madagascar</a>, Chinese officials mounted <a href="https://reliefweb.int/report/madagascar/china-offers-aid-flood-affected-madagascar">their first-ever humanitarian response</a> in the country. Within days, Chinese aid tents lined the Ikopa River. </p>

<p class="has-text-align-none">How much China will aim to capitalize on this opportunity is not yet clear. And while the US foreign aid freeze and cuts have already had enormous repercussions, its full effects won’t be felt in full for months or even years to come. USAID-funded agriculture programs, for instance, were not able to disperse seeds in time for planting, which means that farmers may miss an entire growing season, a spokesperson for a US nonprofit company that receives USAID contracts told me. This will worsen food insecurity and could plunge families into poverty.</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2025/03/DpjAk-us-donations-to-the-un-accounted-for-40-percent-of-all-humanitarian-aid-in-2024-2.png?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="US donations to the UN accounted for 40 percent of all humanitarian aid in 2024" title="US donations to the UN accounted for 40 percent of all humanitarian aid in 2024" data-has-syndication-rights="1" data-caption="" data-portal-copyright="" />
<p class="has-text-align-none">In other places, time-sensitive mosquito control activities — like spraying insecticide to kill larva before they become mosquitos — were missed, which will likely result in an explosion of dengue, malaria, and other mosquito-borne infectious diseases in a few months. </p>

<p class="has-text-align-none">A lack of US funding for polio eradication efforts will likely lead to an <a href="https://www.usnews.com/news/health-news/articles/2025-03-04/the-life-saving-programs-disappearing-as-a-result-of-the-usaid-funding-cuts">additional 200,000 polio cases a year</a>. Some <a href="https://www.medrxiv.org/content/10.1101/2025.03.04.25323340v1.full.pdf">10.6 million cases of tuberculosis</a> and 2.2 million deaths will not be prevented in the void of US foreign aid funding. </p>

<p class="has-text-align-none">If you’re an optimist, then you might hold on to a bit of hope that some of these programs might be restored, that the bipartisan consensus that once supported foreign aid can be rebuilt. But as the days go by, that seems increasingly unlikely. The hard reality is that the Trump administration’s actions have left massive gaps in global aid that will ultimately be measured in lives lost.</p>
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					</entry>
			<entry>
			
			<author>
				<name>Jessica Craig</name>
			</author>
			
			<title type="html"><![CDATA[Will warning labels on ultra-processed foods make America healthy again?]]></title>
			<link rel="alternate" type="text/html" href="https://www.vox.com/future-perfect/402470/ultra-processed-foods-labels-fda-maha" />
			<id>https://www.vox.com/?p=402470</id>
			<updated>2025-03-04T16:55:38-05:00</updated>
			<published>2025-03-05T08:30:00-05:00</published>
			<category scheme="https://www.vox.com" term="Future Perfect" /><category scheme="https://www.vox.com" term="Health" /><category scheme="https://www.vox.com" term="Public Health" />
							<summary type="html"><![CDATA[After decades of lobbying, the US government has finally started taking action to warn consumers about the hazards of ultra-processed foods: your potato chips, granola bars, cereal, frozen pizza, even many types of store-bought bread.&#160; As I reported last year, there is mounting scientific evidence linking such ultra-processed foods, or UPFs, to disorders that range [&#8230;]]]></summary>
			
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<img alt="A woman pushes a grocery cart down a brightly lit store aisle." data-caption="" data-portal-copyright="﻿Jeffrey Greenberg/Universal Images Group via Getty Images" data-has-syndication-rights="1" src="https://platform.vox.com/wp-content/uploads/sites/2/2025/03/gettyimages-1806582759.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
	<figcaption>
		</figcaption>
</figure>
<p class="has-text-align-none">After decades of lobbying, the US government has finally started taking action to warn consumers about the hazards of ultra-processed foods: your potato chips, granola bars, cereal, frozen pizza, even many types of store-bought bread.&nbsp;</p>

<p class="has-text-align-none">As I <a href="https://www.vox.com/future-perfect/370257/ultra-processed-food-obesity-disease-depression-anxiety">reported</a> last year, there is mounting scientific evidence linking such ultra-processed foods, or UPFs, to disorders that range from obesity, diabetes, and high blood pressure to depression, anxiety, and autoimmune disorders. Precisely what is classified as a UPF isn’t perfect and the category can sometimes be too broad, as my colleague Marina Bolotnikova <a href="https://www.vox.com/future-perfect/391795/ultra-processed-foods-science-vegan-meat-rfk-maha">explained</a> in December, but there’s still a growing consumer <a href="https://www.futureoffood.institute/portfolio-en/articles/ultra-processed-foods/">desire</a> for clarity about what we’re buying and eating.&nbsp;</p>

<div class="wp-block-vox-media-highlight vox-media-highlight">
<h2 class="wp-block-heading">This story was first featured in the <a href="https://www.vox.com/pages/future-perfect-newsletter-signup">Future Perfect newsletter</a>.</h2>



<p class="has-text-align-none">Sign up <a href="https://www.vox.com/pages/future-perfect-newsletter-signup">here</a> to explore the big, complicated problems the world faces and the most efficient ways to solve them. Sent twice a week.</p>
</div>

<p class="has-text-align-none">Earlier this year, in an effort&nbsp;to combat the rising burden of these chronic diseases, the US Food and Drug Administration (FDA) under former President Joe Biden <a href="https://www.fda.gov/news-events/press-announcements/fda-proposes-requiring-glance-nutrition-information-front-packaged-foods">proposed</a> a new policy that would require food producers to add new nutrition labels to the front of most packaged foods, warning consumers about the high fat, sodium, and sugar content typically found in UPFs. New <a href="https://www.cnn.com/2025/02/13/politics/rfk-jr-senate-confirmation-vote/index.html">Secretary</a> of Health and Human Services Robert Kennedy Jr., will likely continue this work; he has <a href="https://www.minnpost.com/race-health-equity/2025/02/a-closer-look-at-rfk-jr-s-stance-on-ultra-processed-foods/">called</a> UPFs “<a href="https://time.com/7211678/rfk-jr-ultra-processed-foods-ban/">poison</a>,” and has promised reform.</p>

<p class="has-text-align-none">A handful of <a href="https://www.annualreviews.org/docserver/fulltext/nutr/41/1/annurev-nutr-111120-094932.pdf?expires=1740681859&amp;id=id&amp;accname=guest&amp;checksum=DD96AFA25E153778F94A1B04EE8C96F4">countries</a> in Latin America and Europe have already introduced similar front-of-package nutrition labels. In 2020, <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9067899/#:~:text=In%202020%2C%20Mexico%20adopted%20new,with%20the%20statement%20%E2%80%9Cavoid%2Fnot">Mexico</a> passed a law that required a variety of warning labels on all packaged foods and beverages; the labels include black stop-sign shaped figures that indicate if the product has excessive sugar, sodium, or saturated fats. Chile was the first country to pass such a law back in <a href="https://www.tandfonline.com/doi/full/10.1080/23288604.2020.1753159">2012</a>. The UK has a similar <a href="https://thecritic.co.uk/ultra-processed-arguments/">system</a> in place, but companies are not legally required to add the warnings to their products.&nbsp;</p>

<p class="has-text-align-none">The US may be late to the nutrition-warning game, but the good news is that similar efforts in other places have been effective in raising consumer awareness of UPF’s nutritional hazards and in pressuring manufacturers to make healthier products.&nbsp;</p>

<p class="has-text-align-none">These labels enable consumers to make more informed decisions about what they eat without infringing on their rights to eat what they want. But while nutrition experts have welcomed the FDA’s proposed policy change, the addition of warning labels to packaged goods hasn’t been shown to reduce the very real burden of chronic diseases. For that, we’ll need systemic change.&nbsp;</p>

<h2 class="wp-block-heading has-text-align-none"><strong>Are warning labels effective?</strong></h2>

<p class="has-text-align-none">Much of the real-world evidence describing the impact of front-of-package nutrition labels comes from Latin American countries. They have long been pioneers in UPF <a href="https://www.truehealthinitiative.org/council_member/carlos-a-monteiro/">research</a> and regulation, in part because of their high burden of chronic diseases linked to UPF consumption but also because of how the spread of UPFs <a href="https://novaramedia.com/2024/10/14/latin-america-is-leading-the-charge-against-ultra-processed-food/">pushed out traditional foods</a>, explained <a href="https://www.researchgate.net/profile/Vanessa-Couto-3">Vanessa Couto</a>, a public health nutrition researcher at the University of São Paulo in Brazil.&nbsp;</p>

<p class="has-text-align-none">In some 30 Latin American <a href="https://www.thelancet.com/pdfs/journals/lanam/PIIS2667-193X%2822%2900217-4.pdf">countries</a> that have added front-of-package nutrition warnings, public health researchers have found that well-designed labels can help consumers be more informed about what’s in the products they buy. “We see people shifting toward healthier options, avoiding less healthy options,” explained <a href="https://sph.unc.edu/adv_profile/marissa-g-hall-phd/">Marissa Hall</a>, an assistant professor at the University of North Carolina Gillings School of Global Public Health. “We also see where labeling can help people understand what&#8217;s in their food and which products are high in nutrients of concern.”</p>

<p class="has-text-align-none">One 2024 <a href="https://journals.plos.org/plosmedicine/article?id=10.1371/journal.pmed.1004463">study</a> of almost 3,000 households in Chile found that consumers purchased significantly fewer products labeled as high in sugar, calories, sodium, and fat, amounting to an estimated 36.8 percent reduction in sugar consumption, a 23 percent reduced calorie intake, a 21.9 percent reduction in sodium, and a 15.7 percent drop in saturated fat consumption.&nbsp;</p>

<p class="has-text-align-none">But not all studies report these impacts. Another <a href="https://ijbnpa.biomedcentral.com/articles/10.1186/s12966-024-01664-w">study</a> in Brazil, found that while a “Warning: ultra-processed food” label significantly improved the ability of consumers to identify what products were UPF, it did not influence their purchasing intentions or perceptions of healthfulness.</p>

<p class="has-text-align-none">The other benefit of nutrition labels on packaged foods is that it creates a market pressure for UPF manufacturers to make healthier foods, Hall explained. After Chile implemented its warning label law, the proportion of UPF products that were high in sugar dropped from <a href="https://www.annualreviews.org/docserver/fulltext/nutr/41/1/annurev-nutr-111120-094932.pdf?expires=1741101065&amp;id=id&amp;accname=guest&amp;checksum=99D3C8EDCFEB752FDB27E78C75F3B9A9">80 to 60 percent</a> while products high in sodium dropped from 74 to 27 percent.&nbsp;</p>

<p class="has-text-align-none">Similar schemes in New Zealand and the Netherlands that allowed companies to display a logo indicating a product’s healthfulness if it met certain nutritional requirements also prompted companies to swiftly reformulate products. One study found that there was a <a href="https://www.annualreviews.org/docserver/fulltext/nutr/41/1/annurev-nutr-111120-094932.pdf?expires=1741101065&amp;id=id&amp;accname=guest&amp;checksum=99D3C8EDCFEB752FDB27E78C75F3B9A9">61 percent reduction</a> of salt in cereal products in New Zealand while 20 percent of products were reformulated in the Netherlands after the labeling schemes were introduced.&nbsp;</p>

<p class="has-text-align-none">The FDA’s <a href="https://www.fda.gov/news-events/press-announcements/fda-proposes-requiring-glance-nutrition-information-front-packaged-foods">proposed</a> nutritional labels aren’t the same as those used in Latin America. In Chile and Mexico, companies are required to use bold, black stop-sign shaped icons on the front of a package, which communicate whether the product is high in fat, sugar, or sodium. If a package has three stop signs, then it is high in all three.&nbsp;</p>

<p class="has-text-align-none">The FDA’s <a href="https://www.fda.gov/news-events/press-announcements/fda-proposes-requiring-glance-nutrition-information-front-packaged-foods">version</a> consists of small, black-and-white boxes similar to existing nutritional facts boxes that already appear on the back of packaged foods, though they’ll be placed on the front. These boxes will indicate if a product contains low, medium, or high levels of saturated fat, sodium, and added sugar.&nbsp;</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2025/03/front_label_16x9_45e96a.png?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="" title="" data-has-syndication-rights="1" data-caption="Food and Drug Administration’s proposed front-of-package nutritional labels. /FDA" data-portal-copyright="" /><img src="https://platform.vox.com/wp-content/uploads/sites/2/2025/03/Example-of-a-front-of-package-FoP-nutrient-warning-label-system-from-Chile-In-English_777730.png?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="" title="" data-has-syndication-rights="1" data-caption="Front-of-packaging warning labels used in Chile indicating that foods are high in calories, sugars, salt and saturated fat/ Chilean Ministry of Health" data-portal-copyright="" />
<p class="has-text-align-none">So the US labels could show that a product is high in salt but low in sugar and then leave it to the consumer to decide if that is good or bad. Contextualizing percentages can be helpful, but comparing such trade-offs isn&#8217;t always intuitive.&nbsp;“I&#8217;m concerned that it might be confusing for people to understand an overall product’s healthfulness when they&#8217;re making sense of all these different nutrients,” Hall said.&nbsp;</p>

<p class="has-text-align-none">Others have been far more critical of the FDA’s proposed nutrition labels. Sen. Bernie Sanders <a href="https://vermontbiz.com/news/2025/january/14/sanders-statement-fdas-weak-proposed-front-package-nutrition-labels">said</a> the labels were “pathetically weak and must be substantially improved.” He suggested that UPF warning labels should more resemble the FDA-mandated warning <a href="https://www.fda.gov/tobacco-products/labeling-and-warning-statements-tobacco-products/cigarette-labeling-and-health-warning-requirements#:~:text=For%20cigarette%20cartons%2C%20the%20required,cellophane%20or%20other%20clear%20wrapping.">labels</a> on cigarettes that explicitly state smoking causes fatal lung disease, heart disease, cataracts, bladder cancer, and a list of other conditions. (Earlier this year, a federal judge in Texas <a href="https://www.reuters.com/legal/us-judge-blocks-fda-graphic-warning-label-requirement-cigarettes-2025-01-14/">blocked</a> an FDA mandate to require graphic warnings of smoking’s health risks.)</p>

<p class="has-text-align-none">While warning labels improved consumer awareness in studies, this hasn’t translated into overall improved health outcomes. Chile introduced nutrition warning labels in 2012, but obesity rates have continued to rise from about <a href="https://www.statista.com/statistics/1468754/overweight-obesity-prevalence-chile/">68 percent</a> in 2010 to 79 percent in 2022. The Chilean government even introduced other measures to reduce UPF consumption; for example, by increasing the tax on sugary beverages from 13 percent to <a href="https://www.bcn.cl/leychile/navegar?idNorma=1067194&amp;idParte=&amp;idVersion=2014-10-01">18 percent</a> in 2014. </p>

<p class="has-text-align-none">In Mexico, which introduced labeling mandates in 2020, childhood obesity <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9433666/#:~:text=In%20school%2Dage%20children%2C%20the,2021%20(2%E2%80%934).">rates</a> dropped slightly from 38.2 percent in 2020 to 37.3 percent the following year, but the number of people with diabetes increased from <a href="https://www.scielo.org.mx/scielo.php?script=sci_arttext&amp;pid=S0036-36342021000600725#:~:text=The%20total%20prevalence%20of%20diabetes,were%20associated%20with%20better%20control.">15.7 percent</a> in 2020 to 18.2 percent <a href="https://www.thelancet.com/journals/lanam/article/PIIS2667-193X(24)00059-0/fulltext">in 2022</a>.</p>

<p class="has-text-align-none">It may simply be too soon for public health officials to observe improvements in obesity and other chronic disease rates. What’s clear is that we will need more than nutrition labels to create a food environment that allows everyone to eat healthy nutritious foods.&nbsp;</p>

<h2 class="wp-block-heading has-text-align-none"><strong>What more needs to be done to “make America healthy again</strong>”</h2>

<p class="has-text-align-none">While studies in Latin American countries have reported that front-of-package warning labels on UPFs are effective at improving awareness among consumers, this is really only one small step in the right direction. To actually reduce UPF consumption and improve health, we would need true systemic change.&nbsp;</p>

<p class="has-text-align-none">More than <a href="https://www.socialpolicylab.org/post/grow-your-blog-community#:~:text=New%20analysis%20from%20the%20Association,Americans%20struggles%20to%20eat%20daily.">20 million</a> Americans live in food deserts without consistent access to healthy foods. These areas tend to be <a href="https://www.newrootsinstitute.org/articles/food-deserts#:~:text=Low%20Income,than%20its%20lack%20of%20availability.">low-income and rural</a> communities where there is a shortage of food retailers and a lack of transportation to get there. Unprocessed or minimally processed foods are, on average, more than <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7551888/#:~:text=A%20recent%20study%20from%20the,1.45%2F100%20kcal).">twice as expensive</a> as UPFs per calorie, according to one study.&nbsp;</p>

<p class="has-text-align-none">True success would require improving health education in schools, raising the quality of school lunches, and ensuring that everyone can actually afford fresh, healthy foods — a tall order in a country that has long prioritized profits over health and safety.</p>

<p class="has-text-align-none">It remains unclear what might happen to the FDA’s proposed legislation under the Trump administration. Kennedy seems keen to take on UPFs as part of his Make America Healthy Again crusade — he currently <a href="https://www.cbsnews.com/news/rfk-jr-weighing-fda-crackdown-on-food-additives-under-trump/">wants</a> the FDA to ban certain additives, dyes, and chemicals currently used in UPF.&nbsp;</p>

<p class="has-text-align-none">What do experts recommend? Aside from mandating warning labels on packaged goods, the FDA needs to also regulate other marketing claims that UPF companies make on their products, Hall argued. For instance, many products claim to be “100 percent all natural,” which Hall’s research has shown makes many consumers incorrectly assume the product has no added sugars. But this can be false because there is no standard or even legal definition of “natural.”</p>

<p class="has-text-align-none">Nutritional labels on UPF, along with other policy changes such as banning certain food dyes, is just the beginning. “It takes small steps,” Baker said. And while she and many are hopeful that Kennedy’s “food is medicine” outlook will usher in change, many fear that the Trump administration’s federal staff and budget cuts will hamper efforts.&nbsp;</p>
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			<author>
				<name>Jessica Craig</name>
			</author>
			
			<title type="html"><![CDATA[What happens to the money when I round up at the register?]]></title>
			<link rel="alternate" type="text/html" href="https://www.vox.com/explain-it-to-me/400992/charity-round-ups-checkout-campaigns" />
			<id>https://www.vox.com/?p=400992</id>
			<updated>2025-02-27T17:59:17-05:00</updated>
			<published>2025-02-26T08:00:00-05:00</published>
			<category scheme="https://www.vox.com" term="Explain It to Me" /><category scheme="https://www.vox.com" term="Future Perfect" />
							<summary type="html"><![CDATA[Vox reader Ben Kutcher asks: What happens to the money when I round up at the register? Are these real charities? Who gets credit for the donation? Is there some taxable benefit to companies that offer this? Do they have to provide transparency reports? If you’ve ever been at a grocery store checkout counter and [&#8230;]]]></summary>
			
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<img alt="A customer pays for groceries at the check out counter" data-caption="A customer pays for groceries at the check out counter in Drancy, France, on September 11, 2024. | Ludovic Marin/AFP via Getty Images" data-portal-copyright="Ludovic Marin/AFP via Getty Images" data-has-syndication-rights="1" src="https://platform.vox.com/wp-content/uploads/sites/2/2025/02/gettyimages-2170643243.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
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	A customer pays for groceries at the check out counter in Drancy, France, on September 11, 2024. | Ludovic Marin/AFP via Getty Images	</figcaption>
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<p class="has-text-align-none"><em>Vox reader Ben Kutcher</em><em> asks: What happens to the money when I round up at the register? Are these real charities? Who gets credit for the donation? Is there some taxable benefit to companies that offer this? Do they have to provide transparency reports?</em></p>

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<p class="has-text-align-none">If you’ve ever been at a grocery store checkout counter and the cashier asked you to round up your purchase for charity, you’ve probably asked yourself the same questions. Round-up charity campaigns were first introduced about <a href="https://www.npr.org/2024/03/10/1236458377/charity-roundup-donations-stores-fundraising">15 years</a> ago and have since become omnipresent. In 2022, 77 of the most successful of these initiatives raised more than <a href="https://engageforgood.com/guides/point-of-sale-fundraising/">$749 million</a>, more than double the amount raised in 2012.&nbsp;</p>

<p class="has-text-align-none">These types of charity campaigns are pretty simple. Charities <a href="https://dobetter.esade.edu/en/raising-funds-cent-impact-round-up-donations">partner</a> with businesses — your local grocery store, gas station, or favorite restaurant — which then ask their customers to round up their purchase total to the nearest dollar. Those extra few cents go toward the fundraiser. The retailer typically collects these small donations over a set period of time and then transfers that lump sum of money to the charity.&nbsp;</p>

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<p class="has-text-align-none">The newsletter is part of Vox’s <a href="https://www.vox.com/explain-it-to-me">Explain It to Me</a>, where we tackle a question from our audience and deliver a digestible explainer from one of our journalists. Have a question you want us to answer? Ask us <a href="http://www.vox.com/ask-vox">here</a>.</p>
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<p class="has-text-align-none">The <span>round-up campaigns have proven to be pretty successful.&nbsp;<a href="https://www.binghamton.edu/news/story/4945/more-than-half-of-americans-give-to-charity-at-checkout-survey-shows" target="_blank">More than half</a>&nbsp;of Americans are willing to round up and fork over a few cents. A 2018&nbsp;<a href="https://myscp.onlinelibrary.wiley.com/doi/abs/10.1002/jcpy.1064" target="_blank">study</a>&nbsp;found that the round-up approach is more successful than other,</span> more traditional types of fundraising, even when customers are asked to donate about the same amount of money as they would give by rounding up their purchase total.&nbsp;</p>

<p class="has-text-align-none">At the same time, however, the uptick in gas stations, restaurants, and supermarkets asking you to round up your purchase for charity has started to <a href="https://www.wsj.com/personal-finance/donation-store-checkout-charity-tipping-a5282806">frustrate</a> some customers. These requests usually don’t come with a whole lot of information about who is benefiting and how much of your donation will actually reach the charity, which makes many people hesitant to donate spontaneously. (Not to mention, there are concerns about whether donation round-ups are just a farce for businesses to get tax breaks.)&nbsp;</p>

<p class="has-text-align-none">Here is everything you need to know about these campaigns so you can make an informed decision the next time you’re asked to round up for charity.&nbsp;</p>

<h2 class="wp-block-heading has-text-align-none">Who gets the tax benefit? </h2>

<p class="has-text-align-none">One of the biggest controversies surrounding round-up campaigns is who reaps the tax benefits: the customer who rounds up or the business running the fundraiser? </p>

<p class="has-text-align-none">There is a lot of <a href="https://taxpolicycenter.org/taxvox/who-gets-tax-benefit-those-checkout-donations-0">misinformation</a> swirling around out there on social media, but tax experts have set the record straight: The customer who donates the money gets the tax benefit.</p>

<p class="has-text-align-none">When you opt to round up your purchase and donate to charity, the business where you make the transaction is merely serving as a go-between. They pool their customers’ funds and then hand them off to the charity, Renu Zaretsky, a writer at the Urban-Brookings Tax Policy Center, told <a href="https://apnews.com/article/fact-checking-000329849244">the Associated Press</a>. The business is just a holding agent and cannot report the donated funds as a charitable donation.&nbsp;</p>

<p class="has-text-align-none">Walmart launched a round-up campaign in 2022 that allows customers to pick a verified charity to donate to. Customer donations are <a href="https://www.walmart.org/content/dam/walmart-org/documents/what-we-do/strengthening-community/spark-good/spark-good-getting-started/spark-good-round-up-how-to-guide.pdf">sent directly</a> to a third-party platform where nonprofits can track the campaign and receive their funds. Nonprofits such as <a href="https://operationhomefront.org/">Operation Homefront</a>, which raises money to support military families, have raised <a href="https://operationhomefront.org/walmart-com-customers-round-up-for-oh/#:~:text=Over%20the%20past%20two%20years,struggling%20to%20make%20ends%20meet.">millions</a> through this campaign. Sometimes, Walmart even matches donations, meaning if a customer donates 20 cents, the store does too. (Now when stores match donations like this, they are the ones donating and receive a tax benefit.)&nbsp;</p>

<p class="has-text-align-none">The customer reaps all the tax benefits of the donation so long as you include it on your tax form, which most people don’t. Read more about how to do that <a href="https://www.vox.com/even-better-guide-to-tax-season">here</a>.</p>

<p class="has-text-align-none">While stores cannot write off the donations they receive from customers who round up their purchases, there is another similar type of <a href="https://apnews.com/article/fact-checking-000329849244">fundraiser</a> out there that does allow businesses to gain a tax benefit. When businesses elect to donate a portion of their sales to a charity — meaning the business is taking some of their regularly earned income and giving it to charity — then they can write off that expense in their taxes. But this is not the same as a round-up campaign.&nbsp;&nbsp;</p>

<h2 class="wp-block-heading has-text-align-none">How transparent are companies about how much they raise?</h2>

<p class="has-text-align-none">Generally, for-profit companies are not legally required to disclose how much money they raise for charities during round-up campaigns or other fundraising efforts. <a href="https://www.councilofnonprofits.org/running-nonprofit/administration-and-financial-management/commercial-co-ventures-and-cause-related">Less than half</a> of the states in the US have laws in place that address charitable promotions, and these laws vary drastically in terms of transparency, record-keeping, and advertising. Some states — such as California, Massachusetts, and New York — have more stringent laws.&nbsp;</p>

<p class="has-text-align-none">Short of legally binding requirements, many reputable companies still publish annual donation reports or corporate social responsibility reports that detail how much they may have raised and where that money has gone. But, again, the quality of these reports varies from company to company, as my colleague Sam Delgado has <a href="https://www.vox.com/future-perfect/357989/worker-driven-social-responsibility-corporate-ethics-consumers">previously written</a>.</p>

<p class="has-text-align-none">One of the biggest questions surrounding round-up campaigns and other charitable donations is how much of the donation actually goes to the cause versus administrative costs or overhead. Although there is no universal legal limit on how much of a round-up donation can go to cover fees, some states regulate this or require charities to disclose where exactly donations go. Charity watchdogs recommend that at least <a href="https://warrenaverett.com/insights/nonprofit-ratios/?utm_source=chatgpt.com">65 percent to 70 percent</a> of total funds raised go toward program expenses. (Most charities need to use some donations to cover bare minimum costs such as for staff, advertising, or office space.)&nbsp;</p>

<p class="has-text-align-none">Rather than worry about how Petco is interfacing with a local animal shelter, perhaps the better move is to get familiar with the charities you do believe in beforehand. It&#8217;s hard to evaluate whether to give money when you&#8217;re just trying to get home before your ice cream melts. Evaluating certain causes through donation reports or a charity watchdog — such as <a href="https://www.charitywatch.org/">CharityWatch</a> or <a href="https://www.charitynavigator.org/">Charity Navigator</a>&nbsp;—&nbsp;ahead of time might spare you some distress. Here are Future Perfect&#8217;s recommended charities for <a href="https://www.vox.com/future-perfect/2019/12/2/20976180/climate-change-best-charities-effective-philanthropy">climate</a>, <a href="https://www.vox.com/future-perfect/2019/12/3/20992185/animal-welfare-best-charities-factory-farming">animals</a>, and <a href="https://www.vox.com/future-perfect/388262/giving-tuesday-guide-global-health-malaria-givewell">health</a>.</p>

<p class="has-text-align-none">And yes, even a few cents can go a long way!</p>

<p class="has-text-align-none"><em>This story was featured in the Explain It to Me newsletter. Sign up&nbsp;</em><a href="https://www.vox.com/pages/explain-it-to-me-newsletter-sign-up"><em>here</em></a><em>.</em>&nbsp;<em>For more from Explain It to Me,&nbsp;</em><a href="https://link.chtbl.com/explainit?sid=site"><em>check out the podcast</em></a><em>.</em></p>

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			<entry>
			
			<author>
				<name>Jessica Craig</name>
			</author>
			
			<title type="html"><![CDATA[I work in global health. Trump ditching the World Health Organization might be the wake-up call it needs.]]></title>
			<link rel="alternate" type="text/html" href="https://www.vox.com/future-perfect/399581/trump-who-world-health-organization-public-health" />
			<id>https://www.vox.com/?p=399581</id>
			<updated>2025-02-18T15:00:38-05:00</updated>
			<published>2025-02-17T06:00:00-05:00</published>
			<category scheme="https://www.vox.com" term="Donald Trump" /><category scheme="https://www.vox.com" term="Explainers" /><category scheme="https://www.vox.com" term="Future Perfect" /><category scheme="https://www.vox.com" term="Health" /><category scheme="https://www.vox.com" term="Politics" /><category scheme="https://www.vox.com" term="Public Health" /><category scheme="https://www.vox.com" term="World Politics" />
							<summary type="html"><![CDATA[Shortly after his inauguration, President Donald Trump took a set of thick, black permanent markers and signed a sweeping set of executive orders that took aim at everything from immigration and gender to TikTok and climate change. One of his first moves was to withdraw the US from the World Health Organization (WHO), the United [&#8230;]]]></summary>
			
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<img alt="WHO sign" data-caption="" data-portal-copyright="" data-has-syndication-rights="1" src="https://platform.vox.com/wp-content/uploads/sites/2/2025/02/gettyimages-2197464483.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
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<p class="has-text-align-none">Shortly after his inauguration, President Donald Trump took a set of thick, black permanent markers and signed a sweeping set of executive orders that took aim at everything from <a href="https://www.vox.com/politics/396083/trump-executive-order-immigration-border-birthright-citizenship">immigration</a> and <a href="https://apnews.com/article/trump-transgender-transition-executive-order-301e4130233b411311978f66f455f1c4">gender</a> to <a href="https://apnews.com/article/trump-tiktok-ban-executive-order-50df1f96c25576762b65e24b63ce61eb">TikTok </a>and <a href="https://www.vox.com/climate/395897/trump-executive-orders-climate-paris-agreement-oil-gas">climate change</a>. One of his first moves was to <a href="https://www.whitehouse.gov/presidential-actions/2025/01/withdrawing-the-united-states-from-the-worldhealth-organization/">withdraw</a> the US from the <a href="https://www.who.int/about">World Health Organization</a> (WHO), the United Nations’ global health agency responsible for safeguarding and promoting health around the world since 1948.&nbsp;</p>

<p class="has-text-align-none">The US is one of the WHO’s biggest funders, so any shortage of financial and political support will likely have major ramifications for global health efforts like eliminating <a href="https://www.who.int/activities/eliminating-malaria">malaria</a>, improving access to high-quality health care, and reducing <a href="https://www.who.int/news-room/fact-sheets/detail/maternal-mortality">maternal mortality</a>. While that may not directly matter to rich countries like the US that have the means to address their own health challenges, one of the WHO’s most important <a href="https://apps.who.int/gb/bd/pdf_files/BD_49th-en.pdf">jobs</a> is to help coordinate the international response to pandemics and outbreaks — events that can threaten everyone, regardless of borders, as we <a href="https://www.vox.com/24151110/bird-flu-h5n1-pandemic-treaty-prevention-response">learned during Covid-19</a>.&nbsp;</p>

<p class="has-text-align-none">To Trump and <a href="https://oversight.house.gov/release/hearing-wrap-up-the-world-health-organizations-flawed-framework-must-be-reformed/">his supporters</a>, the WHO’s perceived failure on that job is one of the biggest reasons why the US should withdraw. Chief among Trump’s complaints are the WHO’s <a href="https://www.heritage.org/global-politics/commentary/stuck-failure-the-who">mishandling</a> of the <a href="https://foreignpolicy.com/2020/05/27/who-health-china-coronavirus-tedros/">Covid-19</a> pandemic and <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7122988/">other</a> global health crises, its failure to reform, and its inability to demonstrate independence from powerful but authoritarian WHO member states, namely China.</p>

<p class="has-text-align-none">Trump’s decision has engendered <a href="https://publichealth.berkeley.edu/news-media/opinion/withdrawal-from-who-could-bring-tragedy">plenty of criticism</a>, including from experts who <a href="https://www.nytimes.com/2025/01/29/health/who-us-withdrawal.html">argue</a> that the US could suffer if it loses access to vital WHO data on outbreaks. Still, the WHO is far from perfect, and even before Trump, <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7122988/.">scientists</a>, <a href="https://www.chathamhouse.org/2014/05/whats-world-health-organization">think tanks</a>, and <a href="https://www.europarl.europa.eu/thinktank/en/document/EPRS_BRI(2020)651910">government bodies</a> have been pointing out the WHO’s <a href="https://theindependentpanel.org/wp-content/uploads/2021/05/COVID-19-Make-it-the-Last-Pandemic_final.pdf">myriad</a> <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7480991/">problems</a>, from the lack of term limits for senior leadership to its massive budget for headquarters staff who are paid additional stipends (around $5,000 to $7,000 per month) to cover the cost of living in Geneva, one of the world’s <a href="https://fortune.com/europe/2024/10/02/most-expensive-cities-to-live-in-switzerland/#:~:text=Geneva%20is%20the%20second%20Swiss,would%20cost%20more%20than%20%24124.">most expensive</a> cities.&nbsp;</p>

<p class="has-text-align-none">I’ve seen the inefficiencies and mismanagement first hand: In my almost 10-year career as a global health epidemiologist, I have interacted with the WHO on many occasions, including, at times, coordinating with them to respond to disease outbreaks in Africa. Like Trump, my biggest complaint is that the organization has shown it is loath to reflect on and address its deficiencies — deficiencies that matter hugely when it has been given the monumental responsibility of safeguarding the world’s health. There has always been some intangible and unspoken sense that the WHO cannot be wrong and cannot be questioned, even after it was clear that it <a href="https://theindependentpanel.org/wp-content/uploads/2021/05/COVID-19-Make-it-the-Last-Pandemic_final.pdf">bungled certain aspects</a> of the Covid-19 pandemic.&nbsp;</p>

<p class="has-text-align-none">But while the WHO is far from perfect, many of its flaws are symptoms of more fundamental challenges that go beyond how it is governed. Balancing the need to respond to international health threats while respecting national sovereignty means cooperation is a fine line — and it&#8217;s one that&#8217;s becoming harder for the agency to walk.</p>

<p class="has-text-align-none">For the WHO to survive, it needs to improve. And for the US to have the best chances of protecting itself from future global health emergencies — especially as the Trump administration also <a href="https://www.vox.com/future-perfect/397399/usaid-omb-purge-government-agency-spending-leave">works to dismantle</a> the United States Agency for International Development, another key player in global health and development — it still needs the WHO. But it needs a better one.</p>

<h2 class="wp-block-heading has-text-align-none"><strong>What Trump gets right — and wrong — about WHO&nbsp;</strong></h2>

<p class="has-text-align-none">In his <a href="https://www.whitehouse.gov/presidential-actions/2025/01/withdrawing-the-united-states-from-the-worldhealth-organization/">executive order</a>, Trump reiterated many of the same issues he raised five years ago when he <a href="https://x.com/realDonaldTrump/status/1262577580718395393/photo/1">first threatened</a> to withdraw from the WHO.&nbsp;</p>

<p class="has-text-align-none">One of Trump’s biggest complaints was that the agency was too slow to alert the world of an emerging health threat in China and to move to contain its spread. Local newspapers had been reporting that a mysterious illness was <a href="https://health.ucsd.edu/news/press-releases/2021-03-18-novel-coronavirus-circulated-undetected-months-before-first-covid-19-cases-in-wuhan-china/">spreading around Wuhan as early as November 17, 2019</a>, a fact <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7166825/">backed up by genetic analysis</a>.&nbsp;</p>

<p class="has-text-align-none">But Chinese health authorities didn’t alert the WHO — which the country was <a href="https://www.cdc.gov/nndss/what-is-case-surveillance/international-health-regulations.html#:~:text=International%20Health%20Regulations%20(IHR)%20focus,role%20to%20carry%20out%20IHR.">required</a> to do under a legal framework called the <a href="https://www.who.int/health-topics/international-health-regulations#tab=tab_1">International Health Regulations</a> — to a spate of patients with an unknown pneumonia-like disease until <a href="https://www.who.int/emergencies/disease-outbreak-news/item/2020-DON229">December 31</a>. By then, valuable time to contain the disease had been lost, though it is Beijing, not WHO, that is largely at fault for this lag.&nbsp;</p>

<p class="has-text-align-none">Still, while the WHO has limited if any power to compel China or any other country to act, the body should have been more proactive in November and December.&nbsp;</p>

<p class="has-text-align-none">“WHO has country offices, WHO has relationships with Ministries of Health. I would argue they certainly should have been aware this was happening,” said <a href="https://dean.sph.brown.edu/dean">Ashish Jha</a>, the dean of Brown University’s School of Public Health and the White House Covid-19 response coordinator during the Biden administration. “It was showing up in a lot of media, social media, and they should have pushed the government to say, what is this? What is going on here, and why don&#8217;t we know more about it?”&nbsp;</p>

<p class="has-text-align-none">Within <a href="https://www.who.int/emergencies/diseases/novel-coronavirus-2019/interactive-timeline#event-0">five days</a> of learning about the unusual cases in China, the WHO had alerted its member states. But the WHO’s Director-General Tedros Adhanom Ghebreyesus traveled to China and, instead of confronting the government about its obfuscation, <a href="https://www.washingtonpost.com/world/asia_pacific/chinese-officials-note-serious-problems-in-coronavirus-response-the-world-health-organization-keeps-praising-them/2020/02/08/b663dd7c-4834-11ea-91ab-ce439aa5c7c1_story.html">heralded</a> Beijing’s response to the outbreak. And then the WHO consistently parrotted inaccurate information from the Chinese government — namely that the virus was not spreading from person to person — to the rest of the world for weeks.&nbsp;</p>

<p class="has-text-align-none">While the WHO <a href="https://www.who.int/news-room/detail/30-01-2020-statement-on-the-second-meeting-of-the-international-health-regulations-(2005)-emergency-committee-regarding-the-outbreak-of-novel-coronavirus-(2019-ncov)">proclaimed</a> Covid-19 a public health emergency in late January, the messaging from the highest levels of WHO in those early months, when officials believed it was still possible that Covid could be contained, was too often confusing.&nbsp;&nbsp;</p>

<p class="has-text-align-none">“For the moment, we are not witnessing sustained and intensive community transmission of this virus, and we are not witnessing large-scale severe disease or death,” Ghebreyesus said during a <a href="https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-the-mission-briefing-on-covid-19---26-february-2020">briefing</a> in late February. That was simply untrue. By that time, China had reported almost 80,000 cases and nearly 3,000 deaths from Covid-19, while 37 other countries were also reporting cases and deaths.&nbsp;</p>

<p class="has-text-align-none">It also took the WHO <a href="https://www.nature.com/articles/d41586-022-00925-7">two years</a>, until late <a href="https://www.statnews.com/2024/04/18/covid-airborne-transmission-disease-who-expanded-definition/#:~:text=Even%20as%20evidence%20grew%20that,was%20airborne%20until%20late%202021.">2021</a>, to finally acknowledge that Covid-19 was airborne, despite the mountain of evidence that scientists had amassed just <a href="https://www.washingtonpost.com/world/europe/coronavirus-airborne-spread-world-health-organization/2020/07/05/9de19c38-bed8-11ea-b4f6-cb39cd8940fb_story.html">six months</a> after the first cases. A WHO spokesperson pushed back against this. “From January 2020, WHO said transmission was occurring between people when they breathe, talk (later sing) and especially in settings like hospitals, households and long term living facilities,” a spokesperson told Vox by email. While some of this confusion stemmed from longstanding <a href="https://www.statnews.com/2024/04/18/covid-airborne-transmission-disease-who-expanded-definition/">disagreement</a> on what exactly constitutes airborne spread, as late as March 2020 the WHO was still confidently <a href="https://x.com/who/status/1243972193169616898?lang=en-GB">tweeting</a>, “FACT: #COVID19 is NOT airborne,” even as people were being infected through the air.&nbsp;</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2025/02/gettyimages-1206560564.jpg?quality=90&#038;strip=all&#038;crop=0,0.0062492188476426,100,99.987501562305" alt="WHO Director-General Tedros Adhanom Ghebreyesus" title="WHO Director-General Tedros Adhanom Ghebreyesus" data-has-syndication-rights="1" data-caption="WHO Director-General Tedros Adhanom Ghebreyesus at a daily press briefing on Covid-19 on March 11, 2020. | Fabrice Coffrini/AFP via Getty Images" data-portal-copyright="Fabrice Coffrini/AFP via Getty Images" />
<p class="has-text-align-none">Trump has also repeatedly <a href="https://www.bbc.com/news/world-us-canada-52496098">criticized</a> the WHO for not fully investigating the <a href="https://www.vox.com/health/23617450/covid-origins-lab-leak-theory-energy-department-sars-china">theory</a> that the Covid-19 virus originated from virological work in a laboratory in Wuhan, rather than the conventional explanation that it began in wild animals sold at a meat market. The WHO sent a team of investigators to China in 2021, but Chinese scientists refused to discuss the so-called “lab leak” theory and then pressured investigators to dismiss the possibility altogether, <a href="https://www.bmj.com/content/374/bmj.n2023">according to</a> the lead scientist on the team.&nbsp;</p>

<p class="has-text-align-none">Again, though, the WHO has no authority to compel member states to turn over data or to cooperate on investigations. In fact, the WHO cannot even work inside a member state without that country’s permission. This is certainly a limitation of the WHO, but that’s because it answers to its member states — it is not some sort of supra-national health policy enforcement body.&nbsp;</p>

<p class="has-text-align-none">Beyond Covid, Trump has also <a href="https://www.reuters.com/world/us/trump-signs-executive-withdrawing-world-health-organization-2025-01-21/">griped</a> that the WHO requires the US to make “unfairly onerous” payments, because US dues exceed the payment the organization demands of China, which has about <a href="https://data.worldbank.org/indicator/SP.POP.TOTL">four times</a> the number of people as in the US.&nbsp;</p>

<p class="has-text-align-none">The WHO is <a href="https://www.who.int/about/funding">funded</a> in two ways. The first is through <a href="https://www.who.int/about/funding/assessed-contributions">assessed contributions</a>, essentially membership dues, that each WHO member state is required to pay each year. The United Nations has a process for <a href="https://www.un.org/en/ga/contributions/Briefing%20on%20scale%20methodology%20June%202024.pdf">determining</a> how much each country owes, but it’s essentially based on a country’s gross domestic product (GDP), not its population size.&nbsp;</p>

<p class="has-text-align-none">US GDP in 2023 was about <a href="https://data.worldbank.org/indicator/NY.GDP.MKTP.CD">1.5 times</a> higher than China’s. That year, the US was required to pay the WHO $<a href="https://open.who.int/2022-23/contributors/contributor?name=United%20States%20of%20America">218 million</a>, about two times more than China was assessed. So while the US does pay more than China, that difference is almost, though not quite, proportional to GDP.</p>

<p class="has-text-align-none">Assessed contributions, however, make up less than <a href="https://www.who.int/about/funding">20 percent</a> of the WHO’s total funds. Its other funding comes from voluntary contributions from member states and non-governmental donors, such as <a href="https://www.euronews.com/health/2023/02/03/how-is-the-world-health-organization-funded-and-why-does-it-rely-so-much-on-bill-gates">the Bill and Melinda Gates Foundation</a>.&nbsp;</p>

<p class="has-text-align-none">Here is where the US and China make vastly different contributions to the WHO. In 2023, China gave the organization about $<a href="https://open.who.int/2022-23/contributors/contributor?name=China">40 million</a> in voluntary contributions plus an additional $935,000 toward an emergency fund on top of its assessed contribution, while the US government donated more than $<a href="https://open.who.int/2022-23/contributors/contributor?name=United%20States%20of%20America">1 billion</a> in voluntary funds and about $47 million toward the emergency fund. In all, that meant the US gave the WHO about $1.27 billion in 2023, about 18 percent of their total budget, while China gave about $156 million when you tally up all contributions. So while the US does give vastly more to the WHO than China, most of that is in voluntary donations.&nbsp;</p>

<p class="has-text-align-none">Of course, the US doesn’t have to pull out of the WHO altogether to rectify this situation — it could simply choose to donate less to the WHO, or mandate that its contributions come with reform. And the institution does need reform.</p>

<h2 class="wp-block-heading has-text-align-none"><strong>Who’s at fault at WHO, explained&nbsp;</strong></h2>

<p class="has-text-align-none">Covid wasn’t the first time the WHO came under international fire. Take the <a href="https://www.vox.com/2014/7/29/5948415/ebola-outbreak-disease-virus-symptoms-africa-facts-guinea-nigeria">2014 Ebola outbreak in West Africa</a>.</p>

<p class="has-text-align-none">The organization was criticized back in 2014 for its long delay in declaring the <a href="https://www.who.int/emergencies/situations/ebola-outbreak-2014-2016-West-Africa">outbreak</a> a public health emergency, which <a href="https://www.bbc.com/news/health-34877787#:~:text=WHO%27s%20director%2Dgeneral%20Margaret%20Chan,not%20calling%20for%20international%20help.">hindered</a> swift containment measures that could have prevented the virus from <a href="https://www.who.int/news-room/spotlight/one-year-into-the-ebola-epidemic/factors-that-contributed-to-undetected-spread-of-the-ebola-virus-and-impeded-rapid-containment#:~:text=The%20Ebola%20outbreak%20demonstrated%20the,as%20well%20as%20logistical%20challenges.">spreading</a> across borders. From the start, the WHO fundamentally <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC7122988/#:~:text=In%20the%20following%20section%2C%20this%20chapter%20surveys,contributed%20to%20the%20spread%20of%20the%20virus.&amp;text=It%20was%20at%20this%20juncture%20the%20flaws,to%20managing%20the%20crisis%20became%20particularly%20apparent.">underestimated</a> the severity of the outbreak — Ebola would go on to kill more than 11,000 people primarily in Guinea, Liberia, and Sierra Leone, with scattered cases reported in the US and several European countries, too. It ultimately took the WHO and its partners two years to get the Ebola outbreak under control.&nbsp;</p>

<p class="has-text-align-none">Despite the number of deaths, Ebola’s spread was limited largely because it isn’t a respiratory disease like Covid-19; rather it <a href="https://www.princegeorgescountymd.gov/departments-offices/health/environmental-health/disease-control/ebola/how-ebola-spreads-person-person#:~:text=It%20can%20be%20spread%20through,the%20virus%20to%20another%20person.">spreads through direct contact</a> with an infected person&#8217;s bodily fluids. But that fact makes the failure to contain Ebola all the more glaring.&nbsp;&nbsp;</p>

<p class="has-text-align-none">To be fair, all outbreak and pandemic responses are chaotic, especially when an entirely novel virus like Covid starts spreading. New information is constantly emerging, and a lot of different individuals and institutions have to come together to coordinate the flow of information and the rollout of interventions or recommendations, even as the full picture of the outbreak is inevitably unclear. Outbreaks often happen in far-flung areas that lack health care workers, hospitals, laboratories, and even roads and internet. <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC8085623/">Cultural practices</a>, economic conditions, and a preexisting lack of trust in politicians and health officials further complicate responses.&nbsp;</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/chorus/uploads/chorus_asset/file/13591525/GettyImages_1060577424.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="A health worker waits to handle a new unconfirmed Ebola patient " title="A health worker waits to handle a new unconfirmed Ebola patient " data-has-syndication-rights="1" data-caption="A health worker waits to handle a new unconfirmed Ebola patient at a newly built Doctors Without Borders-supported Ebola treatment center on November 7, 2018, in the Democratic Republic of the Congo. | John Wessels/AFP/Getty Images" data-portal-copyright="John Wessels/AFP/Getty Images" />
<p class="has-text-align-none">The WHO also came under fire for delaying the dissemination of vaccines to help curb an ongoing <a href="https://www.vox.com/future-perfect/366903/mpox-monkeypox-africa-continental-emergency-drc-who-clade">mpox outbreak</a> which began in May 2022 and spread to more than <a href="https://www.cdc.gov/mpox/situation-summary/index.html">120 countries</a> before the virus became largely confined to central and eastern Africa.&nbsp;</p>

<p class="has-text-align-none">In mid-2022, the <a href="https://www.fda.gov/vaccines-blood-biologics/vaccines/key-facts-about-vaccines-prevent-mpox-disease#:~:text=There%20are%20two%20FDA%2Dapproved,the%20prevention%20of%20mpox%20disease.">US</a> and <a href="https://www.ema.europa.eu/en/human-regulatory-overview/public-health-threats/mpox#:~:text=Tecovirimat-,Vaccine,and%20adolescents%20since%20September%202024.">EU</a> approved an mpox vaccine made by the Danish pharmaceutical company Bavarian Nordic. But the WHO, which has its <a href="https://www.who.int/news-room/fact-sheets/detail/prequalification-of-medicines-by-who#:~:text=WHO%20prequalification%20of%20medicines%20is,treating%20HIV%2C%20tuberculosis%20and%20malaria.">own process</a> for reviewing and approving drugs and vaccines, did not approve the vaccine until <a href="https://www.who.int/news/item/13-09-2024-who-prequalifies-the-first-vaccine-against-mpox#:~:text=The%20WHO%20Strategic%20Advisory%20Group,at%20high%20risk%20of%20exposure.">September 2024</a>.</p>

<p class="has-text-align-none">That delay mattered. For one, other organizations like <a href="https://www.unicef.org/">UNICEF</a> and Gavi that play a critical role in procuring and distributing vaccines in developing countries <a href="https://www.nytimes.com/2024/08/23/health/mpox-vaccines-who-africa.html?searchResultPosition=3">require</a> WHO approval before they can move forward with vaccination campaigns. Many developing countries do not have or have only pared-down versions of drug regulatory agencies so they also rely on the WHO to approve medicines before they roll them out in their countries, explained Rogério Gaspar, the director of WHO’s Department of Regulation and Prequalification. And so when it came to the mpox vaccine, many countries — especially in Africa, where the outbreak was most severe — were waiting for the green light from WHO before they could roll out the needed vaccines, even though the US and Europe had already approved them.</p>

<p class="has-text-align-none">The WHO blames the long delay on Bavarian Nordic. The WHO claimed that the company did not submit the mpox vaccine for review until August 2024, some two years after the mpox outbreak had begun, and that once it did, the WHO approved it within two weeks, according to a WHO spokesperson.&nbsp;</p>

<p class="has-text-align-none">But Bavarian Nordic refutes this timeline. A spokesperson told Vox that the pharmaceutical company first met with WHO in August 2022 and submitted a dossier on the vaccine in May 2023. The dossier they submitted to the WHO contained the same information that led to the European Medicines Agency, the equivalent of the FDA, approving the vaccine for use in Europe. It isn’t clear why the WHO didn’t act sooner. Back in August 2024, the WHO director of health product policy and standards, Deusdedit Mubangizi, told <a href="https://www.nytimes.com/2024/08/23/health/mpox-vaccines-who-africa.html?searchResultPosition=3">reporters</a> that there wasn’t enough data to support its approval. But now, it seems, the WHO has changed its story, ducking accountability once again.&nbsp;</p>

<p class="has-text-align-none">The entire process has frustrated some public health experts. “It&#8217;s almost like WHO saying, hey, we&#8217;re not responsible for our own process,” Jha said. “This is the lack of accountability. It&#8217;s everybody else&#8217;s fault.”</p>

<p class="has-text-align-none">(A WHO spokesperson pointed out that member states did not have to wait until the WHO’s review was complete to buy and distribute the vaccines.)</p>

<p class="has-text-align-none">Over the years, the WHO has tried to address its critics through a laundry <a href="https://www.who.int/about/transformation">list</a> of reform <a href="https://www.who.int/news-room/feature-stories/detail/Donors-making-a-difference--Transforming-WHO">efforts — and there has been some improvement.</a> Between 2020 and 2022, smaller Ebola outbreaks in the Democratic Republic of the Congo, Uganda, and Guinea have been contained in just a few months. That’s a hopeful signal the organization has potentially improved not only its own <a href="https://www.cdc.gov/ebola/outbreaks/index.html">ability to quickly respond to outbreaks</a>, but has also helped build member states’ capacity to detect and contain health emergencies. It also helps that since 2014, scientists have also developed a number of <a href="https://www.who.int/news-room/questions-and-answers/item/ebola-vaccines">vaccines</a> and <a href="https://www.hopkinsmedicine.org/health/conditions-and-diseases/ebola#:~:text=Medications.,including%20the%20Ebola%20Sudan%20strain.">treatments</a> that would certainly help quell an outbreak.</p>

<p class="has-text-align-none">Still, while there were improvements in the Ebola response that can be attributable to the WHO, the organization’s dismal performance during the Covid-19 pandemic suggests that these reforms remain insufficient. And the bigger issue is that the WHO simply cannot admit its mistakes. The organization has still not come out and listed the errors it made during the Covid-19 pandemic. Though the WHO convened an independent panel of experts to review the international response to Covid-19, the panel’s reports largely focus on the failures of WHO member states and say little about the WHO’s own shortcomings.</p>

<p class="has-text-align-none">“There is very little interest at WHO in introspection,” Jha said. “There&#8217;s very little interest in WHO in figuring out how to do better.”&nbsp;</p>

<p class="has-text-align-none">And given how enormous — and how difficult — the WHO’s responsibilities are, that introspection is needed.</p>

<h2 class="wp-block-heading has-text-align-none"><strong>The WHO’s impossible task</strong></h2>

<p class="has-text-align-none">The WHO&#8217;s mission is to foster global public health, but what that means in practice depends on what counts as global. As it stands, its 194 member states (193 without the US) have tasked the organization with outbreak prevention and response and other <a href="https://apps.who.int/gb/bd/pdf_files/BD_49th-en.pdf">responsibilities</a> that impact nearly all countries. That includes setting international health standards and collecting data on an ever-increasing list of health priorities ranging from <a href="https://www.who.int/health-topics/maternal-health">maternal</a> and <a href="https://www.who.int/health-topics/child-health">child health</a> and <a href="https://www.who.int/health-topics/nutrition">nutrition</a> to <a href="https://www.who.int/health-topics/water-sanitation-and-hygiene-wash">sanitation and clean water</a>. But some of the WHO’s work focuses on supplementing national health programs and filling gaps that benefit individual nations — specifically those with the least resources — rather than the world as a whole.</p>

<p class="has-text-align-none">Those responsibilities fit poorly with a Trump administration that is bringing an America First approach to health — and other countries are taking notice. Argentina has <a href="https://www.reuters.com/world/americas/argentina-withdraw-world-health-organization-after-trump-exit-2025-02-05/">announced</a> that it also plans to withdraw from the WHO, while Italian politicians have introduced <a href="https://www.politico.eu/article/italys-far-right-league-party-backs-trumps-pullout-from-who/">legislation</a> that would do the same. Other European countries have <a href="https://www.theguardian.com/global-development/2025/jan/06/uk-cuts-health-aid-vulnerable-countries-recruiting-nurses-analysis-royal-college-nursing-research#:~:text=Between%202020%20and%202023%2C%20direct,%C2%A324m%20to%20%C2%A34m.">slashed</a> global health aid budgets in recent years.&nbsp;</p>

<p class="has-text-align-none">That the US cannot remain a WHO member while also consciously putting itself first highlights a friction in the field. Is global health about containing dangerous outbreaks so they don’t breach your own border and pose a threat to national security? Or is global health about saving lives and improving the health of everyone, regardless of their nationality? Can competing nation-states like China and the US set aside their political warfare and come together on one issue — health — or has the time for international cooperation finally ended?</p>

<p class="has-text-align-none">One way to <a href="https://gh.bmj.com/content/1/2/e000047">address</a> that contradiction would be for the WHO to <a href="https://gh.bmj.com/content/1/2/e000047">scale back</a> on the number of health areas it is involved in and focus primarily on issues that actually transcend borders. This would include infectious diseases — but only those that present a truly global threat.&nbsp;</p>

<p class="has-text-align-none">The WHO itself puts together a <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC11627490/">list of pathogens</a> with the potential to cause a pandemic. It includes familiar diseases such as West Nile, Zika, Ebola, and Covid-19. Many of these have already caused deadly outbreaks and pandemics. Something else that transcends borders: products such as cigarettes or baby formula. The WHO might also have a role to play in regulating the safety of these products, according to <a href="https://hsph.harvard.edu/profile/jesse-b-bump/">Jesse Bump</a>, a public health professor at the Harvard T.H. Chan School of Public Health.</p>

<p class="has-text-align-none">This recommendation is not to say that newborn and maternal health or access to clean water are not important, life-saving services that everyone on Earth should have. But these represent more national health priorities for the countries dealing with these issues and not truly global threats.&nbsp;</p>

<p class="has-text-align-none">Without some form of additional support, paring down the WHO’s focus areas would have fatal consequences for some places. Particularly in low-income countries, the WHO serves as a lifeline of essential health services and often fills many of the responsibilities that national health agencies in wealthy nations like the US handle, a WHO spokesperson explained.</p>

<p class="has-text-align-none">Of course, the fact that the WHO is tasked with addressing so many different areas of health fundamentally reflects both the massive health disparities around the world and the way the organization is funded. Consider the health challenges that a country like the US faces compared to many developing countries. In places like Niger, Papua New Guinea, Chad, and the DRC, <a href="https://www.worldvision.org/clean-water-news-stories/10-worst-countries-access-clean-water">more than half</a> of the population does not have access to clean drinking water or basic water services. More than <a href="https://worldpopulationreview.com/country-rankings/malnutrition-rate-by-country">50 percent</a> of people in Somalia and Haiti are malnourished. In southern Africa, <a href="https://ourworldindata.org/data-insights/whats-the-leading-cause-of-death-in-each-country">HIV</a> is still a leading cause of death; in parts of West Africa, malaria is a leading cause of death.&nbsp;</p>

<p class="has-text-align-none">In much of the global north, by contrast, these health challenges are virtually nonexistent, and where they are present, it’s because of national priorities, not a lack of national resources.&nbsp;</p>

<p class="has-text-align-none">Consider as well the drastic difference in the health workforce around the world. In many low- and middle-income counties, there are major shortages of doctors and nurses, not to mention specialists such as neurologists or surgeons. In more than 50 countries, mostly in Africa and the Middle East, there are fewer than <a href="https://data.worldbank.org/indicator/SH.MED.PHYS.ZS?most_recent_value_desc=true">one doctor</a> per 1,000 people in the entire country. The US has almost four times as many doctors per capita.</p>

<p class="has-text-align-none">What this means is that the state of health and health care is so grossly unequal across countries that one organization cannot possibly address them all while also ensuring that every member states benefits equally from their WHO membership.&nbsp;</p>

<p class="has-text-align-none">And the benefits are unequal, at least in strict financial terms. Last year, countries in Africa and the WHO’s Eastern Mediterranean region — which includes parts of North Africa and the Middle East including some very poor and conflict-afflicted member states such as Afghanistan, Yemen, Syria, Somalia, and Sudan — received <a href="https://cdn.who.int/media/docs/default-source/pb-website/a76_4-en.pdf?sfvrsn=648fd79f_7">$2.9 billion</a>, almost half of the WHO’s $6.8 billion budget. The region of the Americas, which includes the US, received the least amount of funding, just over $300 million. But even here, it’s important to understand that the inequality in who gives and who gets from the WHO is largely a function of the fact that some regions and countries simply have a massively greater need for international aid.&nbsp;</p>

<p class="has-text-align-none">It’s important to remember that the WHO has limited control over its own agenda. It is member states themselves who <a href="https://www.who.int/about/accountability/budget#:~:text=The%20biennial%20Programme%20budgets%20themselves,the%20strategic%20direction%20of%20WHO.">vote</a> on the organization’s scope of work and approve its budget. Beyond the required payments, countries and other donors can earmark their voluntary funds for specific causes. The US, for instance, earmarks <a href="https://open.who.int/2024-25/contributors/contributor?name=United%20States%20of%20America">more than half</a> of its funds for epidemic prevention or response and polio eradication while Nordic countries typically focus their funding on maternal health.&nbsp;</p>

<p class="has-text-align-none">This approach to funding helps the WHO account for individual member state priorities but also allows countries to use funds to influence the WHO’s scope of work. Ultimately, it means that the WHO has little choice but to expand and scatter its workforce to make sure every country’s pet projects get completed.&nbsp;</p>

<h2 class="wp-block-heading">Is there any room for WHO in America First?</h2>

<p class="has-text-align-none">Short of remaking the WHO into an institution under the leadership of the US government, it’s difficult to imagine that any amount of reform will satisfy the current administration. The organization&#8217;s mission is completely misaligned with Trump’s “America First” agenda. In the WHO, as in most other UN international bodies, America does not come first. It has the same vote as every other member state, even though the US contributes more money than any other country. </p>

<p class="has-text-align-none">But despite its many shortcomings, the US needs the WHO. Only an international health agency such as the WHO can overcome the nuanced complexities of economic competition, geopolitics, and even outright war, to respond to global health emergencies. The WHO serves as a bridge for sharing information and even biological samples of pathogens, which is critical for understanding how a disease will spread and for developing medicines and vaccines.</p>

<p class="has-text-align-none">Trump’s vision of global health or public health, for that matter, is unclear. Just as unclear is whether Trump’s executive order on the WHO is even <a href="https://healthpolicy-watch.news/trump-may-face-lawsuit-over-his-withdrawal-of-us-from-who/">legal</a>. Members of Congress have <a href="https://cohen.house.gov/media-center/press-releases/congressman-cohen-leads-letter-opposing-us-withdrawal-world-health">asked</a> Trump to reconsider. Though the full impact of the US withdrawal will probably not be felt for about a year, the WHO’s director-general has already <a href="https://healthpolicy-watch.news/who-freezes-recruitment-and-slashes-travel-to-mitigate-us-withdrawal/">ordered</a> a hiring freeze, mandated that some contracts be renegotiated, and directed staff in country offices to provide only essential support.  </p>

<p class="has-text-align-none">As the WHO adapts to a future without US investment, the Trump administration is also gutting other key global health efforts. This month, thousands of USAID staff were laid off, leaving only about <a href="https://www.reuters.com/world/us/trump-administration-keeping-only-294-usaid-staff-out-over-10000-globally-2025-02-06/">300 employees</a> of a once 10,000-person workforce. It isn’t yet clear what global health areas the drastically smaller agency will work on — or whether it will <a href="https://www.justsecurity.org/107267/can-president-dissolve-usaid-by-executive-order/">exist at all</a> — and it wouldn’t be surprising if the administration <a href="https://www.nbcnews.com/health/health-news/trump-dei-hiv-cdc-website-removed-lgbtq-rcna190068">goes after</a> other global health initiatives like the ones led by the Centers for Disease Control and Prevention.&nbsp;</p>

<p class="has-text-align-none">American retreat from both the WHO and its own broader global health efforts paradoxically makes the case for WHO reform all the more important. Many complaints about how the WHO does its work are valid, especially given its reluctance to confront mistakes. But much of what it is criticized for is built into the way the institution itself operates or reflects a world with hugely varying health problems and national abilities to meet them. Still, the WHO must do better because it is the only organization uniquely placed to bridge diplomatic tensions and address international health threats. The most hopeful read on Trump’s action will shock the bureaucracy into action, and lead the Trump administration to ultimately realize that an American-first approach must include the WHO.&nbsp;</p>

<p class="has-text-align-none"></p>
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									</content>
			
					</entry>
			<entry>
			
			<author>
				<name>Jessica Craig</name>
			</author>
			
			<title type="html"><![CDATA[Eggs are pricey again. What&#8217;s the government doing about it?]]></title>
			<link rel="alternate" type="text/html" href="https://www.vox.com/future-perfect/394511/bird-flu-eggs-human-death-prices-government-response" />
			<id>https://www.vox.com/?p=394511</id>
			<updated>2025-01-24T11:31:09-05:00</updated>
			<published>2025-01-26T06:00:00-05:00</published>
			<category scheme="https://www.vox.com" term="Animal Welfare" /><category scheme="https://www.vox.com" term="Bird Flu" /><category scheme="https://www.vox.com" term="Future Perfect" /><category scheme="https://www.vox.com" term="Health" /><category scheme="https://www.vox.com" term="Infectious Disease" /><category scheme="https://www.vox.com" term="Public Health" /><category scheme="https://www.vox.com" term="Vaccines" />
							<summary type="html"><![CDATA[Bird flu is surging in the US again and has, once again, sent egg prices skyrocketing. Nearly 13 million birds have been infected or culled in the past month alone, contributing to shortages. A carton of eggs today costs more than $4 on average, up from about $2.50 a year ago.&#160; Prices aren&#8217;t the only [&#8230;]]]></summary>
			
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<figure>

<img alt="An egg shortage sign hanging in front of a grocery story refrigerator with eggs" data-caption="Egg shortage signage is displayed on partially empty shelves at a Sprouts Farmer’s Market grocery store in Lawndale, California, on January 2, 2025. | Patrick T. Fallon/AFP via Getty Images" data-portal-copyright="Patrick T. Fallon/AFP via Getty Images" data-has-syndication-rights="1" src="https://platform.vox.com/wp-content/uploads/sites/2/2025/01/gettyimages-2191628137.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
	<figcaption>
	Egg shortage signage is displayed on partially empty shelves at a Sprouts Farmer’s Market grocery store in Lawndale, California, on January 2, 2025. | Patrick T. Fallon/AFP via Getty Images	</figcaption>
</figure>
<p class="has-text-align-none">Bird flu is <a href="https://www.cidrap.umn.edu/avian-influenza-bird-flu/avian-flu-surge-continues-us-poultry-farms-feds-address-contamination-raw">surging</a> in the US again and has, once again, sent egg prices <a href="https://www.axios.com/2025/01/21/bird-flu-egg-prices-avian-influenza-trump">skyrocketing</a>. Nearly <a href="https://www.aphis.usda.gov/livestock-poultry-disease/avian/avian-influenza/hpai-detections/commercial-backyard-flocks">13 million</a> birds have been infected or culled in the past month alone, contributing to shortages. A carton of eggs today <a href="https://fred.stlouisfed.org/series/APU0000708111">costs more than $4 on average</a>, up from about $2.50 a year ago.&nbsp;</p>

<p class="has-text-align-none">Prices aren&#8217;t the only thing making headlines — the virus has recently taken a human life, too. After nearly three years of <a href="https://www.vox.com/science/23793697/bird-flu-avian-influenza-explained-pandemic-potential-wildlife">warnings</a> from leading public health and <a href="https://www.vox.com/future-perfect/24155545/bird-flu-vaccines-h5n1-avian-flu-cows">animal agriculture</a> experts that bird flu was becoming a threat to human beings, Louisiana health officials <a href="https://ldh.la.gov/news/H5N1-death">reported</a> earlier this month that an individual died from the virus, the first reported human death in the US from bird flu.&nbsp;</p>

<p class="has-text-align-none">This particular strain of bird flu, H5N1, has been circulating in the US and infecting poultry since <a href="https://www.aphis.usda.gov/news/program-updates/hpai-indiana">February 2022</a>. So far, <a href="https://www.aphis.usda.gov/livestock-poultry-disease/avian/avian-influenza/hpai-detections/commercial-backyard-flocks">millions of birds</a> have been infected or were culled to prevent further spread. But, as <a href="https://www.vox.com/even-better/24145304/bird-flu-h5n1-avian-influenza-pandemic">Vox reported previously</a>, the concern has always been that this strain could jump from birds, then to another animal, and then to humans, and evolve along the way into something much deadlier to humans.&nbsp;</p>

<p class="has-text-align-none">Last March, the virus made its way to US <a href="https://www.vox.com/future-perfect/24128700/bird-fludairy-meat-industry-h5n1-cows-milk-eggs-safety">dairy cows</a>. About a <a href="https://www.cdc.gov/bird-flu/avian-timeline/2020s.html#:~:text=In%20April%202022%2C%20the%20first,virus%20rather%20than%20actual%20infection.">month</a> later, Americans began getting infected in greater numbers — the majority of those infected, health officials say, were exposed to commercial cattle or poultry farms. Today, nearly 1,000 cattle herds across <a href="https://www.aphis.usda.gov/livestock-poultry-disease/avian/avian-influenza/hpai-detections/hpai-confirmed-cases-livestock">16 states</a> have been affected, according to the US Department of Agriculture (USDA).</p>

<p class="has-text-align-none">The deceased Louisiana patient, however, was <a href="https://ldh.la.gov/news/H5N1-death">infected</a> by backyard poultry wild birds. The individual was older than 65 years old and had underlying medical conditions, which likely increased their <a href="https://www.cdc.gov/flu/prevention/index.html#:~:text=People%20at%20higher%20risk%20of%20serious%20flu%20complications%20include%20young,people%2065%20years%20and%20older.">risk</a> for severe disease and death, as it does for conventional flu.</p>

<p class="has-text-align-none">This case brings the total number of documented human infections in the US to <a href="https://www.cdc.gov/bird-flu/situation-summary/index.html">67</a>. Human infections have been reported in 10 states so far, but most cases have occurred in California, where the governor declared a <a href="https://www.cdph.ca.gov/Programs/CID/DCDC/Pages/Bird-Flu.aspx#:~:text=On%20December%2018%2C%202024%2C%20Governor,with%20poultry%20and%20dairy%20cows.">state of emergency</a> in December.&nbsp;</p>

<p class="has-text-align-none">As much as the death set off alarm bells, the risk to most people in the US from bird flu remains very low. Humans aren’t catching bird flu from one another right now. That could always change, though. The H5N1 virus could mutate in some way that makes it easily transmissible between humans. This is how a flu pandemic would begin.</p>

<p class="has-text-align-none">And as long as that possibility remains, it’s easy to feel as though not enough is being done to prevent the possibility of another terrible pandemic, especially when influencers are touting raw milk as a potential, natural “medicine” for various ailments (it’s not) or when official government responses feel unclear or <a href="https://www.vanityfair.com/news/story/inside-the-bungled-bird-flu-response">insufficient</a>. (There is some truth to that.)</p>

<p class="has-text-align-none">From egg prices and vaccines to pandemic potential and disease monitoring, here are five answers about the ongoing response to bird flu.</p>

<h2 class="wp-block-heading has-text-align-none"><strong>How is the government responding to bird flu — and is it doing enough?&nbsp;</strong></h2>

<p class="has-text-align-none">Bird flu mostly spreads among wild and domestic birds, but the virus sometimes does <a href="https://www.cdc.gov/bird-flu/virus-transmission/avian-in-other-animals.html#:~:text=Bird%20flu%20viruses%20have%20in,such%20as%20tigers%20and%20leopards.">spill over</a> and infect other animals. In the past three years, bird flu has infected cows, seals, bears, dogs, cats, and a number of other mammals.</p>

<p class="has-text-align-none">As with any major disease, the Centers for Disease Control and Prevention (CDC) are working alongside state agencies to track cases in humans. But because most people eat animals for food, there are two other key players involved: the USDA and the Food and Drug Administration (FDA). </p>

<p class="has-text-align-none">The USDA leads federal efforts to monitor and contain bird flu among farm animals, live bird markets, backyard flocks, and wild animals. The agency <a href="https://www.aphis.usda.gov/livestock-poultry-disease/avian/avian-influenza#:~:text=Surveillance%20in%20Domestic%20Poultry,production%20flocks%2C%20and%20backyard%20flocks.&amp;text=Because%20wild%20birds%20can%20carry,in%20the%20wild%20bird%20population.">develops</a> biosafety and biosecurity standards to prevent the spread of bird flu, and then assists state agencies and commercial farmers to implement those measures. In addition, the agency runs a bird flu surveillance program that <a href="https://www.aphis.usda.gov/national-wildlife-programs/nwdp/avian-health#:~:text=NWDP%20collects%20samples%20from%20wild,and%20a%20variety%20of%20arboviruses.">involves</a> trapping wild birds, collecting samples from them, and testing them for H5N1 and other pathogens. Wild birds are a reservoir for bird flu, meaning that the virus is normally spread among them and from there spills over to infect domestic birds and other mammals.&nbsp;&nbsp;</p>

<p class="has-text-align-none">Farmers and poultry or cow owners who suspect their flock or herd is infected with bird flu can report the cases to the USDA and to state animal health officials or to their veterinarian, who can then report the cases up the chain. The USDA has a network of laboratories that tests samples from flocks and herds across the country for H5N1 and other pathogens.&nbsp;</p>

<p class="has-text-align-none">But while this might seem like the USDA has broad reach to closely monitor poultry and cattle across the country, it is, in reality, a deeply faulty system. A lot of farmers don’t report illnesses to their veterinarian or state health officials, <a href="https://www.reuters.com/business/healthcare-pharmaceuticals/us-undercounts-bird-flu-cattle-farmers-shun-testing-2024-08-15/#:~:text=Some%20farmers%20do%20not%20test,dairy%20farmer%20in%20eastern%20Kansas.">citing</a> distrust in the government or because they think the epidemic is a hoax. Other farmers <a href="https://www.statnews.com/2024/07/03/bird-flu-outbreak-turns-dairy-veterinarians-into-avian-flu-deputies/">do not allow</a> veterinarians to test their flocks or herds for the virus.&nbsp;&nbsp;</p>

<p class="has-text-align-none">If bird flu is detected on a farm or in a live bird market, the USDA mobilizes funding and personnel to those areas to cull — in particularly <a href="https://www.vox.com/future-perfect/23053296/bird-flu-chickens-turkeys-cull-depopulation-ventilation-shutdown">gruesome ways</a>, such as spraying birds with a water-based foam to suffocate them or closing barn vents and causing birds to die of heat stroke — and dispose of infected animals to prevent further spread.&nbsp; Cows are spared this horrific end because they don’t get so severely sick from bird flu and are too expensive to kill en masse.&nbsp;</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2025/01/gettyimages-2149177620.jpg?quality=90&#038;strip=all&#038;crop=0,0.0057730054266258,100,99.988453989147" alt="Signage for the Department of Agriculture seen outside the Jamie L Whitten Federal Building" title="Signage for the Department of Agriculture seen outside the Jamie L Whitten Federal Building" data-has-syndication-rights="1" data-caption="" data-portal-copyright="J. David Ake/Getty Images" />
<p class="has-text-align-none">While the USDA works closely with the agricultural sector, the FDA is more consumer-facing, ensuring food products are safe. The FDA <a href="https://www.fda.gov/food/egg-guidance-regulation-and-other-information/questions-and-answers-regarding-safety-eggs-during-highly-pathogenic-avian-influenza-outbreaks">monitors</a> egg-laying chickens and those slaughtered for meat for signs of infection. Commercial eggs are tested for H5N1 before they are transported to grocery stores and animals are <a href="https://www.nationalchickencouncil.org/bird-flu-its-not-in-your-food/questions-and-answers-on-avian-influenza/">inspected</a> before and after slaughter for any signs of disease. (We’ll get to how effective this process is in the next section.)</p>

<p class="has-text-align-none">Since the beginning of the outbreak, the FDA has also led a number of studies to test dairy products for H5N1 and to determine how to make contaminated dairy products safe for consumption. The administration also <a href="https://www.fda.gov/food/alerts-advisories-safety-information/investigation-avian-influenza-h5n1-virus-dairy-cattle#:~:text=The%20FDA%20is%20providing%20an,to%20human%20and%20animal%20health.">funds</a> academic researchers to test methods for killing the virus in dairy products and even to experiment with gene-edited chickens that are immune to H5N1.&nbsp;</p>

<p class="has-text-align-none">The CDC, meanwhile, monitors H5N1 infections among humans, tracks people who were exposed to infected animals, and investigates each reported case to determine how the person was infected and if any close contacts of the infected person may also be at risk of contracting bird flu.&nbsp;</p>

<p class="has-text-align-none">State health departments are required to report cases to the CDC; doctors and physicians are, in turn, mandated to report H5N1 cases to state health departments. The CDC also gathers and analyzes data from emergency departments around the US to understand if there might be an uptick in H5N1 cases. But, as we have seen with <a href="https://www.vox.com/future-perfect/2022/8/14/23302054/monkeypox-data-health-care-covid-collection">Covid and Mpox</a>, this system does not always function perfectly, or at times even well, because of reporting lags and a lack of infrastructure or human resources. The CDC also runs a wastewater surveillance system and regularly tests wastewater samples from hundreds of collection sites for H5N1.&nbsp;</p>

<p class="has-text-align-none">Although the FDA, USDA, and CDC might seem to have all the legislation, policies, monitoring, and surveillance programs in place, federal government agencies seem to have resigned themselves to largely sitting back and watching this epidemic unfold. Veterinarians and public health experts have <a href="https://www.theatlantic.com/health/archive/2025/01/bird-flu-embarrassing/681264/?gift=1wJJOWpbGcy0FRPza_6RtEDNM3RblYUsa2CG22BM-ck&amp;utm_source=copy-link&amp;utm_medium=social&amp;utm_campaign=share">criticized</a> the USDA for prioritizing industry profits and exports instead of rolling out a vaccination <a href="https://www.vox.com/future-perfect/24155545/bird-flu-vaccines-h5n1-avian-flu-cows">program</a> that may have prevented bird flu from spilling over into cows or humans in the first place. The USDA has also failed to take obvious measures such as shutting down cross-state transportation of cattle, which has led to hundreds of infected herds in multiple states.&nbsp;</p>

<p class="has-text-align-none">Other efforts — such as the USDA’s national milk testing <a href="https://www.aphis.usda.gov/livestock-poultry-disease/avian/avian-influenza/hpai-detections/livestock/nmts">program</a> — have been too little, too late and still do not require mandatory participation from every US state where bird flu has been reported. And while most of the failure to contain bird flu lies with the FDA and USDA, the CDC has not pushed to expedite research and development for a bird flu vaccine in humans, which might be needed if the disease becomes more widespread and more severe in people, especially farm workers in close contact with infected animals. </p>

<p class="has-text-align-none">It’s currently unclear what new policies the Trump administration might usher in to combat bird flu in humans or animals. President Donald Trump has vowed to cut federal funding which may impact how the various federal agencies operate. Concerningly, on Tuesday, the Trump administration ordered staff at agencies including the CDC and FDA to <a href="https://www.cnn.com/2025/01/21/health/hhs-cdc-fda-trump-pause-communication/index.html">pause</a> external communications, including social media and web posts, to the public.&nbsp;</p>

<h2 class="wp-block-heading has-text-align-none"><strong>When will egg prices go down?&nbsp;</strong></h2>

<p class="has-text-align-none">The USDA forecasts that egg prices will continue to rise through the first few months of 2025 before dropping to about half the peak price, according to the agency’s January <a href="https://www.usda.gov/oce/commodity/wasde/wasde0125.pdf">forecasts</a>. However, new or expanding outbreaks in the US could disrupt this.</p>

<h2 class="wp-block-heading has-text-align-none"><strong>Can you contract bird flu from contaminated eggs, milk, and other meat and dairy products?&nbsp;</strong></h2>

<p class="has-text-align-none">In short, it’s very unlikely that the average American will contract bird flu from consuming milk, eggs, cheese, meat, or other animal products. Although the FDA <a href="https://www.fda.gov/food/alerts-advisories-safety-information/investigation-avian-influenza-h5n1-virus-dairy-cattle">found</a> last year that about 20 percent of milk, cheese, and other dairy products contained genetic material from the bird flu virus, researchers at the agency also confirmed that pasteurization — the process of briefly heating milk — kills the virus. Fortunately, <a href="https://www.fda.gov/food/alerts-advisories-safety-information/investigation-avian-influenza-h5n1-virus-dairy-cattle#:~:text=The%20FDA%20is%20providing%20an,to%20human%20and%20animal%20health.">99 percent</a> of the country’s milk supply comes from farms that participate in the agency’s milk safety program which mandates that milk is pasteurized. This means that buying milk or cheese from a grocery store in the US is a safe bet. To be sure, check the label to make sure it contains the word &#8220;pasteurized.&#8221;&nbsp;</p>

<p class="has-text-align-none">What might be riskier is buying milk from noncommercial farms, like a vendor at your local farmers market or your neighbor down the street who sells milk or cheese out of their house. If that vendor or neighbor pasteurizes their milk, then you’re probably good to go. </p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2025/01/gettyimages-2186840161.jpg?quality=90&#038;strip=all&#038;crop=0,0.018594272963931,100,99.962811454072" alt="Bottles of 100% raw milk" title="Bottles of 100% raw milk" data-has-syndication-rights="1" data-caption="" data-portal-copyright="Justin Sullivan/Getty Images" />
<p class="has-text-align-none">There is also a growing trend of consuming <a href="https://www.cdc.gov/food-safety/foods/raw-milk.html">raw milk</a>, or milk that has not been pasteurized. Some social media influencers <a href="https://www.rollingstone.com/culture/culture-features/raw-milk-explained-tiktok-influencers-health-1235042145/">claim</a> that raw milk is healthier than pasteurized milk. A handful of scientific <a href="https://www.sciencedirect.com/science/article/abs/pii/S2213219819309560">studies</a> have even reported a link between consuming “farm” milk, which sometimes includes raw milk, with a lower risk of developing allergies and <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC5581320/">asthma</a>. The FDA has, however, <a href="https://www.fda.gov/food/buy-store-serve-safe-food/raw-milk-misconceptions-and-danger-raw-milk-consumption">debunked</a> many of the health claims associated with raw milk and further warns that drinking raw milk may expose people to H5N1 and a host of other disease-causing pathogens. (Between 1998 and 2018, consuming raw milk caused more than <a href="https://www.fda.gov/food/buy-store-serve-safe-food/dangers-raw-milk-unpasteurized-milk-can-pose-serious-health-risk">2,600</a> illnesses, more than 200 of which required hospitalization.)&nbsp;</p>

<p class="has-text-align-none">So, your best bet is to avoid drinking raw milk and stick to the pasteurized stuff.&nbsp;</p>

<p class="has-text-align-none">Eggs and chicken are also safe to consume. Avian influenza causes such severe disease in chickens and other egg-producing poultry that infected animals are most likely too sick to even produce eggs. But even if sick chickens were producing eggs or were slaughtered for their meat, all commercial poultry flocks in the US are monitored for signs of infection. All eggs are tested for H5N1 before they are transported to grocery stores and animals are inspected before and after slaughter for any signs of disease.</p>

<p class="has-text-align-none">But such inspections aren’t 100 percent foolproof. While the FDA also requires eggs to be <a href="https://www.fda.gov/regulatory-information/search-fda-guidance-documents/small-entity-compliance-guide-prevention-salmonella-enteritidis-shell-eggs-during-production#:~:text=diverting%20to%20treatment?-,Yes.,must%20be%20legible%20and%20conspicuous.">tested</a> for other pathogens such as salmonella before they leave the farm, outbreaks of those diseases still occur from time to time. (A salmonella outbreak in 2024, for instance, spanned <a href="https://www.foodsafetynews.com/2025/01/foodborne-illness-outbreaks-overlap-from-2024-into-2025/#:~:text=Another%20large%20outbreak%20in%202024,caused%20illnesses%20in%20this%20outbreak.">12 states</a> and landed 34 people in the hospital.) This may be, in part, because not every single egg is tested for salmonella. Egg producers are required only to test a representative <a href="https://www.fda.gov/regulatory-information/search-fda-guidance-documents/small-entity-compliance-guide-prevention-salmonella-enteritidis-shell-eggs-during-production#:~:text=diverting%20to%20treatment?-,Yes.,must%20be%20legible%20and%20conspicuous.">sample</a> of eggs from each batch. Eggs can also be contaminated during packing or transportation from the farm to the grocery store.&nbsp;</p>

<p class="has-text-align-none">The good news is that cooking eggs and meat to recommended temperatures and using proper precautions when handling eggs or meat (like washing your hands after handling them) would also kill the bird flu virus.&nbsp;</p>

<h2 class="wp-block-heading has-text-align-none"><strong>What&#8217;s the deal with bird flu vaccines?</strong></h2>

<p class="has-text-align-none">Currently, there are no bird flu vaccines available for humans or poultry or cows. The CDC has developed a few vaccine <a href="https://www.cdc.gov/bird-flu/prevention/index.html#cdc_prevention_myths-vaccination">candidates</a> for humans that the agency says could be used to develop a vaccine. Additional data regarding the vaccine’s effectiveness has not been released. According to the CDC, the annual flu shot offers no <a href="https://www.cdc.gov/bird-flu/prevention/index.html#:~:text=While%20getting%20a%20seasonal%20flu,weeks%20before%20their%20potential%20exposure.">protection</a> against bird flu, but it is unclear if or how the agency actually tested this.&nbsp;</p>

<p class="has-text-align-none">While it is critical for the US government to continue funding vaccine research and development in case a deadlier pandemic emerges, the CDC says there is not an immediate need for widespread vaccination efforts. There have been fewer than <a href="https://www.cdc.gov/bird-flu/situation-summary/index.html">100 documented</a> human infections in the US in the past year. This is likely an undercount given that farm workers are most likely to be infected and may be less likely to seek medical treatment. But more importantly, health officials have documented only three severe bird flu cases, and only one case resulted in death. Globally, there have been nearly <a href="https://www.who.int/docs/default-source/wpro---documents/emergency/surveillance/avian-influenza/ai_20230203.pdf">1,000</a> H5N1 infections among humans between 2003 and 2024, and about half of those people died. </p>

<p class="has-text-align-none">Any threat from the virus now has to be weighed against potential <a href="https://www.cdc.gov/vaccines/basics/possible-side-effects.html">side effects</a> of vaccines, such as Guillain-Barré Syndrome, a condition triggered by an infection that causes the immune system to attack nerves. Given that the current H5N1 strain is causing mostly mild disease, then, at least as of right now, most people would not need to get vaccinated against bird flu even if a vaccine was available.&nbsp;</p>

<p class="has-text-align-none">However, this could change rapidly. Any day, the H5N1 virus might mutate to spread from person to person or to cause more severe illness, in which case vaccination might become an important tool.&nbsp;</p>

<p class="has-text-align-none">Another approach for vaccination might be to only vaccinate farm workers and other populations who are exposed to infected birds or cattle, and therefore at a higher risk of developing bird flu. Last year, Finland <a href="https://www.reuters.com/business/healthcare-pharmaceuticals/finland-start-bird-flu-vaccinations-humans-2024-06-25/">adopted</a> this approach and started offering bird flu vaccines to farm workers.&nbsp;</p>

<p class="has-text-align-none">Perhaps the better question to ask here is why we aren’t vaccinating birds or cows against bird flu. I posed that question to infectious disease experts and an economist at the Food and Agriculture Organization last May. I learned that, in short, vaccinating poultry against bird flu <a href="https://www.vox.com/future-perfect/24155545/bird-flu-vaccines-h5n1-avian-flu-cows">would impact trade</a> and would require US trade agreements with foreign countries to be rewritten. The veterinarians I interviewed were particularly frustrated with this reasoning.</p>

<p class="has-text-align-none">“I’m a poultry veterinarian, and as a veterinarian, I don’t like the idea that you tell me to go fight the biggest fight of my career and you say, here’s your gun; first, let’s unload it. Now, go,” Carol Cardona, a professor at the University of Minnesota’s College of Veterinary Medicine, told me last year.</p>

<p class="has-text-align-none">Last week, the USDA <a href="https://www.reuters.com/business/healthcare-pharmaceuticals/us-build-new-stockpile-bird-flu-vaccine-poultry-2025-01-08/#:~:text=The%20U.S.%20built%20a%20poultry,strains%2C%22%20the%20release%20said.">said</a> it was beginning to stockpile bird flu vaccines for use in poultry but still hasn’t pushed for actual vaccination efforts. The USDA has a history of this. During the 2014–2015 bird flu outbreak, the US government <a href="https://www.aphis.usda.gov/media/document/2086/file">stockpiled</a> almost 5 million doses of a vaccine for poultry but never used them. But because bird flu, like the seasonal flu, is a rapidly mutating virus, those vaccines are now useless.</p>

<h2 class="wp-block-heading has-text-align-none"><strong>Will bird flu cause the next pandemic?</strong>&nbsp;</h2>

<p class="has-text-align-none">In the US, bird flu has been circulating among birds for nearly three years now and has been sporadically spreading from birds to humans for about a year. It hasn’t caused a widespread pandemic among humans yet. That might indicate that the potential for a future pandemic is low, but, in truth, scientists and public health officials really aren’t great at predicting or even understanding why certain viruses suddenly escalate into uncontrollable worldwide outbreaks.&nbsp;</p>

<p class="has-text-align-none">The key ingredient this epidemic needs to become a widespread pandemic among people is human-to-human transmission. So far, there have been no documented instances of this. For this reason, the CDC says that bird flu presents a low risk to the general public. Farm workers, hunters, and other people who come into contact with wild birds, poultry, and cows are at a higher risk of contracting H5N1.&nbsp;</p>

<p class="has-text-align-none">However, while the risk to most people might be low now, the longer the epidemic in poultry continues and the more opportunities the virus has to adapt to spread amongst humans, the more likely the risk for a pandemic becomes.</p>
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			<author>
				<name>Jessica Craig</name>
			</author>
			
			<title type="html"><![CDATA[Have we cured AIDS?]]></title>
			<link rel="alternate" type="text/html" href="https://www.vox.com/explain-it-to-me/396016/hiv-aids-cure-pepfar-who-progress" />
			<id>https://www.vox.com/?p=396016</id>
			<updated>2025-01-21T17:06:49-05:00</updated>
			<published>2025-01-22T08:00:00-05:00</published>
			<category scheme="https://www.vox.com" term="Explain It to Me" /><category scheme="https://www.vox.com" term="Future Perfect" /><category scheme="https://www.vox.com" term="Health" /><category scheme="https://www.vox.com" term="Infectious Disease" /><category scheme="https://www.vox.com" term="Public Health" />
							<summary type="html"><![CDATA[Vox reader Burak Ova asks: What is HIV and what is AIDS? How is it transmitted? What are the prevention methods? Is there a cure? Human immunodeficiency virus (HIV) killed millions of people every year in the early 2000s during the height of the AIDS pandemic. Now, some two decades later, scientific advancements and public [&#8230;]]]></summary>
			
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<img alt="A figure lies on a twin bed with a yellow iron bed frame." data-caption="An AIDS patient lies on her bed at the community hospital in Bangui, Central African Republic, on January 27, 2022. | Barbara Debout/AFP via Getty Images" data-portal-copyright="Barbara Debout/AFP via Getty Images" data-has-syndication-rights="1" src="https://platform.vox.com/wp-content/uploads/sites/2/2025/01/gettyimages-1238336942.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
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	An AIDS patient lies on her bed at the community hospital in Bangui, Central African Republic, on January 27, 2022. | Barbara Debout/AFP via Getty Images	</figcaption>
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<p class="has-text-align-none"><em>Vox reader Burak Ova asks: What is HIV and what is AIDS? How is it transmitted? What are the prevention methods? Is there a cure?</em></p>

<hr class="wp-block-separator has-alpha-channel-opacity" />

<p class="has-text-align-none">Human immunodeficiency virus (<a href="https://www.cdc.gov/hiv/index.html">HIV</a>) killed <a href="https://www.unaids.org/en/resources/fact-sheet#:~:text=AIDS%2Drelated%20deaths%20have%20been,1.7%20million%5D%20people%20in%202010.">millions</a> of people every year in the <a href="https://data.unaids.org/pub/report/2004/2004_epiupdate_en.pdf">early 2000s</a> during the height of the AIDS pandemic. Now, some two decades later, scientific advancements and public health interventions have transformed one of the deadliest diseases into something manageable, where a regular dose of <a href="https://www.cdc.gov/hiv/prevention/prep.html">medication nearly prevents its spread</a> altogether.</p>

<p class="has-text-align-none">So you’re right to wonder whether we’ve squashed AIDS, at least to the point where people don’t have to worry about it.&nbsp;</p>

<p class="has-text-align-none">HIV is a particularly tricky virus. When it infects a person, the virus infects and kills a specific <a href="https://clinicalinfo.hiv.gov/en/glossary/cd4-t-lymphocyte#:~:text=HIV%2FAIDS%20Glossary&amp;text=A%20type%20of%20lymphocyte.,system%20by%20destroying%20CD4%20cells.">type</a> of blood cell (called a T cell) that fights infections. This weakens the immune system and also prevents the immune system from killing HIV. If left untreated, an HIV infection develops into a severe disease called acquired immunodeficiency syndrome (<a href="https://www.hiv.gov/hiv-basics/overview/about-hiv-and-aids/what-are-hiv-and-aids">AIDS</a>). At that point, the virus has completely destroyed the immune system — this makes people more susceptible to a wide range of infections with little protection.</p>

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<p class="has-text-align-none">The newsletter is part of Vox’s <a href="https://www.vox.com/explain-it-to-me">Explain It to Me</a>, where we tackle a question from our audience and deliver a digestible explainer from one of our journalists. Have a question you want us to answer? Ask us <a href="http://www.vox.com/ask-vox">here</a>.</p>
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<p class="has-text-align-none">HIV spreads through contaminated bodily fluids, usually during sex or when people share needles.<strong> </strong>Scientists now believe that <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3234451/">HIV first spread to humans</a> from infected chimpanzees in Cameroon in Central Africa. The virus spread slowly and sporadically among humans, finding its way to modern-day Kinshasa, the Democratic Republic of Congo’s bustling capital city. From there, the virus went global, and in 1981, the Centers for Disease Control and Prevention first <a href="https://www.cdc.gov/museum/online/story-of-cdc/aids/index.html">documented</a> several cases of what would come to be known as HIV.&nbsp;&nbsp;</p>

<p class="has-text-align-none">Since those fateful days, almost <a href="https://www.who.int/data/gho/data/themes/hiv-aids#:~:text=Since%20the%20beginning%20of%20the,people%20have%20died%20of%20HIV.">90 million</a> people around the world have been infected with HIV, and more than 40 million have died from the disease. At one point, almost <a href="https://data.unaids.org/pub/report/2004/2004_epiupdate_en.pdf">5 million</a> people became infected with HIV each year, and some <a href="https://www.unaids.org/en/resources/fact-sheet#:~:text=AIDS%2Drelated%20deaths%20have%20been,1.7%20million%5D%20people%20in%202010.">2 million people died annually</a> from it.</p>

<p class="has-text-align-none">Today, the outcomes are much better. In 2023, <a href="https://www.who.int/data/gho/data/themes/hiv-aids#:~:text=Since%20the%20beginning%20of%20the,people%20have%20died%20of%20HIV.">some 600,000</a> people died from HIV, while just over 1 million people were newly infected with the disease. Scientists and public health officials have developed a slew of medications and interventions to prevent infection or keep the virus so in check that HIV-positive people have no symptoms and can live full, healthy lives. Ending AIDS actually seems feasible.&nbsp;</p>

<p class="has-text-align-none">But, despite such incredible progress, HIV remains strong in much of the world. These tools have not been enough and will not be enough to end the epidemic once and for all — alone. While more medical interventions, such as a true cure for HIV or a vaccine for the disease (which is likely still years, if not decades, away), would help, this is no longer really a problem of science. Ending the HIV epidemic has been plagued by trying to solve the seemingly insurmountable problem of equity and discrimination.</p>

<p class="has-text-align-none">In some places, especially <a href="https://files.aho.afro.who.int/afahobckpcontainer/production/files/iAHO_Mortality_Regional-Factsheet.pdf">African countries</a>, HIV — and complications from it — remains one of the leading causes of death. Certain populations — gay men, adolescent girls and young women, sex workers, people who use IV drugs, and people in prisons — are at a disproportionately high risk of not only becoming infected with HIV but also not receiving adequate treatment.</p>

<p class="has-text-align-none">“If this were just about developing products, doing the research and development, this epidemic would be over,” said <a href="https://avac.org/mitchell-warren/">Mitchell Warren</a>, the executive director of the international nonprofit <a href="https://avac.org/">AVAC</a>. “It&#8217;s not unique to HIV, but HIV is probably the most glaring example. HIV is an epidemic that is obviously about a virus, but it&#8217;s spread because of inequity, because of stigma, because of discrimination, because of criminalizing behaviors.”&nbsp;</p>

<p class="has-text-align-none">However, American and European support for the fight against HIV is waning. Governments are slashing critical funding and even considering <a href="https://www.politico.com/news/2025/01/16/risch-senate-republican-pepfar-program-jeopardy-00198702">eliminating</a> key HIV programs such as <a href="https://www.state.gov/pepfar/" data-type="link" data-id="https://www.state.gov/pepfar/">PEPFAR</a>, or the US President&#8217;s Emergency Plan for AIDS Relief. But relenting now risks a resurgence of the disease that could threaten not only human lives but economic and political stability as it did when the epidemic first emerged.</p>

<h2 class="wp-block-heading has-text-align-none"><strong>How far have – or haven’t – we come in ending HIV?</strong></h2>

<p class="has-text-align-none">Warren started his career in HIV in 1993. He was stationed in South Africa as the country was rapidly becoming the epicenter of the HIV epidemic. Patients with HIV wasted away in front of his eyes, he recalled. Roadsides were lined with coffin makers. Every weekend, Warren’s colleagues occupied their time traveling from one funeral to the next.&nbsp;</p>

<p class="has-text-align-none">At the time, HIV was a death sentence, and the only preventative tool physicians and public health officials had at their disposal was the male condom, which prevents the virus from spreading during intercourse but does nothing to protect drug users or homosexual couples who often don’t use condoms because they aren’t trying to prevent pregnancy. Condoms, of course, also do not prevent pregnant people from passing on the virus to their fetus, another way that HIV can be spread.</p>

<p class="has-text-align-none">In the first decade of the epidemic, drug companies created an antiretroviral therapy treatment that keeps the amount of virus in the body — known as the viral load — at such low levels that the virus couldn’t be spread from person to person. While these treatments did help reduce the massive number of HIV deaths, they weren’t enough to end the epidemic because these early treatments required patients to take dozens of pills a day. (And they were given after someone already had HIV, so they weren’t preventative.)&nbsp;</p>

<p class="has-text-align-none">Even setting aside the sheer cost and numerous side effects of taking that many drugs so frequently, getting patients to take all those pills was a major challenge even in wealthy countries. In places like South Africa and other developing countries with too few medical centers and doctors, distributing and stocking enough drugs and getting them into patient’s hands was insurmountable.&nbsp;</p>

<p class="has-text-align-none">It wasn’t until <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC4309625/#:~:text=In%202006%2C%20the%20approval%20of,%2C%20once%20a%20day'%20regimen">2006</a> that pharmaceutical companies developed the “one pill, once a day” regimen to treat HIV-positive patients, which helped ease logistical and adherence challenges. Then, in <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10384104/#:~:text=2">2012</a>, the Food and Drug Administration approved pre-exposure prophylaxis, or <a href="https://www.cdc.gov/hivnexus/hcp/prep/index.html">PrEP</a>, therapy, which allowed people without HIV to take medicines to&nbsp;prevent infection. Though PrEP is not a cheap option — it can cost up to <a href="https://www.goodrx.com/truvada/truvada-hiv-prep-cost-generic-how-to-save#:~:text=How%20much%20does%20PrEP%20cost%20without%20insurance?,200%20mg/25%20mg%20dose.&amp;text=For%20a%20year's%20worth%20of,there%20are%20ways%20to%20save.">$2,000</a> per patient per month in the US — HIV advocates hailed PrEP as a critical tool in the fight against HIV.&nbsp;</p>

<p class="has-text-align-none">Along the way, massive HIV programs like PEPFAR rolled out other campaigns and interventions — such as promoting safe sex practices, encouraging male circumcision, and rolling out rapid HIV testing services — to prevent the spread of HIV.&nbsp;</p>

<p class="has-text-align-none">But despite these amazing scientific achievements, HIV remains an enduring challenge not because of science but largely because of stigma, discrimination, and marginalization. While some <a href="https://www.who.int/data/gho/data/themes/hiv-aids/data-on-the-hiv-aids-response">20 million</a> people around the world today take HIV medication, about <a href="https://www.who.int/data/gho/data/themes/hiv-aids/data-on-the-hiv-aids-response">20 percent</a> of people with HIV cannot access treatment.&nbsp;</p>

<p class="has-text-align-none">Gay men, sex workers, and people who use IV drugs are all at higher risk of contracting HIV, but they are often hesitant to seek out testing or treatment because they fear doctors and nurses will treat them poorly, or worse, report them to authorities. Sex work is illegal in at least <a href="https://www.nswp.org/sex-work-laws-map">100</a> countries, and IV drug use is illegal in all but about <a href="https://www.citywide.ie/decriminalisation/countries.html">30 countries</a>. Even homosexuality remains criminalized in <a href="https://www.fairplanet.org/story/death-penalty-homosexualty-illegal/#:~:text=As%20of%202024%2C%20homosexuality%20is,violence%2C%20harassment%20and%20social%20stigma.">64 countries</a>, including about <a href="https://antigaylaws.org/regional/africa/">30 of 54</a> African countries, where the HIV burden is highest. The legal challenges have made it difficult for public health officials to implement certain interventions even when we know they work. Giving clean needles to IV drug users, for example, reduces the spread of HIV among drug users and yet is rarely, and even then controversially, implemented in very few countries.</p>

<p class="has-text-align-none">Then there is the challenge of gender equality. Adolescent girls and young women are also at a particularly high risk of contracting HIV, especially in certain parts of the world. In 2023, <a href="https://www.unaids.org/sites/default/files/media_asset/UNAIDS_FactSheet_en.pdf">62</a> percent of all new HIV infections in sub-Saharan Africa were among girls and young women. In <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC3499941/#:~:text=Women%2C%20especially%20in%20relationship%20dynamics,risk%20of%20HIV%20in%20women">some parts</a> of these countries, young girls, who lack the agency to insist on safe sex practices, are married to older men who have multiple sexual partners, which increases the risk of HIV transmission. Rape is unfortunately common in regions afflicted by conflict. In other situations, especially in refugee camps or places with limited economic opportunities, girls and women are forced to turn to sex work to survive.</p>

<p class="has-text-align-none">“We tend to see HIV finding the fault lines in society,” Warren explained. “This is a virus that is spread by sex and by drug use. Those are two behaviors that have been stigmatized and criminalized not just during 40 years of HIV, but for hundreds and thousands of years.”</p>

<h2 class="wp-block-heading has-text-align-none"><strong>How likely is it that we can make more progress against HIV/AIDS?</strong></h2>

<p class="has-text-align-none">Bridging cultural and logistical divides is what makes public health so challenging. I’ve worked in global health for almost 10 years, and I know that achieving public health goals, such as eliminating HIV, isn’t simply about inventing and rolling out medicines and interventions but about changing societal practices and cultural beliefs.&nbsp;</p>

<p class="has-text-align-none">But short of solving the persistent global challenges of inequality and discrimination, we can do more to ensure people around the world continue to have access to preventative care, testing services, and treatment. To do that, we need money — a lot of it.&nbsp;</p>

<p class="has-text-align-none">For the past decade, the US government has donated more than <a href="https://www.kff.org/hivaids/fact-sheet/u-s-federal-funding-for-hivaids-trends-over-time/">$5 billion</a> a year to the global fight against HIV; about half of those funds are routed through <a href="https://www.state.gov/pepfar/">PEPFAR</a>. Historically, PEPFAR has enjoyed bipartisan support, but in recent years, politicians — particularly from the right — have threatened to end or dramatically reduce global health funding to focus on bolstering domestic spending and improving the lives of Americans. Other politicians want to end PEPFAR because some funds are spent to improve and expand access to sexual and reproductive care. HIV is, after all, spread through sex. But the proximity of HIV care to abortion services is too close for many <a href="https://t.co/6cSSQJSfvg">Republican politicians</a>, meaning that, in this rising tide of anti-abortion views, the US government should also end funding for HIV.&nbsp;</p>

<p class="has-text-align-none">The fight against HIV is losing momentum around the world. Globally, funding for HIV dropped by about <a href="https://www.unaids.org/sites/default/files/media_asset/UNAIDS_FactSheet_en.pdf">8 percent</a> from $21.5 billion in 2020 to $19.8 billion in 2023, according to the Joint United Nations Programme on HIV/AIDS, or <a href="https://www.unaids.org/en">UNAIDS</a>. Between 2022 and 2023, the US and other major donor countries, including the European Commission, reduced their global funding for HIV and seem poised to <a href="https://www.politico.eu/article/fears-over-health-ngos-future-as-massive-eu-funding-cut-looms/">further</a> cut funding for global health more broadly. The future may be even more bleak: President Donald Trump announced on Tuesday that the US was <a href="https://www.reuters.com/world/us/trump-signs-executive-withdrawing-world-health-organization-2025-01-21/">cutting ties</a> with the <a href="https://www.who.int/">World Health Organization</a>, the UN’s health agency that plays a <a href="https://www.unaids.org/en/aboutunaids/unaidscosponsors/who">key role</a> in providing HIV treatment and care to millions of people, particularly those in low- and middle-income countries.</p>

<p class="has-text-align-none">The simple fact is that if global funds for HIV are reduced, we will see a rise in HIV cases and deaths. The global community has accomplished so much, but the fight is not over.</p>

<p class="has-text-align-none"><em>This story was featured in the Explain It to Me newsletter. Sign up&nbsp;</em><a href="https://www.vox.com/pages/explain-it-to-me-newsletter-sign-up"><em>here</em></a><em>.</em>&nbsp;<em>For more from Explain It to Me,&nbsp;</em><a href="https://link.chtbl.com/explainit?sid=site"><em>check out the podcast</em></a><em>.</em></p>

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			</author>
			
			<title type="html"><![CDATA[Giving healthy kids antibiotics saves lives. There’s a catch.]]></title>
			<link rel="alternate" type="text/html" href="https://www.vox.com/features/386178/antibiotics-drug-resistance-child-mortality" />
			<id>https://www.vox.com/?p=386178</id>
			<updated>2024-12-26T06:42:29-05:00</updated>
			<published>2024-12-26T06:42:00-05:00</published>
			<category scheme="https://www.vox.com" term="Features" /><category scheme="https://www.vox.com" term="Future Perfect" /><category scheme="https://www.vox.com" term="Health" /><category scheme="https://www.vox.com" term="Infectious Disease" /><category scheme="https://www.vox.com" term="Public Health" />
							<summary type="html"><![CDATA[This story was originally published in The Highlight, Vox&#8217;s member-exclusive magazine. To get early access to member-exclusive stories every month, join the Vox Membership program today. The sharp decline in child mortality rates is one of the great global success stories of the past several decades.&#160; In 1990, nearly 13 million children died before their [&#8230;]]]></summary>
			
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<img alt="An illustration of a young girl jumping rope. The jump rope is forming the shape of a pill and acting as a barrier to various bacteria" data-caption="" data-portal-copyright="Drew Shannon for Vox" data-has-syndication-rights="1" src="https://platform.vox.com/wp-content/uploads/sites/2/2024/12/DrewShannon_AntbioticTradeoff.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
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<p class="has-text-align-none"><em>This story was originally published in The Highlight, Vox&#8217;s member-exclusive magazine. To get early access to member-exclusive stories every month, </em><a href="https://www.vox.com/support-now?itm_campaign=article-header-Q42024&amp;itm_medium=site&amp;itm_source=in-article"><em>join the Vox Membership program today</em></a><em>.</em></p>

<p class="has-text-align-none">The <a href="https://www.vox.com/2019/5/9/18535778/child-mortality-global-poverty-literacy-good-news">sharp decline</a> in child mortality rates is one of the great global success stories of the past several decades.&nbsp;</p>

<p class="has-text-align-none">In 1990, nearly <a href="https://www.who.int/data/gho/data/themes/topics/topic-details/GHO/child-mortality-and-causes-of-death">13 million</a> children died before their fifth birthday, primarily from infectious diseases or complications during birth. By 2022, that number had fallen by more than <a href="https://data.unicef.org/topic/child-survival/under-five-mortality/">50 percent</a>, meaning that today, about 8 million fewer children are dying than were some 35 years ago.&nbsp;</p>

<p class="has-text-align-none">Overall <a href="https://www.vox.com/future-perfect/24100883/child-mortality-rate-worldwide-united-nations">development improvements</a>, alongside a handful of targeted public health interventions — ensuring that <a href="https://www.who.int/news-room/fact-sheets/detail/children-reducing-mortality">skilled health care workers are present during childbirth</a>, improving <a href="https://www.malteser-international.org/en/current-issues/our-response/health/child-mortality.html">access to clean water</a>, providing <a href="https://www.ncbi.nlm.nih.gov/books/NBK361904/">postnatal care</a>, and expanding <a href="https://www.vox.com/future-perfect/24138291/do-vaccines-work-explained-study-efficacy-evidence">vaccination</a>, to name a few — have helped ensure far more children live to see their fifth birthday and beyond.&nbsp;</p>

<p class="has-text-align-none">Yet despite that progress, around 5 million children younger than 5 years old still die prematurely each year, with about <a href="https://www.who.int/data/gho/data/themes/topics/topic-details/GHO/child-mortality-and-causes-of-death">80 percent</a> of those deaths occurring in sub-Saharan Africa and southern Asia. And progress to <a href="https://www.weforum.org/stories/2024/04/child-death-mortality-progress-sdg/">reduce child mortality has slowed</a> in recent years. Between 2015 and 2022, child mortality rates fell by only 2 percent, down from about 4 percent between 2000 and 2015.</p>

<p class="has-text-align-none">But one surprising intervention — periodically distributing antibiotics prophylactically to young children en masse — could help further reduce child mortality rates in some of the worst-affected countries. A <a href="https://www.nejm.org/doi/full/10.1056/NEJMoa2312093">study</a> published in August examined children in Niger, a country in West Africa with one of the <a href="https://www.cia.gov/the-world-factbook/field/infant-mortality-rate/country-comparison/">highest child mortality rates</a> in the world. Researchers found that twice-yearly mass distributions of an antibiotic to children between the ages of 1 and 5 reduced child mortality by 14 percent.&nbsp;</p>

<p class="has-text-align-none">If this sounds too good to be true — significant reductions in child deaths simply by giving them basic drugs designed to fight bacterial infections — it may be. This intervention around one major health challenge — childhood mortality — is somewhat controversial because it seems to directly run against another major health challenge: the rise of <a href="https://www.vox.com/future-perfect/353420/drug-resistant-bacteria-are-killing-more-and-more-humans-we-need-new-weapons">drug-resistant infections</a>. Such infections, which are caused by the overuse of antibiotics, claim an estimated <a href="https://www.vox.com/future-perfect/367247/antibiotic-resistance-bacteria-pasteur-act-big-pharma">1 million</a> lives every year, a number that could <a href="https://www.nature.com/articles/d41586-024-03033-w">nearly double by 2050</a>.&nbsp;</p>

<p class="has-text-align-none">“If you increase the amount of antibiotic exposure in the population, you are guaranteed to increase the risk of having drug resistance,” said <a href="https://pathology.wustl.edu/people/gautam-dantas-phd-2/">Gautam Dantas</a>, a professor at Washington University’s School of Medicine who studies the human microbiome and antimicrobial resistance. These drug-resistant pathogens can spread around the world, creating a public health threat for everyone.&nbsp;</p>

<p class="has-text-align-none">And there’s another question: While the positive results show promise, no one is exactly sure why giving antibiotics to children who have no overt sign of infection but still live in high-risk areas reduces overall child mortality in the community.</p>

<p class="has-text-align-none">Given the unknowns and potential to contribute to global drug resistance, the World Health Organization in 2020 strongly <a href="https://books.google.com/books?hl=en&amp;lr=&amp;id=Ko5FEAAAQBAJ&amp;oi=fnd&amp;pg=PR4&amp;dq=WHOWHO+guideline+on+mass+drug+administration+of+azithromycin+to+children+under+five+years+of+age+to+promote+child+survival2020World+Health+OrganizationGeneva&amp;ots=7mevxMNtCv&amp;sig=-7-5kFchG5gVM7XhYEIY4x9H2sE#v=onepage&amp;q=WHOWHO%20guideline%20on%20mass%20drug%20administration%20of%20azithromycin%20to%20children%20under%20five%20years%20of%20age%20to%20promote%20child%20survival2020World%20Health%20OrganizationGeneva&amp;f=false">recommended against mass antibiotic distribution</a> as a universal intervention. Instead, the agency suggested that public health officials pursue the intervention only in places where under 5 mortality is greater than 80 children per 1,000 births. In 2022, only <a href="https://data.unicef.org/topic/child-survival/under-five-mortality/#:~:text=The%20world%20made%20remarkable%20progress,a%20matter%20of%20urgent%20concern.">10 countries</a> recorded under 5 mortality rates higher than this threshold.&nbsp;</p>

<p class="has-text-align-none">The scientists who study and advocate for the mass distribution of antibiotics are well aware of these issues. The essential question: How does one weigh saving children’s lives against fueling another deadly health threat?&nbsp;</p>

<h2 class="wp-block-heading has-text-align-none">A safety net of antibiotics</h2>

<p class="has-text-align-none">The idea of mass distributing antibiotics to reduce child mortality has its origins in control programs for a specific disease: trachoma. <a href="https://www.who.int/news-room/fact-sheets/detail/trachoma#:~:text=Trachoma%20is%20a%20disease%20of,Blindness%20from%20trachoma%20is%20irreversible.">Trachoma</a> is a bacterial eye infection that can lead to visual impairment and irreversible blindness.&nbsp;</p>

<p class="has-text-align-none">Though the disease has plagued humanity for at least 10,000 years, by the early <a href="https://www.sightsavers.org/wp-content/uploads/2019/05/Sightsavers-History-of-trachoma-timeline.pdf">20th century</a> it had become a serious scourge, infecting anyone from soldiers to boarding school students. But the disease was <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC5093790/#:~:text=The%20introduction%20of%20antibiotics%20in,treatment%20of%20an%20active%20disease.">wiped out</a> in most developed countries in the 1950s and 1960s following the invention and widespread use of antibiotics, especially azithromycin.&nbsp;</p>

<p class="has-text-align-none">But trachoma has persisted in about 50 countries, mostly in poor, rural areas of Africa, Asia, the Middle East, as well as Central and South America. About <a href="https://www.who.int/news-room/fact-sheets/detail/trachoma">2 million</a> people today have blindness or visual impairment caused by trachoma and another 103 million are considered at risk of contracting the disease.&nbsp;&nbsp;</p>

<p class="has-text-align-none">In communities where trachoma is still a problem, the disease prevalence is high, <a href="https://idpjournal.biomedcentral.com/articles/10.1186/s40249-017-0345-8">ranging from 60 to 90 percent</a>. Because trachoma became so widespread, the World Health Organization in the early <a href="https://www.sightsavers.org/wp-content/uploads/2019/05/Sightsavers-History-of-trachoma-timeline.pdf">1990s</a> <a href="https://www.who.int/health-topics/trachoma#tab=tab_3">recommended</a> that health officials treat everyone in an affected community with the antibiotic azithromycin, whether or not they had been diagnosed with the disease. The thinking was that treating the entire community with an antibiotic would reduce the amount of bacteria circulating in the community, thus reducing transmission — much like mass vaccination is used to curtail viral outbreaks.&nbsp;</p>

<p class="has-text-align-none">In the early 2000s, researchers started <a href="https://pubmed.ncbi.nlm.nih.gov/21427395/">noticing that mass distribution of azithromycin</a> not only reduced trachoma, but also seemed to reduce overall child mortality. Scientists running a <a href="https://pubmed.ncbi.nlm.nih.gov/19724043/">trachoma control study in Ethiopia</a> hypothesized that because azithromycin was effective against other infectious diseases, including respiratory and diarrheal diseases and malaria — all leading causes of childhood death in the country — mass distribution of the drug might help save children’s lives.&nbsp;</p>

<p class="has-text-align-none">Other public health scientists probed this idea further by conducting mass antibiotic distribution trials in places where trachoma wasn’t found.&nbsp;</p>

<p class="has-text-align-none">In one 2018 <a href="https://www.nejm.org/doi/full/10.1056/NEJMoa1715474?logout=true">study known as the MORDOR trial</a> (MORDOR stands for Macrolides Oraux pour Réduire les Décès avec un Oeil sur la Résistance, French for “Oral Macrolides to Reduce Deaths with an Eye on Resistance”), researchers randomly selected more than 1,000 villages across Malawi, Niger, and Tanzania to either receive the mass distribution of azithromycin or a placebo intervention. Children who were between one month and five years in the intervention villages received a small dose of azithromycin twice a year for two years.&nbsp;</p>

<p class="has-text-align-none">At the end of the study, in communities where children had received the antibiotic, the overall annual mortality rate was lower — by about 3 percent in Tanzania, 6 percent in Malawi, and 18 percent in Niger — compared to the villages that received a placebo. The drop in mortality was even greater, about 25 percent, among the youngest children, those between 1 and 5 months old.</p>

<p class="has-text-align-none">While the results are promising, researchers still do not fully understand how mass azithromycin distribution reduces child mortality. One explanation is that the intervention works in a similar way as it does in trachoma-endemic settings, but instead of providing communities a blanket of protection against merely the Chlamydia trachomatis bacterium that <a href="https://www.ncbi.nlm.nih.gov/books/NBK559035/">causes trachoma</a>, it bestows protection against a wider range of bacteria, including the ones that cause the common respiratory diseases and diarrheal diseases that can kill young children in poor countries.&nbsp;</p>

<p class="has-text-align-none">“It may not be just that you get lucky and you treat a kid that happens to be sick that week,” said <a href="https://profiles.ucsf.edu/thomas.lietman">Thomas Lietman</a>, a professor at the Proctor Foundation at the University of California, San Francisco who has led studies on trachoma and was the senior author of the 2018 and 2024 child mortality studies.&nbsp;</p>

<p class="has-text-align-none">“We think it&#8217;s that we&#8217;re reducing the pathogen load in the community. And one of the reasons we think this is because there appears to be an indirect effect. In other words, you receive benefit just by your community being treated.”</p>

<h2 class="wp-block-heading has-text-align-none">The cost of saving lives</h2>

<p class="has-text-align-none">Even during these early trials, researchers were concerned about how giving antibiotics to kids might fuel another massive global challenge: <a href="https://www.who.int/news-room/fact-sheets/detail/antimicrobial-resistance#:~:text=AMR%20is%20a%20natural%20process,in%20humans%2C%20animals%20and%20plants.">antimicrobial resistance</a>, the process by which bacteria evolve the ability to evade antibiotics. It’s simply a matter of evolution: the more that antimicrobials are used, the more opportunities pathogens have to develop resistance to them. If that process continues long enough, it will eventually render these critical, life-saving medicines <a href="https://www.vox.com/future-perfect/2019/5/7/18535480/drug-resistance-antibiotics-un-report">ineffective</a>.&nbsp;</p>

<p class="has-text-align-none">At the same time, most major drug developers <a href="https://wellcome.org/news/its-time-fix-antibiotic-market">have turned away from making new antibiotics</a>. That means our stores of <a href="https://www.who.int/news/item/22-06-2022-22-06-2022-lack-of-innovation-set-to-undermine-antibiotic-performance-and-health-gains">effective antibiotics are dwindling</a>. If left unchecked, researchers predict that some <a href="https://www.nature.com/articles/d41586-024-03033-w">2 million</a> people might die from drug-resistant infections by 2050, making it a leading cause of death. But people won’t just die from drug-resistant infections. Life-saving surgeries and treatments such as chemotherapy, which massively damage the immune system, will become much riskier because it will be harder to prevent infections..</p>

<p class="has-text-align-none">In its antibiotic stewardship <a href="https://www.cdc.gov/antibiotic-use/data-research/facts-stats/index.html">guidelines</a>, the Centers for Disease Control and Prevention recommends that health care workers only prescribe antimicrobials if they know what pathogen is causing a patient’s illness. But the idea of mass distributing antibiotics to reduce childhood mortality runs entirely counter to that.&nbsp;</p>

<p class="has-text-align-none">“We&#8217;re taught in every health care field not to give antibiotics non-specifically; yet that&#8217;s exactly what we&#8217;re doing here,” Lietman said. “We&#8217;re giving antibiotics to children whether or not they&#8217;re sick, whether or not they have a particular pathogen.”</p>

<p class="has-text-align-none">However, it is unclear what impact mass distribution interventions have on drug resistance. After the MORDOR trial, researchers conducted follow-up studies where they collected swab samples from the children who received the antibiotic during the study and those who did not. Among children who participated in the <a href="https://www.ajtmh.org/content/journals/10.4269/ajtmh.19-0086">study in Tanzania</a>, researchers reported that there was no significant difference in the number of azithromycin-resistant strains of two types of bacteria between the two groups. Yet in Niger, <a href="https://www.nejm.org/doi/full/10.1056/NEJMc1901535">researchers found that children</a> who received the antibiotic harbored more drug-resistant strains.&nbsp;</p>

<p class="has-text-align-none">Other <a href="https://pubmed.ncbi.nlm.nih.gov/9114185/">studies</a>, though not <a href="https://pubmed.ncbi.nlm.nih.gov/12543738/">all</a>, that have assessed drug resistance in the wake of mass distribution campaigns for trachoma control have documented measurable but short-lived increases in drug-resistant bacterial strains.&nbsp;</p>

<p class="has-text-align-none">Regardless of whether and to what extent mass antibiotic distribution contributes to drug resistance, the intervention uses a small fraction of the total antibiotics consumed worldwide either by humans or livestock animals. In the 2018 MORDOR study, children received about 20 milligrams per kilogram of body weight which equates to about 360 milligrams for a 40-pound child or a total of, at most, 36 kilograms of antibiotics for the roughly 100,000 children that received the intervention across four distributions.&nbsp;</p>

<p class="has-text-align-none">Compare that to, say, the <a href="https://www.cidrap.umn.edu/antimicrobial-stewardship/new-fda-report-shows-more-antibiotics-being-sold-food-animals#:~:text=The%20latest%20summary%20report%20from,5.9%20million%20kg%20in%202021.">6.2 million kilograms</a> of medically important antibiotics sold for use in <a href="https://www.vox.com/future-perfect/2023/1/8/23542789/big-meat-antibiotics-resistance-fda">livestock operations</a> in the US in 2022. Perhaps it would be more effective to reduce antibiotic use in agriculture than target relatively miniscule antibiotic use during an intervention that saves children’s lives.</p>

<p class="has-text-align-none">But there may be other consequences to mass antibiotic use. A series of studies conducted mostly in the US and Europe have linked antibiotic use in childhood with an increased risk of developing <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC10134683/#:~:text=Antibiotic%20exposure%20in%20early%20infancy,according%20to%20these%20cohort%20studies.">obesity</a>, <a href="https://www.mayoclinicproceedings.org/article/S0025-6196(20)30785-0/fulltext">attention deficit hyperactivity disorder</a>, <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7957291/">asthma</a>, and other lifelong disorders.&nbsp;</p>

<p class="has-text-align-none">Still, it is important to note here that these studies are looking at a very different population than children in Niger who face a high risk of dying before they turn 5. Some research suggests the link between antibiotic use and obesity and other disorders may be <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC8093917/">related to alterations in the gut microbiome</a>, but it remains unclear exactly how antibiotics might cause poor health outcomes and what role other lifestyle factors might play. And those factors could be entirely different in a country like Niger or Tanzania than in the US.&nbsp;</p>

<p class="has-text-align-none">“Right now, the benefit outweighs the harm,” Dantas said. “Yes, you may encode some burden elsewhere, but you’ll save the life of a child.”</p>

<p class="has-text-align-none">It’s hard to argue that saving thousands — if not millions — of children&#8217;s lives doesn’t outweigh future threats of drug resistance or a possible heightened risk of developing chronic diseases. There are plenty of other ways to address the public health challenges posed by antibiotic resistance and chronic diseases that don’t put the lives of some of the poorest children in the world at risk.&nbsp;</p>

<p class="has-text-align-none">And there is one conclusion that is undeniable: If millions of young children were dying every year in the US, parents would demand that every possible intervention be used — whatever the future consequences.&nbsp;</p>
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			<author>
				<name>Jessica Craig</name>
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			<title type="html"><![CDATA[I saw the Hurricane Helene response up close. This is how disaster relief actually works.]]></title>
			<link rel="alternate" type="text/html" href="https://www.vox.com/future-perfect/384734/hurricane-helene-asheville-response-fema-volunteers-climate-change" />
			<id>https://www.vox.com/?p=384734</id>
			<updated>2024-11-15T16:00:07-05:00</updated>
			<published>2024-11-17T07:00:00-05:00</published>
			<category scheme="https://www.vox.com" term="Climate" /><category scheme="https://www.vox.com" term="Features" /><category scheme="https://www.vox.com" term="Future Perfect" /><category scheme="https://www.vox.com" term="Health" /><category scheme="https://www.vox.com" term="Natural Disasters" /><category scheme="https://www.vox.com" term="Public Health" />
							<summary type="html"><![CDATA[The storm damage in western North Carolina after Hurricane Helene swept through on September 27 was immense. More than 1,000 bridges, some 5,000 miles of state-owned roads, 160 water and sewage systems, and an estimated 126,000 homes were damaged or destroyed. At least 100 people were killed, and about 20 more were still missing as [&#8230;]]]></summary>
			
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<img alt="Two people use brooms and shovels to clear mud out of a kitchen flooded by a hurricane." data-caption="Cajun Army volunteers shovel mud inside a home that flooded in Swannanoa, North Carolina, in October 2024. | Jess Craig/Vox" data-portal-copyright="Jess Craig/Vox" data-has-syndication-rights="1" src="https://platform.vox.com/wp-content/uploads/sites/2/2024/11/volunteers-clearing-mud-in-a-home-copy_1123a5.png?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
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	Cajun Army volunteers shovel mud inside a home that flooded in Swannanoa, North Carolina, in October 2024. | Jess Craig/Vox	</figcaption>
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<p class="has-text-align-none">The storm damage in western North Carolina after Hurricane Helene swept through on September 27 was immense. More than 1,000 bridges, some <a href="https://www.cbsnews.com/news/hurricane-helenes-north-carolina-damage-53-billion-record/">5,000 miles</a> of state-owned roads, 160 water and sewage systems, and an estimated 126,000 homes were damaged or destroyed. At least <a href="https://abc11.com/post/hurricane-helene-aftermath-death-toll-tops-100-western-north-carolina-after/15489290/">100 people</a> were killed, and about <a href="https://www.nytimes.com/2024/10/22/us/helene-north-carolina-missing.html">20</a> more were still missing as of mid-October. North Carolina Gov. Roy Cooper estimated it would cost a record-breaking <a href="https://governor.nc.gov/news/press-releases/2024/10/23/governor-cooper-proposes-39-billion-state-funding-spur-hurricane-helene-relief-and-recovery">$53 billion</a> to repair damage and cover all recovery needs.&nbsp;</p>

<p class="has-text-align-none">It’s little surprise that in the weeks after the storm, grassroots response efforts inundated the region. Driving south from Bakersville into Asheville, nearly every church, grocery store, gas station, firehouse, and strip mall parking lot had been converted to some sort of supply distribution point or relief hub. Schools, agricultural centers, and abandoned gyms served as American Red Cross shelters housing nearly <a href="https://www.ncdps.gov/news/press-releases/2024/10/05/hurricane-helene-recovery-progresses-western-north-carolina#:~:text=Missing%20Persons,including%20assists%2C%20evacuations%20and%20rescues.">1,000 people</a> who lost their homes. Hand-painted signs pointing the way to a hot meal or free supplies dotted the roads. Droves of volunteers descended on downed trees with chainsaws, hacking a path through to isolated mountain communities and houses. With so many roadways damaged or simply washed away, nurses, paramedics, and other volunteers with medical training mounted ATVs to conduct welfare checks. Others loaded up mules and walked supplies into the mountains.&nbsp;</p>

<p class="has-text-align-none">Elsewhere, volunteers packed into neighborhoods to <a href="https://gocajunnavy.org/mucking-out-a-house-tips-for-safe-and-effective-cleanup/#:~:text=Flooding%20and%20hurricanes%20can,step%20in%20the%20recovery%20process.">muck out</a> homes — removing water-damaged items, gutting houses down to their studs, and disinfecting remaining surfaces to prevent mold and help the house dry out before it could be rebuilt. Nonprofit organizations such as <a href="https://www.operation-airdrop.com/">Operation Airdrop</a> and individuals with military experience flew around in privately owned helicopters conducting rescue operations and airdropping supplies to people cut off from toppled roadways. In the first two weeks after Hurricane Helene, there was a constant whir of helicopters flying overhead.&nbsp;</p>

<p class="has-text-align-none">“It’s been like a war zone,” a Swannanoa resident told Vox.</p>

<p class="has-text-align-none">But amid this deluge of goodwill and generosity pouring into western North Carolina, something sinister was also brewing: misinformation and outright false <a href="https://www.vox.com/today-explained-podcast/377464/hurricanes-milton-helene-misinformation-fema">accusations</a> about federal relief efforts, particularly about the Federal Emergency Management Agency (FEMA).</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2024/11/Volunteers-at-a-distribution-center-in-Swannanoa_resize.png?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="Three women stand among boxes of food and donated items piled under the awning of a rural gas station." title="Three women stand among boxes of food and donated items piled under the awning of a rural gas station." data-has-syndication-rights="1" data-caption="Volunteers organize clothing, food, and other donated supplies at a gas station in October in Swannanoa, North Carolina." data-portal-copyright="" />
<p class="has-text-align-none">One Facebook post claimed the Biden administration reallocated some $1 billion in funds from disaster relief to “<a href="https://x.com/Oilfield_Rando/status/1841112876678848650">house illegal immigrants</a>,” leaving FEMA underfunded to help hurricane relief and response efforts. Another rumor was that FEMA was limiting financial assistance for disaster survivors to $750 and that recipients would eventually have to repay those funds or risk losing their homes.&nbsp;</p>

<p class="has-text-align-none">Both claims were false, <a href="https://www.fema.gov/fact-sheet/myth-and-fact-north-carolina-helene-response">according to FEMA</a>. The initial payout was meant to allow survivors to cover any urgent needs such as prescription medicine they lost during the storm, said <a href="https://iem.com/who-we-are/leadership/elizabeth-a-zimmerman/">Elizabeth Zimmerman</a>, a former director of disaster operations at FEMA and now a senior executive advisor at <a href="https://iem.com/who-we-are/">IEM</a>, an emergency management company.</p>

<div class="wp-block-vox-media-highlight vox-media-highlight">
<h2 class="wp-block-heading" id="how-i-reported-this">How I reported this</h2>



<p class="has-text-align-none">I live on the eastern coast of North Carolina, so when I heard about the news of the devastation in the western part of the state, I knew that I wanted to cover the community response there. </p>



<p class="has-text-align-none">Criticism over FEMA’s slow response had been flying around on social media, and volunteers were reporting that locals were hesitant to come forward to receive aid. So I drove the six hours west to meet with residents, local politicians, first responders, and volunteers to hear about their experiences during and after the storm.</p>
</div>

<p class="has-text-align-none">“That money is not going to be taken back from anybody,” Zimmerman said. “It is not a loan. And that&#8217;s just the beginning.” Even just two weeks after the hurricane blew through, some homeowners told Vox they had already been promised additional assistance, in the realm of $40,000, to help rebuild their homes.&nbsp;</p>

<p class="has-text-align-none">This misinformation has occasionally hindered relief efforts.</p>

<p class="has-text-align-none">During the weekend of October 12, there was a rumor among residents and FEMA staff that “armed militias” were threatening FEMA staff, which led the agency to <a href="https://www.wyff4.com/article/fema-paused-north-carolina-helene-hurricane/62597640">briefly pause</a> some of its response activities. The Rutherford County Sheriff&#8217;s Office later <a href="https://www.nbcnews.com/tech/misinformation/armed-north-carolina-man-arrested-suspicion-making-threats-fema-worker-rcna175287">arrested and charged a man</a> who made public comments about harming FEMA employees. Late in October, local police in Tennessee also <a href="https://newschannel9.com/news/local/witnesses-saw-an-armed-group-harassing-helene-aid-workers-in-a-small-tennessee-town-sheri">reported</a> they were investigating reports of armed groups who were “harassing hurricane relief workers.”&nbsp;</p>

<p class="has-text-align-none">Beyond the outright false statements swirling on social media, much of the confusion and criticism comes down to a misunderstanding of how disaster response works, according to <a href="https://hagertyconsulting.com/employee/brock_long">Brock Long</a>, a former head of FEMA who now serves as the executive chair at <a href="https://hagertyconsulting.com/">Hagerty Consulting</a>, an emergency management consulting firm.&nbsp;</p>

<p class="has-text-align-none">Many erroneously believe that FEMA is ultimately responsible for all relief and recovery efforts. “People think it&#8217;s just FEMA comes in and they take over,” Zimmerman said. “They do not take over. They cannot take over.”</p>

<p class="has-text-align-none">Even in a disaster the scale of Hurricane Helene, FEMA plays only a small role in the much larger recovery and relief effort. “It’s a team sport,” Long said, and there are four major players: local county and state governments, the federal government, the private sector, and most importantly, the bedrock of disaster response — volunteers.&nbsp;</p>

<p class="has-text-align-none">Misinformation in the wake of a natural disaster is nothing new, but prolonged power and cell service outages have made it worse. The erosion of local media and reliance on unverified information on social media has also exacerbated the misinformation crisis; if unchecked, it will continue to complicate future disaster response efforts. Understanding how disaster response really works and empowering volunteers and communities to be more prepared for these catastrophes will help us be more resilient in the face of threats.</p>

<h2 class="wp-block-heading has-text-align-none" id="how-disaster-response-works"><strong>How disaster</strong> response works</h2>

<p class="has-text-align-none">Local county and state governments are ultimately responsible for managing disaster recovery and relief efforts. However, in many cases — and particularly in remote places like rural western North Carolina — there are limited financial and human resources for disaster response, and counties can quickly become overwhelmed.&nbsp;</p>

<p class="has-text-align-none">An affected county government can reach out to neighboring counties for additional resources, be it manpower or equipment. If that influx of additional support is not sufficient, county governments can then ask the state government for assistance.&nbsp;</p>

<p class="has-text-align-none">If the resources available at the state level are still not enough to meet the needs of disaster-affected communities, the governor can then request assistance from FEMA. The FEMA administrator then gets in touch with the National Security Council at the White House to request that the president declare an emergency or major disaster declaration.&nbsp;</p>

<p class="has-text-align-none">This process can all happen within days or even hours. In the case of Hurricane Helene, the Biden administration approved an emergency <a href="https://www.fema.gov/press-release/20240926/president-joseph-r-biden-jr-approves-emergency-declaration-north-carolina">declaration</a> for North Carolina on September 26, the same day Hurricane Helene made landfall in Florida.&nbsp;</p>

<p class="has-text-align-none">Once an emergency declaration has been approved, it unlocks a huge influx of federal funds. FEMA has doled out more than $200 million to individuals and households for recovery, according to a FEMA spokesperson. The US Department of Transportation has also allocated <a href="https://highways.dot.gov/newsroom/biden-harris-administration-sends-north-carolina-100-million-emergency-relief-funding">$100 million</a> to rebuild bridges and roads in the state. Cooper has also proposed to provide an additional <a href="https://governor.nc.gov/news/press-releases/2024/10/23/governor-cooper-proposes-39-billion-state-funding-spur-hurricane-helene-relief-and-recovery">$3.9 billion</a> in state funds for recovery efforts.&nbsp;</p>

<p class="has-text-align-none">In addition to federal funds, an emergency authorization also allows FEMA to tap into an entire family of federal agencies, including the National Guard, Army Corps of Engineers, and the Departments of Energy, Education, and Transportation, among others.&nbsp;</p>

<p class="has-text-align-none">All federal agencies involved in disaster response, alongside representatives from major volunteer organizations such as the <a href="https://www.redcross.org/about-us/our-work/disaster-relief/hurricane-relief/hurricane-helene.html">American Red Cross</a>, convene in the National Response Coordination Center at FEMA’s headquarters in Washington, with additional coordination at regional headquarters and disaster-affected states. At each location, staff and volunteers work to identify community needs, recruit personnel, procure critical equipment and material items, and coordinate the overall response.</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2024/11/mdnatg-delivering-supplies_edit.png?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="A military helicopter unloading bags of supplies in a green field. People carry bags to a pickup truck." title="A military helicopter unloading bags of supplies in a green field. People carry bags to a pickup truck." data-has-syndication-rights="1" data-caption="The Maryland National Guard delivers supplies to Spruce Pine, North Carolina." data-portal-copyright="" />
<p class="has-text-align-none">What this all means is that FEMA plays more of a high-level management and coordinator role that supports the state. It is not, as it is often believed to be and blamed when it fails to be, the final authority on disaster response. “The way that disaster [response] works is that they&#8217;re typically locally executed, state managed, and federally supported,” Long said.&nbsp;</p>

<p class="has-text-align-none">But local, state, and federal governments are still just one of four major groups that help communities recover from disasters. Another key player is the private sector: the power, water, and communications companies, private health care facilities, and other businesses that own and operate local infrastructure that might need to be repaired and reopened following a disaster.&nbsp;</p>

<p class="has-text-align-none">About <a href="https://www.npr.org/2024/10/14/nx-s1-5150158/thousands-are-still-without-power-more-than-2-weeks-after-hurricane-helene#:~:text=MYERS:%20Well%2C%20a%20week%20after,was%20running%20on%20a%20generator.">1 million</a> people in North Carolina lost power immediately after Hurricane Helene. At the time of writing, nearly <a href="https://outages.ncelectriccooperatives.com/outages/maps">2,000</a> people in the state were still without power and more than <a href="https://www.nytimes.com/interactive/2024/10/25/climate/private-wells-hurricane-flood.html">150,000</a> people were either without water or remain under boil-water mandates. In some of the hardest to reach areas, volunteer and relief workers told me power may not be restored until January. While FEMA often takes the heat when these services aren’t rapidly restored, the agency does not actually have any jurisdiction over this work, Long said.&nbsp;</p>

<p class="has-text-align-none">For all the importance of local, state, and federal government agencies and private sector companies in disaster response, volunteers, churches, and community-based groups are even more vital. </p>

<p class="has-text-align-none">“The most important tool in the toolbox when it comes to response and recovery are the volunteer organizations active in disaster,” Long said.&nbsp;</p>

<h2 class="wp-block-heading has-text-align-none" id="the-people-who-make-up-disaster-response"><strong>The people who make up disaster response</strong></h2>

<p class="has-text-align-none">In the two weeks following Hurricane Helene, there was such an influx of food, water, and other supplies to western North Carolina that churches and volunteer groups on the ground were running out of storage space and were turning away donations. It demonstrated how, despite all the focus on the federal government, volunteers are the bedrock of disaster relief. They can quickly amass huge amounts of supplies and deploy resources to any area of the country long before state and federal governments have completed their bureaucratic processes to mobilize a response.&nbsp;</p>

<p class="has-text-align-none">“A lot of times, state and local and federal governments have to adhere to big, bulky laws, policies, and concepts, but the volunteer organizations active in disaster do not, Long said. “And so a lot of times the most effective use of the volunteer organizations is pointing them in the right direction of the citizens’ needs that cannot be fulfilled by the federal government.</p>

<p class="has-text-align-none">Most major volunteer groups that help with disaster recovery and response are part of a formal coalition, the Voluntary Organizations Active in Disaster (VOAD). There is a national VOAD as well as associations for <a href="https://www.nvoad.org/state-territory-voad/">each US state</a> and territory. While disaster relief and recovery efforts will always be a bit of organized chaos with well-meaning individuals and groups pouring in from around the country, these coalitions help to coordinate volunteer activities; ensure that funds, equipment, and people are evenly distributed across a disaster area; and reduce the duplication of efforts.&nbsp;&nbsp;</p>

<p class="has-text-align-none">Perhaps more importantly, many volunteers and organizations that are leading relief efforts are from affected areas, which is crucial for the kind of long-term recovery and rebuilding needed after a catastrophe of this magnitude. Immediately after a major disaster like Helene, there is a huge influx of donations and volunteers, but after a few months, the disaster fades from news headlines. Donations dwindle, while volunteers from the opposite side of the country stop coming or divert to another disaster. But local volunteers stay for the months or even years that it takes to rebuild their communities.&nbsp;&nbsp;</p>

<p class="has-text-align-none">In the parking lot of First Baptist Church in Swannanoa, on the eastern outskirts of Asheville, Dana Williams, 44, a neonatal ICU nurse from nearby Henderson County, has been volunteering at a makeshift medical clinic providing care to locals. She arrived four days after the hurricane hit, after being trapped in her home by downed trees.&nbsp;</p>

<p class="has-text-align-none">“I&#8217;m a nurse at heart. I&#8217;m a fixer. I want to help always. And so the first couple of days after the storm, we were stuck at the house. I felt so useless,” Williams said. “For years, whenever there would be a major disaster somewhere, I would wish I could go and help those people. Never in a million years did I think it would happen in my own backyard.”</p>

<p class="has-text-align-none">When Williams arrived at the makeshift clinic, other nurses had set out a folding table; with little more than a box full of blood pressure cuffs and ibuprofen, they started providing any kind of care they could.&nbsp;</p>

<p class="has-text-align-none">“Initially, it was just very grassroots,” Williams said. “I mean, we started here and we were like, ‘We&#8217;re just going to see what people need and what we can do.‘ We&#8217;re hands; we&#8217;re bodies. We have medical training.”</p>

<p class="has-text-align-none">At first, the nurses mostly provided first aid and trauma care, treating wounds and respiratory infections and rashes from the dirt and mud that pervaded the entire town after the storm. The volunteers worked to replace prescription medications that had been lost during the storm and to make sure that people who depended on oxygen had fresh tanks. The nurses also provided some basic medical education, making sure that everyone in the area, long accustomed to being able to drink from their local creek, knew that the water was now contaminated because of the flooding.&nbsp;</p>

<p class="has-text-align-none">Over time, the group of volunteers also started focusing on treating people with chronic diseases, while working toward ensuring that people had access to specialty health care services disrupted by the storm, such as chemotherapy. The nurses also connected with the American Red Cross and other larger organizations and started procuring and distributing medical supplies across the region. Donations poured in, and Williams has been able to procure even the most niche medical devices.&nbsp;</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2024/11/volunteer-nurse-inside-a-storage-unit-stocked-with-medical-supplies-in-swananoa-nc_oct2024_resize-1.png?quality=90&#038;strip=all&#038;crop=0,0,100,100" alt="A woman in jeans and a baseball cap stands between rows of shelves in her garage piled to the ceiling with supplies." title="A woman in jeans and a baseball cap stands between rows of shelves in her garage piled to the ceiling with supplies." data-has-syndication-rights="1" data-caption="Neonatal ICU nurse Dana Williams has been volunteering at a makeshift medical clinic — at a church on the eastern outskirts of Asheville — providing care to local residents. " data-portal-copyright="" />
<p class="has-text-align-none">Williams is committed to volunteering until all needs are met. She is storing extra medical supplies in her home garage. Recently, she started working toward building a similar volunteer clinic in Bat Cave, a rural area hard hit by the hurricane that has been almost completely cut off from aid. And while Williams is committed, she recognizes that churches and businesses that have loaned out their buildings and parking lots for relief efforts will at some point want to return to business as usual.&nbsp;</p>

<p class="has-text-align-none">“They have to get back to being the businesses that they are to survive now,” Williams said. “But I think if it becomes necessary, as time goes on, I think people are gonna be like, ‘Okay, we need to do this for this community’ … Mountain people are a different breed, and when the call goes out in two months, they will all show up again, just like this. So I don&#8217;t have any concerns that anybody&#8217;s going to be left behind. I think that everybody who has been involved to this point, we know that this is not a days or weeks endeavor.”</p>

<p class="has-text-align-none">Even before the storm, there was a lack of medical care and a shortage of health care workers across western North Carolina. <a href="https://mahec.net/rhi/wnc-health-disparities">All 16 counties</a> that make up the region had a shortage of primary care health workers, eight had no practicing psychiatrist, and seven had no OB-GYNs, according to the <a href="https://mahec.net/about-us/who-we-are">Mountain Area Health Education Center</a>, a nonprofit regional medical provider. Lenore Ellis, program director at the Center for Rural Health Innovation, told me almost everyone in need of specialized services had to travel to Asheville or into Tennessee. Many schools relied on telehealth services to help kids see a provider.&nbsp;</p>

<p class="has-text-align-none">Williams hopes that hurricane relief efforts will eventually lead to long-term improvements in local health care. “I didn&#8217;t realize what the community needs really were because it&#8217;s just a whole different perspective when you spend your career inside the walls of the hospital,” she said. Swannanoa and other small towns nestled in the Appalachian Mountains need more primary care and general practitioners but also affordable access to specialists such as oncologists.&nbsp;</p>

<p class="has-text-align-none">“Free care would be wonderful because a lot of these people are going to need free care for a long time, and that wasn&#8217;t really accessible here before,” she said.</p>

<h2 class="wp-block-heading has-text-align-none" id="learning-how-to-respond-better-to-the-next-disaster"><strong>Learning how to respond better to the next disaster</strong></h2>

<p class="has-text-align-none">Ariel Morris, 26, had only lived in Beacon Village, a Swannanoa neighborhood, for about three months before the hurricane blew in. Morris recalled that in the early morning hours of September 27, as Helene descended on the area, there was at first just a lot of rain and wind, like any other bad storm coming through.&nbsp;</p>

<p class="has-text-align-none">“But then, we got a little bit too much, and then the Montreat Dam and the Bee Tree Dam both let out at the exact same time — at the height of the storm,” Morris recalled.&nbsp;</p>

<p class="has-text-align-none">There are about 20 homes in the Beacon Village neighborhood. Half of them, including the house where Morris was staying with her mom, sat on a slight elevation. When the dams overflowed, the other half of the neighborhood flooded within minutes. Around 7 am that day, Morris and some of her neighbors heard people screaming for help. When they looked down toward the yelling, they saw their neighbors standing on their roofs or clutching their chimneys as their cars and sheds rushed by them.&nbsp;</p>

<p class="has-text-align-none">Morris’s neighbor, John Arndt, a recreational kayaker from Oregon, grabbed some rope and jumped in one of the kayaks stored outside his house and paddled out to people and pulled them toward an island of higher ground where Morris and other neighbors had gathered. Morris told her mom to keep calling 911 until someone answered but she couldn’t get through or the operator hung up on her. Finally, someone answered only to say, “We&#8217;re flooded with calls. Please stop calling.”</p>

<p class="has-text-align-none">Another neighbor pulled off his insulin pump, jumped barefoot into one of Arndt’s other kayaks without even a lifejacket, and also started rescuing people, sometimes hacking through roofs to free people trapped in their attic. In all, Arndt and his neighbor rescued 15 people, 10 pets, and a bearded dragon, Morris said. One elderly neighbor couldn’t hang on to the kayak long enough to be pulled out of the floodwaters so Arndt and his neighbor wrapped her in a tarp and blankets and waited for help to arrive, but it wasn’t until around 6 pm that firefighters from Wilmington, on the eastern coast of North Carolina, arrived and took over the rescue operations.</p>

<p class="has-text-align-none">As a kayaker, Arndt had some training to rescue people from whitewater rivers, not necessarily from massive flooding. “I’ve been involved in rescues kayaking, but you don’t have cars and tires floating past you and power lines and alarms going off and a bunch of different people yelling,” Arndt said.&nbsp;</p>
<img src="https://platform.vox.com/wp-content/uploads/sites/2/2024/11/Local-stand-outside-the-home-they-rented-in-Beacon-Village-in-Swananoa-NC_Oct2024_resize.png?quality=90&#038;strip=all&#038;crop=0,5.0260416666667,100,89.947916666667" alt="A man and a woman stand on their front porch looking out on their personal belongings scattered in their front yard." title="A man and a woman stand on their front porch looking out on their personal belongings scattered in their front yard." data-has-syndication-rights="1" data-caption="Local residents who were renting a home that was flooded during Hurricane Helene survey the damage in their front yard in October 2024." data-portal-copyright="" />
<p class="has-text-align-none">Locals and communities are the last major players in disaster response, according to Long, but not all communities are well-equipped to respond when disaster strikes. National surveys have revealed that about <a href="https://newsroom.clevelandclinic.org/2018/02/01/new-cleveland-clinic-survey-only-half-of-americans-say-they-know-cpr">50 percent</a> of Americans know how to do CPR, but only around <a href="https://www.health.harvard.edu/heart-health/why-dont-more-people-know-cpr#:~:text=Although%2065%25%20of%20people%20in,to%20date%20on%20their%20training.">20 percent</a> are up to date with the training. A FEMA survey reported that only <a href="https://community.fema.gov/PreparednessConnect/s/article/Results-from-the-2023-National-Household-Survey-on-Disaster-Preparedness#:~:text=The%202023%20survey%20conducted%20from,disaster%20within%20the%20last%20year.">51 percent</a> of Americans feel prepared for a disaster.&nbsp;</p>

<p class="has-text-align-none">“Why do we allow people to graduate from some of the most prestigious universities in the state of North Carolina and still not know how to do CPR or invest $1 toward retirement or become financially resilient?” Long asked.&nbsp;</p>

<p class="has-text-align-none">“We&#8217;ve got to get citizens to realize that in any situation, you are the true first responder, until the official first responder arrives, and there&#8217;s always a time gap. Are you trained for the first five to six minutes of any emergency situation in your household or out in public?” he added.</p>

<p class="has-text-align-none">There is also a <a href="https://www.cbsnews.com/news/emt-shortage-quit-ambulance/">nationwide shortage of emergency medical technicians</a>, an ongoing problem that needs to be addressed. But poorly prepared civilians and a lack of first responders are only two challenges. All the key players involved in disaster response need to reform and improve.&nbsp;</p>

<p class="has-text-align-none">“I think down the road, we really need to have a conversation around what are the core capabilities that should exist at the local, state, and federal levels,” Long said. “How do we better utilize the resources of nonprofits? How do we increase tangible skills within our citizenry? It starts with neighbor helping neighbor all the way to the Federal Emergency Management Agency.”</p>

<p class="has-text-align-none">According to Long, one way to strengthen community-level disaster response is for Congress to start incentivizing local jurisdictions and states for prioritizing preparedness, for instance by passing and enforcing strong building codes, having disaster-cognizant land-use plans, and not building infrastructure on vulnerable land. The North Carolina government has not fully implemented updated building codes — which require better flood and wind protection in homes — and that has caused the state to lose out on some <a href="https://ncnewsline.com/2024/10/16/building-codes-led-north-carolina-to-lose-out-on-70m-in-disaster-prep-funds-state-says/#:~:text=Legislature-,Building%20codes%20led%20North%20Carolina%20to%20lose%20out%20on%20%2470,disaster%20prep%20funds%2C%20state%20says">$70 million</a> in disaster preparedness funds from FEMA.</p>

<p class="has-text-align-none">Some nonprofit disaster response organizations offer various types of training for civilians, but there is no formal state or federal programming or earmarked funding for these efforts.</p>

<p class="has-text-align-none">Until individuals, communities, local and state governments, federal agencies, and private companies come together to strengthen disaster preparedness, then response efforts will be lacking, and that will cost lives. Storms are not the only disasters we face. “We have to be able to build dynamic capability at all levels to be able to handle different disasters, from cyberattacks to hurricanes,” Long said.&nbsp;</p>
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			<entry>
			
			<author>
				<name>Jessica Craig</name>
			</author>
			
			<title type="html"><![CDATA[Zika is still spreading. Why don’t we have a vaccine yet?]]></title>
			<link rel="alternate" type="text/html" href="https://www.vox.com/future-perfect/379740/zika-virus-vaccine-mosquitoes-climate-change" />
			<id>https://www.vox.com/?p=379740</id>
			<updated>2024-10-24T17:23:59-04:00</updated>
			<published>2024-10-25T08:30:00-04:00</published>
			<category scheme="https://www.vox.com" term="Future Perfect" /><category scheme="https://www.vox.com" term="Health" /><category scheme="https://www.vox.com" term="Health Care" /><category scheme="https://www.vox.com" term="Infectious Disease" /><category scheme="https://www.vox.com" term="Policy" /><category scheme="https://www.vox.com" term="Politics" /><category scheme="https://www.vox.com" term="Public Health" /><category scheme="https://www.vox.com" term="Vaccines" /><category scheme="https://www.vox.com" term="World Politics" />
							<summary type="html"><![CDATA[When it comes to infectious diseases, the mosquitos are winning. In the last year, health officials reported a spike in dengue and have recorded infections even in nontropical areas, where the disease typically did not spread. Malaria is resurging in parts of North and South America, Africa, and Asia. Even Anthony Fauci, the former director [&#8230;]]]></summary>
			
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<img alt="A woman standing in a narrow street holds two babies wearing frilly white dresses and pink ribbons." data-caption="Maria Jose holds her twin granddaughters Heloisa and Heloa Barbosa, both born with microcephaly, outside of their house in Areia, Paraiba state, Brazil on April 16, 2017. The twins were born to Raquel who said she contracted Zika virus during her pregnancy. | &lt;span style=&quot;font-family: -apple-system, BlinkMacSystemFont, &quot;Segoe UI&quot;, Roboto, Oxygen-Sans, Ubuntu, Cantarell, &quot;Helvetica Neue&quot;, sans-serif;&quot;&gt;Mario Tama/Getty Images&lt;/span&gt;" data-portal-copyright="&lt;span style=&quot;font-family: -apple-system, BlinkMacSystemFont, &quot;Segoe UI&quot;, Roboto, Oxygen-Sans, Ubuntu, Cantarell, &quot;Helvetica Neue&quot;, sans-serif;&quot;&gt;Mario Tama/Getty Images&lt;/span&gt;" data-has-syndication-rights="1" src="https://platform.vox.com/wp-content/uploads/sites/2/2024/10/gettyimages-669361122.jpg?quality=90&#038;strip=all&#038;crop=0,0,100,100" />
	<figcaption>
	Maria Jose holds her twin granddaughters Heloisa and Heloa Barbosa, both born with microcephaly, outside of their house in Areia, Paraiba state, Brazil on April 16, 2017. The twins were born to Raquel who said she contracted Zika virus during her pregnancy. | <span>Mario Tama/Getty Images</span>	</figcaption>
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<p class="has-text-align-none">When it comes to infectious diseases, the mosquitos are winning. In the last year, health officials reported a <a href="https://www.who.int/news-room/fact-sheets/detail/dengue-and-severe-dengue">spike</a> in <a href="https://www.vox.com/future-perfect/24099834/dengue-fever-virus-mosquito-brazil-vaccine">dengue</a> and have recorded infections even in nontropical areas, where the disease typically did not spread. Malaria is resurging in parts of North and South <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6471461/">America</a>, <a href="https://www.carbonbrief.org/malaria-resurgence-feared-in-ethiopia-amid-el-nino-and-climate-change/">Africa</a>, and <a href="https://www.aplma.org/blog/fighting-resurgence-of-malaria-among-migrant-populations-along-the-thai-myanmar-border---expert-interview-with-prof-nosten-smru">Asia</a>. Even <a href="https://www.niaid.nih.gov/about/anthony-s-fauci-md">Anthony Fauci</a>, the former director of the National Institute of Allergy and Infectious Diseases, contracted a nasty case of West Nile from a <a href="https://www.nytimes.com/2024/10/07/opinion/fauci-west-nile-virus.html">mosquito in his backyard</a> in DC.</p>

<p class="has-text-align-none">Some of the increase can be <a href="https://www.vox.com/future-perfect/2019/3/7/18254825/zika-dengue-yellow-fever-mosquitos-climate-change">explained</a> by mosquitos thriving in new places thanks to changes in temperature and rainfall. Mosquitoes and the pathogens they carry are also developing <a href="https://www.vox.com/health/23814358/west-nile-virus-symptoms-mosquito-repellant-disease-bite-insecticide-resistance">resistance</a> to the pesticides and drugs previously used to eliminate them.&nbsp;</p>

<div class="wp-block-vox-media-highlight vox-media-highlight">
<h2 class="wp-block-heading">This story was first featured in the <a href="https://www.vox.com/pages/future-perfect-newsletter-signup">Future Perfect newsletter</a>.</h2>



<p class="has-text-align-none">Sign up <a href="https://www.vox.com/pages/future-perfect-newsletter-signup">here</a> to explore the big, complicated problems the world faces and the most efficient ways to solve them. Sent twice a week.</p>
</div>

<p class="has-text-align-none">The US government and other global health donors have invested billions to develop new vaccines and medicines for mosquito-borne diseases such as <a href="https://www.cdc.gov/dengue/hcp/vaccine/index.html#:~:text=around%20their%20homes.-,About%20Dengvaxia,made%20with%20natural%20rubber%20latex.">dengue</a>, <a href="https://www.who.int/news/item/06-10-2021-who-recommends-groundbreaking-malaria-vaccine-for-children-at-risk#:~:text=Strong%20safety%20profile:%20To%20date,moderate%20to%20high%20malaria%20transmission.">malaria</a>, and <a href="https://www.cdc.gov/chikungunya/prevention/chikungunya-vaccine.html#:~:text=One%20chikungunya%20vaccine%20(called%20IXCHIQ,heart%20disease%2C%20high%20blood%20pressure)">chikungunya</a>. One virus, though, that has faded into the background still has no vaccine and no cure: Zika.</p>

<p class="has-text-align-none">In <a href="https://www.who.int/news-room/feature-stories/detail/the-history-of-zika-virus">2015</a>, the Zika virus — which had previously rarely infected humans — suddenly spread rapidly, leading to more than a <a href="https://www.lshtm.ac.uk/newsevents/news/2022/brazilian-babies-born-zika-virus-syndrome-greater-risk-death-first-three-years#:~:text=In%20April%202015%20until%20November,learning%20disabilities%20in%20later%20life.">million</a> cases over two years. Even worse, scientists observed a horrifying phenomenon: A small fraction of infected pregnant women gave birth to children with what became known as congenital Zika syndrome, characterized by severe <a href="https://www.cdc.gov/zika/czs/index.html#:~:text=Overview%20of%20Zika%2Dassociated%20birth,making%20it%20difficult%20to%20move">birth defects</a> such as hearing and vision loss, feeding problems, and <a href="https://www.hopkinsmedicine.org/health/conditions-and-diseases/zika#:~:text=Overview,infected%20with%20Zika%20while%20pregnant.">microcephaly</a>, a neurological condition in which babies have abnormally small heads. In Brazil, which was hardest hit by the epidemic, more than <a href="https://www.lshtm.ac.uk/newsevents/news/2022/brazilian-babies-born-zika-virus-syndrome-greater-risk-death-first-three-years#:~:text=In%20April%202015%20until%20November,learning%20disabilities%20in%20later%20life.">3,500</a> babies were born with Zika-related birth defects.</p>

<p class="has-text-align-none">Fortunately, the number of Zika infections worldwide declined rapidly toward the end of 2016, albeit for reasons still largely unknown. A leading theory is that the virus spread so fast that communities developed <a href="https://www.thelancet.com/journals/lanpub/article/PIIS2468-2667(18)30029-X/fulltext">herd immunity</a>. Or perhaps mosquito control efforts, like spraying pesticides and encouraging communities to eliminate sources of standing water, wiped out the virus’s transmission route. The continental US has <a href="https://www.cdc.gov/zika/zika-cases-us/index.html">not recorded</a> any cases since 2018 and US territories have not since 2019. </p>

<p class="has-text-align-none">Unfortunately, as Zika cases declined, so did global funding and interest in Zika. Public health officials and, more importantly, donors and policymakers turned toward other priorities, including the coming Covid-19 pandemic. No Zika vaccine ever came to fruition. </p>

<p class="has-text-align-none">Despite the decline in attention, Zika is still spreading in many countries. In the first half of 2023, health officials recorded about <a href="https://www.gov.uk/government/publications/emerging-infections-monthly-summaries/infectious-disease-surveillance-and-monitoring-for-animal-and-human-health-summary-january-to-june-2023#:~:text=Between%201%20January%20and%2030,virus%20cases%20were%20locally%20acquired.">27,000</a> Zika infections in the Americas, with Brazil the most affected country with more than <a href="https://www.gov.uk/government/publications/emerging-infections-monthly-summaries/infectious-disease-surveillance-and-monitoring-for-animal-and-human-health-summary-january-to-june-2023#:~:text=Between%201%20January%20and%2030,virus%20cases%20were%20locally%20acquired.">2,700</a> cases. Thousands of babies are still being born with preventable disabilities.  </p>

<p class="has-text-align-none">“With a safe and effective Zika vaccine, we could eliminate the possibility of congenital Zika syndrome, and I think that would have a huge impact,” said <a href="https://publichealth.jhu.edu/faculty/798/anna-p-durbin">Anna Durbin</a>, a professor of international health and global disease epidemiology and control at Johns Hopkins University. “Even if there are few cases of congenital Zika syndrome, just the emotional, financial effect of that is huge.”</p>

<p class="has-text-align-none">Scientists and global health experts <a href="https://www.gavi.org/vaccineswork/zika-hasnt-disappeared-heres-why-it-should-stay-our-radar">warn</a> that Zika, alongside other mosquito-borne infectious diseases, could make a broader resurgence. The first step to defeating pandemics is, of course, prevention, and a Zika vaccine is vital to that goal.</p>

<p class="has-text-align-none">But major hurdles stand in the way. Private pharmaceutical companies aren’t willing to invest in vaccine development because so few people are getting infected now — and those who are getting infected largely live in relatively poor countries. Researchers say governments aren’t investing sufficient public funds in vaccine development. And it is almost impossible to run a traditional clinical trial for the few vaccines hastily developed during the 2015 outbreak. </p>

<h2 class="wp-block-heading has-text-align-none"><strong>A brief history of Zika&nbsp;</strong></h2>

<p class="has-text-align-none">In the early months of<a href="https://www.who.int/news-room/feature-stories/detail/the-history-of-zika-virus"> 2015</a>, doctors in Brazil noticed a sudden surge of patients with an odd skin rash. They alerted the World Health Organization (WHO) that an unknown infectious disease might be emerging. Within a<a href="https://www.cdc.gov/mmwr/volumes/66/wr/mm6612a4.htm"> few months</a>, scientists identified the cause of the outbreak: <a href="https://www.who.int/health-topics/zika-virus-disease#tab=tab_1">Zika</a>, a virus first discovered in the Zika forest of Uganda in <a href="https://www.who.int/news-room/feature-stories/detail/the-history-of-zika-virus">1947</a> that is spread by certain types of mosquitoes.</p>

<p class="has-text-align-none">At first, there was little cause for concern. Since the <a href="https://www.who.int/news-room/fact-sheets/detail/zika-virus#:~:text=Overview,detected%20across%20Africa%20and%20Asia.">1960s</a>, the virus has caused only sporadic infections in Africa and Asia, and then later in the Americas. Moreover, Zika doesn’t cause symptoms in about <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312578/">80 percent</a> of people who are infected, while others typically experience only minor illness characterized by a low-grade fever, skin rash, and conjunctivitis. By March 2015, of the <a href="https://www.who.int/news-room/feature-stories/detail/the-history-of-zika-virus">7,000</a> or so people who had developed the skin rash in Brazil, no one had died.</p>

<p class="has-text-align-none">But then in <a href="https://www.paho.org/en/stories/zika-unknown-epidemic-and-pahos-swift-response">September</a>, Brazilian doctors began noticing a troubling new pattern. Somewhere between <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5578104/">2 percent</a> and <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312578/">6</a> percent of babies born to women who had Zika had small, misshaped brains, a condition called <a href="https://www.hopkinsmedicine.org/health/conditions-and-diseases/zika#:~:text=Overview,infected%20with%20Zika%20while%20pregnant.">microcephaly</a>. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7312578/">Other</a> babies were missing key brain structures or had other malformations. Clinicians called it congenital Zika syndrome.</p>

<p class="has-text-align-none">To make matters worse, the virus was spreading rapidly beyond the borders of Brazil. In December, the Pan American Health Organization <a href="https://www.paho.org/en/stories/zika-unknown-epidemic-and-pahos-swift-response">declared</a> the Zika outbreak an international health emergency. The WHO followed suit in <a href="https://www.who.int/news-room/fact-sheets/detail/zika-virus">February</a> the next year. By the end of <a href="https://www.paho.org/en/stories/zika-unknown-epidemic-and-pahos-swift-response">2016</a>, 48 countries and territories across North and South America were reporting cases. </p>

<p class="has-text-align-none">Funding for the outbreak response <a href="https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(16)30332-2/fulltext">surged</a>. The US government alone put up <a href="https://www.kff.org/global-health-policy/issue-brief/the-status-of-funding-for-zika-the-presidents-request-congressional-proposals-final-funding/">$1.1 billion</a> to support activities such as surveillance, education, mosquito control, and vaccine research. Various research <a href="https://pmc.ncbi.nlm.nih.gov/articles/PMC9694033/">groups</a>, mostly in the US, the UK, and South Korea, developed some 40 vaccine candidates. A handful of those vaccines underwent small phase 1 and 2 clinical trials and seemed promising, <a href="https://virologyphd.hms.harvard.edu/people/dan-hung-barouch">Dan Barouch</a>, a professor of immunology at Harvard Medical School, recalled.</p>

<p class="has-text-align-none">Then suddenly the outbreak subsided. Countries went from reporting <a href="https://www.cdc.gov/mmwr/volumes/66/wr/mm6612a4.htm#:~:text=In%20the%20non%2DLatin%20Caribbean,at%20high%20levels%20through%20July.">thousands of cases</a> every few months in 2016 to only a few, sporadic cases in 2017.</p>

<p class="has-text-align-none">This was, obviously, a good thing. Unfortunately, though, once a disease poses a minimal threat to high-income countries, where most research and development takes place, progress toward developing effective vaccines and medicines tends to stall. Governments, scientists, and pharmaceutical companies transition funding and attention to the next health emergency, leaving low-income countries in the global South to fend for themselves.</p>

<p class="has-text-align-none">But the rapid rise and fall of the Zika outbreak posed another challenge. Two years into the outbreak, when candidate vaccines were ready for real-world testing, there were no longer enough susceptible people for a phase 3 clinical trial.</p>

<h2 class="wp-block-heading has-text-align-none"><strong>Why Zika vaccine development has stalled</strong></h2>

<p class="has-text-align-none">Before a regulatory body such as the US Food and Drug Administration can <a href="https://www.cdc.gov/vaccines/basics/how-developed-approved.html#:~:text=even%20after%20approval.-,Approving%20the%20vaccine,details%20about%20the%20manufacturing%20process">approve</a> a new vaccine, it generally must be proven safe and effective in a large <a href="https://med.uc.edu/depart/psychiatry/research/clinical-research/crm/trial-phases-1-2-3-defined#:~:text=to%20Phase%20III.-,Phase%20III,studies%20are%20randomized%20and%20blinded.">phase 3 clinical trial</a>. A few thousand people are vaccinated and then observed to measure the dose’s effectiveness once some of those people contract the disease. So researchers need a large pool of people willing to be in a trial and who may also be exposed to the disease.</p>

<p class="has-text-align-none">During the first year or so of the 2016-2017 Zika outbreak, there would have been more than enough people for such a trial. But researchers first had to complete smaller phase 1 and 2 trials, which primarily focus on safety. By the time some vaccines were ready for phase 3 trials, the outbreak was too small to provide sufficient subjects. </p>

<p class="has-text-align-none">Even today, whenever Zika sporadically pops up around the world, there are typically only a few hundred cases at a given time, and researchers can’t pinpoint where and when cases will arise. They still can’t start up a trial, Durbin explained.</p>

<p class="has-text-align-none">There are alternative pathways to getting a vaccine approved that don’t require phase 3 clinical trials. According to Durbin, drug developers don’t want to cover those costs because they are unlikely to recoup them, given how few people are getting Zika now. </p>

<p class="has-text-align-none">A lack of government funding for vaccine research and development is compounding this problem. Government funding for various diseases comes in waves with the outbreaks, first for Ebola then for Zika, and then for Covid-19.</p>

<p class="has-text-align-none">On the bright side, if another large-scale Zika outbreak were to occur, scientists already have a handful of vaccine candidates that are ready for larger clinical trials. Scientists and vaccine manufacturers would still need to make enough vaccines for a large trial and receive approval from authorities and ethics review boards in whichever countries the trials take place.</p>

<p class="has-text-align-none">Even though transmission is much lower than in 2015 and 2016, Durbin says there is still an urgent need for a vaccine.</p>

<p class="has-text-align-none">“Women who were living in Brazil during that outbreak were terrified if they were pregnant, absolutely terrified of what would happen to their babies,” she said. “It would provide tremendous peace of mind.”&nbsp;&nbsp;</p>

<p class="has-text-align-none">The peace of mind of mothers in the global South, however, isn’t enough to move large drug companies.</p>
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